| Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 | Mar'13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating activities | |||||||||||||||||||||||||
Net loss | |||||||||||||||||||||||||
-58,411 | -117,934 | -80,089 | -60,920 | -68,389 | -87,031 | -54,357 | -59,565 | -74,629 | -100,328 | -48,891 | -35,134 | -38,866 | -33,363 | -26,165 | -26,997 | -17,655 | -14,653 | -6,942 | 28,646 | -7,401 | -5,395 | -3,875 | -5,909 | -5,147 | -5,682 |
Adjustments to reconcile net loss to net cash used in operating activities | |||||||||||||||||||||||||
Equity in net loss of unconsolidated entity | |||||||||||||||||||||||||
- | - | 0 | 0 | 0 | -222 | -180 | -184 | -130 | -149 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Depreciation and amortization | |||||||||||||||||||||||||
537 | 533 | 422 | 537 | 807 | 801 | 763 | 752 | 739 | 747 | 660 | 509 | 270 | 235 | 180 | 186 | 190 | 195 | 174 | 172 | 167 | 188 | 227 | 235 | 232 | 241 |
Loss on retirement of property and equipment | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | -2 | - | - | - | - | - | - | - | - |
Stock-based compensation | |||||||||||||||||||||||||
11,671 | 6,288 | 5,848 | 6,403 | 7,223 | 5,946 | 5,776 | 5,821 | 5,721 | 5,180 | 4,098 | 3,511 | 3,331 | 3,017 | 2,015 | 1,818 | 1,396 | 910 | 492 | 370 | 240 | 148 | 142 | 140 | 134 | 159 |
Accretion of discount on convertible notes | |||||||||||||||||||||||||
3,177 | 3,042 | 3,066 | 2,986 | 2,855 | 1,689 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Non-cash change in fair value of derivative liability | |||||||||||||||||||||||||
-125 | -975 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Other non-cash charges, net | |||||||||||||||||||||||||
983 | 729 | 768 | 914 | 855 | 605 | 324 | 143 | -121 | -179 | -185 | -157 | -45 | -20 | - | - | - | - | - | - | - | - | - | - | - | - |
Changes in operating assets and liabilities | |||||||||||||||||||||||||
Accounts receivable | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | -113 | 32 | 24 | -34 | -225 | 218 | -35 | -23 | 28 |
Prepaid expenses and other assets | |||||||||||||||||||||||||
7,214 | -3,652 | 797 | -998 | 360 | -3,733 | -6,576 | -3,631 | 1,394 | -28,553 | 17,110 | 14,555 | 169 | -460 | 278 | 2,980 | 2,322 | 4,164 | 113 | 2,928 | 2,881 | -726 | -90 | -1,343 | -319 | 699 |
Accounts payable | |||||||||||||||||||||||||
-7,649 | 6,392 | -6,913 | 160 | 2,710 | 5,316 | -14,907 | 2,675 | -504 | 10,341 | 4,520 | -1,883 | -2,070 | 4,921 | -3,006 | 5,379 | 138 | 305 | 227 | -987 | 966 | -518 | 1,101 | 480 | -1,318 | 40 |
Accrued liabilities | |||||||||||||||||||||||||
-596 | 23,205 | 6,389 | -892 | 2,080 | -4,163 | -210 | 1,777 | 4,993 | -6,194 | 4,554 | 3,178 | 2,668 | -2,557 | 607 | 2,537 | -146 | 1,275 | 491 | 895 | -255 | -296 | -1,104 | 882 | 942 | -578 |
Deferred rent | |||||||||||||||||||||||||
- | - | -8 | 15 | -7 | -3 | 41 | 31 | -32 | -26 | 361 | -16 | 42 | -14 | -28 | -33 | -35 | -32 | -17 | 114 | 116 | 63 | -9 | -37 | -42 | -41 |
Deferred revenue | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -6,323 | -38,703 | -4,603 | -4,695 | -4,493 | -4,646 | -4,580 | -4,534 |
Net cash used in operating activities | |||||||||||||||||||||||||
-59,298 | -74,576 | -72,850 | -51,474 | -52,431 | -74,095 | -55,526 | -44,837 | -64,855 | -61,399 | -51,532 | -44,139 | -36,735 | -27,281 | -26,667 | -20,083 | -18,434 | -16,049 | -12,041 | -12,445 | -13,617 | -9,554 | -8,139 | -7,474 | -9,397 | -11,122 |
Investing activities | |||||||||||||||||||||||||
Purchases of investments | |||||||||||||||||||||||||
0 | 64,022 | 0 | 35,764 | 71,828 | 415,203 | 61,718 | 215,488 | 0 | 28,334 | 31,845 | 78,413 | 49,047 | 6,566 | 5,129 | 160,750 | 7,000 | 12,750 | - | - | - | - | - | - | - | - |
