| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 |
|---|---|---|---|---|---|---|---|---|
OPERATING ACTIVITIES | ||||||||
Net Income (Loss) Attributable to Parent | ||||||||
-153,723 | -57,060 | -84,413 | -384,164 | -62,718 | -38,837 | -14,063 | 29,611 | -10,083 |
Items not involving cash: | ||||||||
Deferred income tax benefit | ||||||||
-12,661 | -4,282 | -24,320 | -105,061 | -16,185 | 0 | 0 | - | - |
Depreciation | ||||||||
2,028 | 2,181 | 2,027 | 1,092 | 589 | 529 | 613 | 866 | 986 |
Gain on sale of property and equipment | ||||||||
-20 | 26 | 3 | -174 | 0 | 80 | 0 | - | - |
Stock-based compensation expense | ||||||||
6,799 | 6,241 | 15,117 | - | - | - | - | - | 633 |
Unrealized foreign exchange losses (gains) | ||||||||
68 | -1,003 | 2,374 | 1,003 | 21,966 | 4,218 | 18 | - | 20 |
Warrant issuance costs | ||||||||
- | - | - | - | - | - | - | 47 | 80 |
Change in fair value of warrant liability | ||||||||
- | - | -22 | 530 | 3,341 | -10,383 | -3,530 | -3,822 | 579 |
Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration, Liability | ||||||||
-200 | -7,298 | 1,359 | 1,568 | 770 | 0 | 0 | - | - |
Impairment of Intangible Assets (Excluding Goodwill) | ||||||||
43,836 | 14,811 | 40,798 | 253,197 | 39,007 | 0 | 0 | - | - |
Impairment of goodwill | ||||||||
22,471 | 0 | - | 138,150 | 0 | 0 | - | - | - |
Site consolidation non-cash portion | ||||||||
0 | 396 | 0 | - | - | - | - | - | - |
Net equity investment gain or loss | ||||||||
-22,522 | 19,557 | - | - | - | - | - | - | - |
Gain on investment | ||||||||
- | - | 0 | - | - | - | - | - | - |
Net equity investment gain (loss) | ||||||||
- | - | 0 | - | - | - | - | - | - |
Non Cash Royalty Revenue Related To Sale Of Future Royalties | ||||||||
1,656 | 0 | - | - | - | - | - | - | - |
Non-cash interest expense | ||||||||
2,099 | 0 | - | - | - | - | - | - | - |
Net accretion and amortization of investments in marketable securities | ||||||||
275 | 0 | - | - | - | - | - | - | - |
Net change in operating items: | ||||||||
Fair value of warrants issued in conjunction with debt facility | ||||||||
- | - | - | - | - | - | - | - | 35 |
Accounts receivable | ||||||||
-227 | 1,029 | 129 | -735 | -628 | 1,887 | -889 | 190 | -2,397 |
Accrued revenue | ||||||||
0 | -128 | 0 | - | - | - | - | - | - |
Accrued revenue | ||||||||
- | - | - | 0 | -349 | 360 | -2,008 | 2,188 | -621 |
Deferred expenses | ||||||||
- | - | - | - | - | -167 | -231 | -361 | 226 |
Investment tax credits receivable | ||||||||
0 | 49 | 47 | 47 | 188 | 52 | 31 | -323 | -71 |
Inventory | ||||||||
- | - | - | - | - | - | - | - | -148 |
Prepaid expenses and other assets | ||||||||
-1,606 | 648 | 833 | 115 | -159 | 773 | 776 | -97 | 107 |
Accounts payable and accrued liabilities | ||||||||
-2,410 | -1,266 | 736 | 26 | -2,489 | 6,253 | 130 | -197 | -2,142 |
Deferred revenue | ||||||||
0 | -2,742 | 2,727 | - | - | - | - | - | - |
Deferred rent and inducements | ||||||||
- | - | -693 | 0 | 0 | - | - | - | - |
Deferred revenue | ||||||||
- | - | - | -1,066 | -13,090 | 13,171 | -153 | -655 | 354 |
Site consolidation accrual | ||||||||
-983 | 1,331 | 0 | - | - | - | - | - | - |
Other liabilities | ||||||||
-665 | 0 | - | - | - | - | - | - | - |
Net cash used in operating activities | ||||||||
