| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 |
|---|---|---|---|---|---|---|---|---|
CASH FLOWS FROM OPERATING ACTIVITIES: | ||||||||
NET LOSS | ||||||||
-48,279 | -65,743 | -43,758 | -19,515 | -17,969 | -16,813 | -15,527 | -7,301 | -5,903 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation and amortization | ||||||||
3,258 | 3,446 | 2,692 | 469 | 469 | 247 | 210 | 182 | 219 |
Noncash Interest Expense Related to Notes Payable | ||||||||
- | - | - | - | - | - | - | - | 847 |
Loss on Sale of Inventory | ||||||||
- | - | - | - | - | - | - | - | 1,934 |
Loss on disposal of fixed assets | ||||||||
-207 | -122 | -10 | 0 | - | - | - | - | -0 |
Stock-based compensation | ||||||||
2,650 | 2,223 | 1,561 | 1,250 | 1,711 | 1,248 | 888 | 626 | 22 |
Asset impairment charge | ||||||||
- | - | 845 | 0 | - | - | - | - | - |
Warrant liability | ||||||||
- | - | - | - | -67 | 74 | -43 | 0 | - |
Amortization of debt discount | ||||||||
1,180 | 1,104 | 781 | 676 | 353 | 133 | 91 | 2 | 740 |
Loss on extinguishment of debt | ||||||||
- | - | - | - | -719 | 0 | - | - | - |
Loss on extinguishment of debt | ||||||||
-9,962 | 0 | -1,021 | 0 | - | - | - | - | - |
Gain on transfer of plasma center assets | ||||||||
11,527 | 0 | - | - | - | - | - | - | - |
Amortization of deferred financing costs | ||||||||
- | - | - | - | 39 | 125 | 99 | 2 | 0 |
Payment-in-kind interest | ||||||||
- | - | - | - | 124 | 176 | 0 | - | - |
Non-cash interest expense related to notes payable | ||||||||
- | - | - | - | - | - | - | 1 | - |
Loss on sale of equipment | ||||||||
- | - | - | - | - | - | - | -18 | - |
Amortization of license revenue | ||||||||
-142 | -142 | -142 | -142 | -127 | -75 | -44 | 0 | - |
Changes in operating assets and liabilities: | ||||||||
Accounts receivable | ||||||||
2,077 | -2,487 | 2,862 | 93 | 540 | 383 | -39 | -39 | 0 |
Inventories | ||||||||
34,650 | 5,987 | -589 | 1,574 | 1,737 | 39 | 403 | 118 | -308 |
Prepaid expenses and other current assets | ||||||||
773 | 540 | 941 | 202 | -32 | -155 | 190 | 48 | -5 |
Deposits and other assets | ||||||||
-107 | 208 | 482 | 0 | - | 14 | -593 | -115 | - |
Restricted Cash | ||||||||
- | - | - | - | - | - | - | - | -90 |
Accounts payable | ||||||||
3,274 | -20 | 2,812 | 476 | 202 | -937 | 1,608 | -244 | 40 |
Accrued expenses | ||||||||
806 | 406 | 614 | 416 | -199 | 1,351 | 76 | 150 | 284 |
Accrued interest | ||||||||
- | - | - | - | - | -69 | -36 | 0 | - |
Deferred Revenue | ||||||||
- | - | - | - | 1,525 | 0 | 1,700 | 0 | - |
Other current and non-current liabilities | ||||||||
-190 | 174 | -11 | - | - | - | - | - | - |
Other current and non-current liabilities | ||||||||
- | - | - | -30 | - | - | - | - | - |
Deferred rent liability | ||||||||
- | - | - | - | 45 | -22 | -22 | -22 | -22 |
Net cash used in operating activities | ||||||||
-76,193 | -62,678 | -37,271 | -18,268 | -15,418 | -14,704 | -10,887 | -6,903 | -1,431 |
CASH FLOWS FROM INVESTING ACTIVITIES: | ||||||||
Sales of short-term investments | ||||||||
- | - | 5,390 | 16,657 | 16,414 | - | - | - | - |
Purchase of short-term investments | ||||||||
- | - | - | 15,680 | 18,130 | 1,717 | 2,935 | 0 | - |
Purchase of property and equipment | ||||||||
3,811 | 2,095 | 2,676 | 73 | 26 | 2,323 | 196 | 118 | 0 |
Cash acquired in acquisition transaction | ||||||||
- | - | 12,500 | 0 | - | - | - | - | - |
Net cash provided by (used in) investing activities | ||||||||