Proceeds from maturities of investments | |||||||||||||||||||||||||
29,000 | 36,290 | 62,000 | 66,629 | 37,000 | 156,000 | 106,229 | 68,617 | 112,965 | 54,008 | 29,070 | 65,445 | 4,000 | 6,250 | 4,230 | 6,965 | 6,915 | 1,225 | - | - | - | - | 735 | 1,455 | 3,185 | 245 |
Proceeds from sales of investments | |||||||||||||||||||||||||
- | - | 0 | 0 | 0 | 83,184 | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 250 | - | - | - | - | - | - | - | - |
Purchases of property and equipment | |||||||||||||||||||||||||
736 | 303 | 1,799 | 1,060 | 65 | 212 | 54 | 470 | 677 | 849 | 1,057 | 2,609 | 2,022 | 931 | 501 | 76 | 271 | 375 | 241 | 96 | 292 | 20 | 78 | 23 | 43 | 49 |
Proceeds from sale of property and equipment | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 5 | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash provided by (used in) investing activities | |||||||||||||||||||||||||
28,264 | -28,035 | 60,201 | 29,805 | -34,893 | -176,231 | 44,457 | -147,190 | 112,288 | 24,825 | -3,832 | -15,577 | -47,069 | -1,242 | -1,400 | -153,861 | -356 | -11,650 | 720 | -97 | -10,337 | -20 | 657 | 1,551 | 3,142 | 196 |
Financing activities | |||||||||||||||||||||||||
Deferred offering costs | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | -36 | - | - | - | 756 | - | - | - | 0 |
Proceeds from issuance of 2025 convertible senior notes, net of offering costs | |||||||||||||||||||||||||
- | - | 0 | 0 | 0 | 277,656 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from issuance of convertible preferred stock, net of offering costs | |||||||||||||||||||||||||
- | - | 0 | 0 | 0 | 97,710 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from issuance of common stock, net of offering costs | |||||||||||||||||||||||||
-209 | 159,307 | - | - | - | - | - | - | - | - | - | - | - | - | 0 | -190 | 216,054 | 190,770 | - | - | - | - | - | - | - | - |
Proceeds from exercise of stock options and employee stock purchase plan | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 541 | 167 | 806 | 22 | - | - | - | - | - | - | - | - |
Proceeds from exercise of stock options | |||||||||||||||||||||||||
- | 430 | - | - | - | 20 | - | - | 643 | 71 | - | - | - | 45 | - | - | - | - | - | - | - | 34 | - | 0 | 0 | 16 |
Net cash provided by financing activities | |||||||||||||||||||||||||
762 | 159,737 | 1,104 | 325 | 1,122 | 375,386 | 631 | 161,572 | 643 | 71 | 948 | 312 | 135,805 | 45 | 541 | -23 | 216,860 | 190,828 | 589 | -154 | 81,269 | -722 | 32 | 0 | 0 | 16 |
Effect of exchange rate changes on cash, cash equivalents and restricted cash | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 21 | 11 | 8 | -14 | -14 | -26 | -8 | 4 | 7 | 13 | 6 | -4 | -3 |
Net increase in cash, cash equivalents and restricted cash | |||||||||||||||||||||||||
-30,272 | 57,126 | -11,545 | -21,344 | -86,202 | 125,060 | -10,438 | -30,455 | 48,076 | -36,503 | -54,416 | -59,404 | 52,001 | -28,457 | -27,515 | -173,959 | 198,056 | 163,115 | -10,758 | -12,704 | 57,319 | -10,289 | -7,437 | -5,917 | -6,259 | -10,913 |
Supplemental disclosures: | |||||||||||||||||||||||||
Cash paid for interest | |||||||||||||||||||||||||
0 | 3,594 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Offering costs included in accounts payable and accrued liabilities | |||||||||||||||||||||||||
- | 265 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 94 | 25 | - | -160 | -308 | 560 | - | - | - | - |
Purchases of property and equipment included in accounts payable and accrued liabilities | |||||||||||||||||||||||||
55 | 188 | -341 | 304 | 224 | 22 | -132 | 39 | 0 | 101 | 69 | -722 | 968 | 188 | - | - | - | - | - | - | - | - | - | - | - | - |