-71,006 | -67,866 | -48,640 | -57,885 | -56,382 | -12,421 | -6,737 | 32,908 | -7,830 |
INVESTING ACTIVITIES | ||||||||
Purchase of investments | ||||||||
- | - | -35,086 | 82,551 | -9,645 | 41,982 | 0 | - | - |
Acquisition of restricted investment | ||||||||
- | - | - | 12,601 | 0 | 0 | - | - | - |
Cash acquired through acquisition | ||||||||
- | - | - | 0 | 324 | 0 | 0 | - | - |
Acquisition of investments | ||||||||
58,759 | 121,580 | - | - | - | - | - | - | - |
Disposition of investments | ||||||||
87,675 | 118,566 | - | - | - | - | - | - | - |
Proceeds from sale of property and equipment | ||||||||
11 | 25 | 3 | 25 | 0 | 80 | 0 | 3 | - |
Acquisition of property and equipment | ||||||||
589 | 1,138 | 7,264 | 3,996 | 2,287 | 1,056 | 725 | 15 | 60 |
Net cash provided by / (used in) investing activities | ||||||||
28,338 | -4,127 | 27,825 | -99,123 | 7,682 | -42,958 | -725 | -12 | -60 |
FINANCING ACTIVITIES | ||||||||
Proceeds from loan payable | ||||||||
- | - | - | 12,001 | 0 | 0 | - | - | - |
Issuance of common shares pursuant to the Open Market Sale agreement | ||||||||
18,601 | 0 | - | 0 | 142,177 | 56,477 | 32,038 | 3,844 | 4,598 |
Proceeds from the sale of future royalties | ||||||||
18,549 | 0 | - | - | - | - | - | - | - |
Promissory note repayment | ||||||||
0 | 12,001 | 0 | - | - | - | - | - | - |
Proceeds from sale of Preferred Shares, net of issuance costs | ||||||||
0 | 66,265 | 48,869 | 0 | 0 | - | - | - | - |
Issuance of common shares pursuant to exercise of options | ||||||||
307 | 1,382 | 100 | 192 | 1,651 | 2,616 | 389 | 71 | 10 |
Issuance of common shares pursuant to exercise of warrants | ||||||||
- | - | 353 | 445 | 42 | 1,583 | 289 | 632 | - |
Net cash provided by financing activities | ||||||||
37,457 | 55,646 | 49,322 | 12,638 | 143,870 | 60,676 | 32,716 | 4,547 | 4,609 |
Effect of foreign exchange rate changes on cash and cash equivalents | ||||||||
68 | -1,003 | 2,372 | 1,004 | -578 | -1,827 | -3,561 | 550 | -100 |
Decrease in cash and cash equivalents | ||||||||
-5,143 | -17,350 | 30,879 | -143,366 | 94,592 | 3,470 | 21,693 | 37,993 | -3,381 |
Supplemental cash flow information | ||||||||
Fair value of warrants exercised on a cashless basis | ||||||||
- | - | - | - | - | -116 | 1,404 | 211 | - |
Non-cash transactions: | ||||||||
Acquired property and equipment in trade payables | ||||||||
- | - | - | 1,057 | 0 | 0 | - | - | - |
Preferred shares dividends accrued | ||||||||
11,149 | 10,091 | 0 | - | - | - | - | - | - |
Initial investment in Genevant | ||||||||
0 | 27,377 | 0 | - | - | - | - | - | - |
Interest Paid, Excluding Capitalized Interest, Operating Activities | ||||||||
0 | 104 | - | - | - | - | - | - | - |
Increase (Decrease) In Fair Value Of Contingent Consideration Liability | ||||||||
-173 | -7,298 | - | - | - | - | - | - | - |
Fair value of warrants exercised on a cashless basis | ||||||||
- | - | - | - | - | - | 1,404 | 211 | - |
Investment tax credits received | ||||||||
- | - | 108 | 0 | 24 | 0 | 10 | 323 | 103 |
Acquisition of Arbutus Inc. net of cash acquired | ||||||||
- | - | - | 0 | 381,618 | 0 | 0 | - | - |
Fair value of warrants issued in conjunction with public offering | ||||||||
- | - | - | - | - | - | - | 851 | 751 |
Fair value of warrants issued in conjunction with debt facility | ||||||||
- | - | - | - | - | - | - | - | 35 |