| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||||||||||
Net loss | ||||||||||||||||
-137,920 | -137,165 | -143,974 | -99,430 | -101,848 | -95,514 | -86,604 | -92,724 | -69,434 | -70,138 | -58,289 | -75,905 | -77,785 | -71,579 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | ||||||||||||||||
Depreciation | ||||||||||||||||
7,055 | 7,172 | 7,346 | 7,331 | 7,276 | 7,188 | 6,862 | 6,508 | 5,786 | 5,032 | 4,254 | 3,637 | 3,405 | 3,126 | 0 | 0 | 0 |
Amortization | ||||||||||||||||
851 | 838 | 669 | 651 | 646 | 622 | 588 | 536 | 474 | 391 | 305 | 237 | 182 | 160 | 0 | 0 | 0 |
Share-based compensation expense | ||||||||||||||||
9,022 | 11,053 | 12,244 | 14,466 | 15,009 | 16,202 | 15,301 | 14,458 | 12,790 | 10,804 | 9,952 | 9,037 | 9,433 | 8,821 | 0 | 0 | 0 |
Realized loss on available-for-sale debt securities | ||||||||||||||||
- | - | - | - | - | 2,473 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Unrealized foreign exchange gains | ||||||||||||||||
-4,426 | -1,076 | -5,348 | -7,880 | -12,514 | -9,747 | -3,208 | 2,478 | 16,409 | 8,599 | 6,257 | 2,516 | -242 | 1,314 | 0 | 0 | 0 |
Other | ||||||||||||||||
-1 | -185 | -220 | 68 | 74 | 237 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Changes in operating assets and liabilities: | ||||||||||||||||
Increase in receivables and other operating assets | ||||||||||||||||
-2,030 | 1,436 | 21,097 | 10,411 | 1,642 | 5,162 | 15,666 | 21,249 | 15,712 | 7,346 | 1,441 | 4,833 | 7,857 | 6,533 | 0 | 0 | 0 |
Increase in non-current operating assets | ||||||||||||||||
1,690 | 1,450 | -1,720 | -1,918 | -846 | -742 | -3,089 | -2,756 | -2,009 | -2,115 | 304 | 374 | -369 | -2,221 | 0 | 0 | 0 |
Decrease in payables | ||||||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Increase in deferred revenue | ||||||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Increase (decrease) in payables and deferred revenue | ||||||||||||||||
- | - | - | - | - | -40,923 | -23,953 | -1,598 | 5,067 | 12,439 | 20,463 | 10,957 | 13,961 | 16,808 | 0 | 0 | 0 |
Net cash provided by (used in) operating activities | ||||||||||||||||
-59,440 | -112,500 | -131,664 | -92,117 | -93,312 | -104,388 | -94,059 | -90,509 | -73,155 | -54,315 | -30,589 | -59,444 | -57,928 | -48,168 | 0 | 0 | 0 |
Acquisition of property, plant and equipment | ||||||||||||||||
880 | 1,592 | 1,512 | 1,973 | 2,910 | 3,910 | 5,675 | 6,594 | 14,298 | 24,643 | 29,457 | 29,784 | 22,047 | 11,506 | 0 | 0 | 0 |
Acquisition of intangibles | ||||||||||||||||
1,429 | 1,482 | 1,168 | 1,710 | 993 | 798 | 747 | 113 | 137 | 369 | 543 | 684 | 660 | 1,279 | 0 | 0 | 0 |
Maturity of short-term deposits | ||||||||||||||||
- | - | - | - | - | - | - | - | - | 40,625 | 64,525 | 54,573 | 73,238 | 73,377 | 0 | 0 | 0 |
Investment in short-term deposits | ||||||||||||||||
- | - | - | - | - | - | - | - | - | 18,000 | 18,000 | 18,000 | 44,849 | 42,837 | 0 | 0 | 0 |
Maturity or redemption of marketable securities | ||||||||||||||||
128,998 | 125,303 | 115,853 | 121,645 | 132,664 | 138,038 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Investment in marketable securities | ||||||||||||||||
121,347 | 27,284 | 94,322 | 133,214 | 142,201 | 150,787 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net cash (used in) provided by investing activities | ||||||||||||||||
5,342 | 94,945 | 18,851 | -15,252 | -13,440 | -17,457 | -5,057 | 3,752 | -89,805 | -126,081 | -69,111 | -73,119 | 5,682 | 17,755 | 0 | 0 | 0 |
Cash flows from financing activities | ||||||||||||||||
Proceeds from issuance of common stock, net of issuance costs of $979 and $nil | ||||||||||||||||
0 | - | - | - | - | - | - | - | - | 103,167 | 0 | 0 | 0 | - | - | - | - |
Proceeds from exercise of stock options | ||||||||||||||||
1,224 | 366 | 470 | 979 | 1,539 | 3,037 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net cash provided by financing activities | ||||||||||||||||
91,774 | 366 | 470 | 100,632 | 101,192 | 102,690 | 102,586 | 2,794 | 43,705 | 103,568 | 0 | 0 | 0 | - | - | - | - |
Effect of currency exchange rate changes on cash, cash equivalents and restricted cash | ||||||||||||||||
-1,299 | -372 | -1,174 | -793 | 2,215 | 3,335 | 4,216 | 4,316 | 2,382 | 2,328 | 0 | 0 | 0 | - | - | - | 0 |
Net increase (decrease) in cash and cash equivalents | ||||||||||||||||
36,370 | -17,568 | -113,517 | -7,530 | -3,345 | -15,820 | 7,686 | -79,647 | -116,873 | -74,500 | 4,610 | -28,969 | 6,429 | -35,975 | 0 | 0 | 0 |