| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 |
|---|---|---|---|---|---|---|---|
Revenues: | |||||||
Total revenues | |||||||
335,001 | 207,742 | 181,227 | 1,535 | - | - | - | - |
Cost of goods sold: | |||||||
Product | |||||||
108,935 | 6,251 | - | - | - | - | - | - |
Amortization of intangibles | |||||||
36,401 | 1,517 | - | - | - | - | - | - |
Total cost of goods sold | |||||||
145,336 | 7,768 | - | - | - | - | - | - |
Operating expenses: | |||||||
Research and development | |||||||
322,969 | 291,007 | 230,893 | 115,785 | 43,016 | 23,263 | 8,902 | 5,632 |
Selling, general and administrative | |||||||
149,455 | 87,061 | 27,008 | 22,210 | 18,497 | 14,677 | 7,031 | 2,891 |
License expense | |||||||
3,529 | 67 | - | - | - | - | - | - |
Total operating expenses | |||||||
475,953 | 378,135 | 257,901 | 137,995 | 61,513 | 37,940 | 15,933 | 8,523 |
Operating loss | |||||||
-286,288 | -178,161 | -76,674 | -136,460 | -61,513 | -37,940 | -15,933 | -8,523 |
Other income (expense): | |||||||
Interest income (expense) | |||||||
792 | 6,154 | 2,799 | 901 | 510 | 206 | -704 | -1,644 |
Other income (expense) | |||||||
-794 | 81 | 204 | -188 | 287 | 700 | 1,050 | - |
Net loss before income taxes | |||||||
-286,290 | -171,926 | -73,671 | -135,747 | - | - | - | - |
Benefit from income taxes | |||||||
-6,631 | -28,338 | - | - | - | - | - | - |
Extinguishment of debt and other liabilities | |||||||
- | - | - | - | - | - | 2,420 | - |
Reimbursements from Aerpio | |||||||
- | - | - | - | - | - | - | 1,971 |
Net loss | |||||||
-279,659 | -143,588 | -73,671 | -135,747 | -60,716 | -37,034 | -13,167 | -8,196 |
Accretion on preferred stock | |||||||
- | - | - | - | - | 86,899 | 55,886 | 3,323 |
Net loss applicable to common stockholders - basic and diluted | |||||||
- | - | - | - | - | -123,933 | -69,053 | -11,519 |
Net loss per share - basic and diluted | |||||||
-2.36 | -2.47 | -1.69 | -3.60 | -2.29 | -8.04 | -126.94 | -27.82 |
Weighted-average number of common shares - basic and diluted | |||||||
118,395 | 58,038 | 43,500 | 37,716 | 26,469 | 15,406 | 544 | 414 |
Net loss | |||||||
-279,659 | -143,588 | -73,671 | -135,747 | -60,716 | -37,034 | -13,167 | -8,196 |
Other comprehensive gain - unrealized gain on debt securities | |||||||
261 | 181 | -400 | -42 | -234 | -56 | - | - |
Total comprehensive loss | |||||||
-279,398 | -143,407 | -74,071 | -135,789 | -60,950 | -37,090 | -13,167 | -8,196 |
Product Revenue, Net | |||||||
Total revenues | |||||||
111,119 | 6,824 | - | - | - | - | - | - |
License, Collaboration and Other Revenue | |||||||
Total revenues | |||||||
223,882 | 200,918 | 181,227 | 1,535 | - | - | - | - |