| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||||||||||||||
Grant | ||||||||||||||||||||
- | - | - | - | - | 3,888 | 5,171 | 6,650 | 0 | - | 0 | 0 | - | - | - | - | - | - | - | - | - |
Grant | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 4,751 | - | 4,966 | 4,890 | 6,944 | 6,085 | 0 | 0 | 0 |
Operating expenses: | ||||||||||||||||||||
Research and development | ||||||||||||||||||||
64,773 | 64,600 | 58,832 | 49,922 | 44,238 | 36,719 | 30,713 | 28,023 | 24,736 | 22,815 | 21,765 | 20,911 | 19,496 | 18,143 | 17,367 | 15,111 | 13,427 | 11,453 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||||||
16,926 | 15,734 | 14,898 | 13,905 | 13,015 | 12,632 | 11,443 | 11,149 | 10,587 | 10,066 | 9,796 | 8,841 | 8,925 | 8,391 | 7,959 | 7,255 | 6,930 | 5,947 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||||||
81,699 | 80,334 | 73,730 | 63,827 | 57,253 | 49,351 | 42,156 | 39,172 | 35,323 | 32,881 | 31,561 | 29,752 | 28,421 | 26,534 | 25,326 | 22,366 | 20,357 | 17,400 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||||
-81,699 | -80,334 | -73,730 | -63,827 | -54,875 | -45,463 | -36,785 | -32,540 | -29,590 | -27,676 | -26,592 | -24,895 | -23,670 | -21,906 | -20,360 | -17,476 | -13,413 | -11,315 | 0 | 0 | 0 |
Other income (expense): | ||||||||||||||||||||
Interest income | ||||||||||||||||||||
1,936 | 2,143 | 2,138 | 1,892 | 1,536 | 1,172 | 896 | 693 | 530 | 482 | 403 | 339 | 313 | 244 | 183 | 116 | 47 | 22 | 0 | 0 | 0 |
Other expense, net | ||||||||||||||||||||
-52 | -63 | -65 | -66 | -57 | -57 | -44 | -43 | -48 | -42 | -47 | -44 | -41 | -36 | -25 | 0 | 0 | - | 0 | - | - |
Total other income | ||||||||||||||||||||
1,884 | 2,080 | 2,073 | 1,826 | 1,479 | 1,115 | 852 | 650 | 482 | 440 | 356 | 295 | 272 | 208 | 158 | 99 | 39 | 20 | 0 | 0 | 0 |
Net loss | ||||||||||||||||||||
-79,815 | -78,254 | -71,657 | -62,001 | -53,396 | -44,348 | -35,933 | -31,890 | -29,108 | -27,236 | -26,236 | -24,600 | -23,398 | -21,698 | -20,202 | -17,377 | -13,374 | -11,295 | 0 | 0 | 0 |
Deemed dividend to convertible preferred stockholders | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 228 | 0 | 0 | 0 |
Net loss per share, basic and diluted | ||||||||||||||||||||
-0.57 | -0.65 | -0.66 | -0.55 | -0.59 | -0.64 | -0.54 | -0.46 | -0.49 | -0.38 | -0.48 | -0.47 | -0.47 | 5.81 | -0.47 | -0.46 | -7.10 | -6.49 | -5.57 | -2.44 | -4.71 |
Net loss attributable to common stockholders | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -11,523 | 0 | 0 | 0 |
Weighted-average common shares outstanding, basic and diluted | ||||||||||||||||||||
33,097 | 33,052 | 32,894 | 32,840 | 29,011 | 24,032 | 21,986 | 20,598 | 16,672 | 16,622 | 16,409 | 14,114 | 13,365 | 13,424 | 13,326 | 11,776 | 640 | 627 | 612 | 585 | 573 |