| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||||
Net loss | ||||||||
-40,019 | -30,527 | -31,738 | -24,560 | -18,560 | -17,373 | -15,317 | -11,121 | -8,437 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation and amortization | ||||||||
1,446 | 1,378 | 1,278 | 821 | 298 | 276 | 279 | 252 | 212 |
Stock-based compensation | ||||||||
6,642 | 5,238 | 4,104 | 3,694 | 3,245 | 2,660 | 1,980 | 1,161 | 1,124 |
Accretion of discount on marketable securities | ||||||||
240 | 674 | 1,170 | 1,536 | 1,321 | 967 | 825 | 601 | 352 |
Amortization of right-of-use assets | ||||||||
297 | - | - | - | 768 | - | - | - | - |
Loss from disposal of property and equipment, net | ||||||||
-9 | - | - | - | - | -62 | 0 | -13 | -76 |
Changes in operating assets and liabilities: | ||||||||
Accounts receivable | ||||||||
- | - | - | - | - | - | 0 | -169 | -69 |
Prepaid expenses and other current assets | ||||||||
3,305 | 327 | 373 | -1,855 | 2,751 | -1,393 | 2,002 | 585 | 1,051 |
Other assets | ||||||||
284 | -30 | 89 | 0 | -17 | 26 | 21 | -153 | 0 |
Accounts payable | ||||||||
3,135 | 20 | -282 | -269 | 683 | -205 | 226 | -47 | -783 |
Accrued liabilities and accrued clinical supply costs | ||||||||
7,805 | 1,743 | 1,624 | 6,795 | -952 | 5,868 | -176 | 667 | -1,616 |
Deferred revenue | ||||||||
-7,171 | -6,001 | -2,696 | -6,917 | -5,605 | -9,145 | -6,503 | -7,109 | 195,249 |
Deferred rent | ||||||||
- | 0 | 0 | 0 | -44 | -6 | 0 | 0 | -1 |
Lease liabilities | ||||||||
-628 | - | - | - | 656 | - | - | - | - |
Lease liabilities and other long-term liabilities | ||||||||
- | - | - | - | - | - | 0 | 0 | 35 |
Net cash used in operating activities | ||||||||
-32,313 | -28,827 | -28,863 | -18,052 | -23,566 | -17,654 | -22,359 | -17,048 | 184,525 |
Cash flows from investing activities: | ||||||||
Purchase of property and equipment | ||||||||
3,566 | 1,573 | 2,299 | 9,363 | 2,030 | 417 | 157 | 697 | 613 |
Purchase of marketable securities | ||||||||
202,906 | 118,370 | 71,792 | 72,215 | 267,232 | 77,118 | 126,789 | 89,426 | 178,902 |
Maturities of marketable securities | ||||||||
81,600 | 150,000 | 120,000 | 108,000 | 118,000 | 120,000 | 80,000 | 50,000 | 0 |
Net cash used in investing activities | ||||||||
-124,872 | 30,057 | 45,909 | 26,422 | -151,262 | 42,465 | -46,946 | -40,123 | -179,515 |
Cash flows from financing activities: | ||||||||
Proceeds from issuance of common stock upon initial public offering, net of issuance costs | ||||||||
225,244 | -340,256 | 0 | 340,435 | -170,307 | 2,182 | -278 | 0 | 0 |
Payment of convertible preferred stock issuance costs | ||||||||
- | - | - | - | - | - | - | - | 62 |
Proceeds from the exercise of options to purchase common stock | ||||||||
3,217 | 731 | 720 | 63 | 5 | - | - | - | - |
Net cash provided by financing activities | ||||||||
228,461 | 1,437 | 720 | -116 | 170,312 | -1,280 | 62,334 | 70,154 | -62 |
Net increase in cash, cash equivalents, and restricted cash | ||||||||
71,276 | 2,667 | 17,766 | 8,254 | -4,516 | 23,531 | -6,971 | 12,983 | 4,948 |
Non-cash investing and financing activities: | ||||||||
Property and equipment purchases included in accounts payable and accrued liabilities | ||||||||
178 | -204 | 826 | 1,778 | 1,071 | 263 | 22 | -101 | 109 |
Issuance costs for convertible preferred stock included in accounts payable | ||||||||
- | - | - | - | - | - | - | -30 | 33 |
Deferred offering costs in accounts payable and accrued liabilities | ||||||||
641 | - | - | - | 179 | - | - | - | - |
Tenant improvements paid by landlord | ||||||||
- | 0 | 0 | 0 | 8,286 | 7,048 | 401 | 0 | 0 |