-3,811 | -2,095 | 15,213 | 904 | -1,741 | -4,040 | -3,131 | -118 | -0 |
CASH FLOWS FROM FINANCING ACTIVITIES: | ||||||||
Proceeds from Hercules note payable, net of fees | ||||||||
- | - | - | - | - | 9,850 | 1,000 | 3,906 | 0 |
Repurchase of common stock | ||||||||
- | - | - | - | - | - | - | 150 | 0 |
Proceeds from Convertible Notes Payable | ||||||||
- | - | - | - | - | - | - | - | 1,500 |
Principal payments on note payable | ||||||||
30,000 | 0 | 20,000 | 0 | 15,300 | 0 | - | 200 | 200 |
Payment of end of term fee | ||||||||
2,760 | 0 | 1,790 | 0 | - | - | - | - | - |
Payment of debt refinancing fees | ||||||||
6,499 | 0 | - | - | - | - | - | - | - |
Proceeds from issuance of related party note payable | ||||||||
- | - | 15,000 | 0 | - | - | - | - | - |
Proceeds from issuance of note payable | ||||||||
72,500 | 0 | 30,000 | 4,000 | - | - | - | - | - |
Prepayment penalty of early extinguishment of note payable | ||||||||
- | - | - | - | 229 | 0 | - | - | - |
Payment of debt issuance costs | ||||||||
1,679 | 0 | 1,650 | 47 | 228 | 30 | - | 25 | - |
Proceeds from Oxford note payable | ||||||||
- | - | - | - | 16,000 | 0 | - | - | - |
Proceeds from issuance of common stock, net of offering expenses | ||||||||
48,397 | 42,944 | 39,199 | 12,900 | 10,257 | 0 | 27,030 | 17,287 | 0 |
Proceeds from the exercise of stock options | ||||||||
75 | 13 | 7 | 0 | 49 | 0 | - | - | - |
Payment of Hercules end of term fee | ||||||||
- | - | - | - | 132 | 0 | - | - | - |
Debt issuance costs | ||||||||
- | - | - | - | - | - | 0 | - | 0 |
Equity issuance costs | ||||||||
- | - | - | - | 0 | 12 | 386 | 1,338 | 0 |
Payments on finance lease obligations | ||||||||
29 | 16 | 0 | 15 | 13 | 12 | 11 | 9 | 9 |
Payments of leasehold improvement loan | ||||||||
0 | 19 | 16 | - | - | - | - | - | - |
Net cash provided by financing activities | ||||||||
80,002 | 42,921 | 60,750 | 16,838 | 10,401 | 9,795 | 27,632 | 19,470 | 1,290 |
Net (decrease) increase in cash and cash equivalents | ||||||||
-2 | -21,852 | 38,692 | -526 | -6,758 | -8,950 | 13,613 | 12,447 | -141 |
Cash paid for interest | ||||||||
- | - | - | - | 1,326 | 785 | 382 | 1 | 15 |
Conversion of notes payable and accrued interest into common stock | ||||||||
- | - | - | - | - | - | - | 262 | - |
Reclassification of equity issuance costs to additional paid-in capital | ||||||||
- | - | - | - | 12 | 0 | 428 | 0 | - |
Accrued equity issuance costs | ||||||||
- | - | - | - | - | 55 | 41 | 69 | - |
Warrants issued in connection with note payable | ||||||||
- | - | - | - | 367 | 402 | 0 | 229 | 0 |
Conversion of notes payable and interest in private placement | ||||||||
- | - | - | - | - | - | - | - | 0 |
End of term liability in connection with note payable | ||||||||
- | - | - | - | 1,432 | 0 | 26 | 106 | 0 |
Elimination of warrant liability | ||||||||
- | - | - | - | 408 | - | 186 | 0 | - |
Stock retained by stockholders of shell company | ||||||||
- | - | - | - | - | - | - | 0 | - |
Preferred stock issued upon note payable and interest conversion | ||||||||
- | - | - | - | - | - | - | - | 9,636 |
Equity issuance costs, accrued and not paid | ||||||||
- | - | - | - | - | - | - | - | 421 |
Issuance of common stock through the cashless exercise of warrants | ||||||||
- | - | - | - | - | - | - | - | 0 |
Stock issued to shell company | ||||||||
- | - | - | - | - | - | - | - | 0 |