| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||||||||
Net loss | ||||||||||||
-43,505 | -47,339 | -45,591 | -41,813 | -39,187 | -35,648 | 0 | 0 | 0 | - | - | - | - |
Net loss | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||
Stock-based compensation expense | ||||||||||||
3,395 | 2,989 | 2,748 | 2,533 | 2,274 | 2,049 | 1,734 | 1,238 | 825 | 517 | 0 | 0 | 0 |
Depreciation expense | ||||||||||||
164 | 163 | 155 | 130 | 99 | 78 | 64 | 66 | 75 | 73 | 0 | 0 | 0 |
Non-cash interest expense | ||||||||||||
8 | 8 | 8 | 8 | 88 | 161 | 246 | 345 | 339 | 351 | 0 | 0 | 0 |
Amortization of operating lease assets | ||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - |
Non-cash lease expense | ||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Amortization of premium on investments | ||||||||||||
- | - | - | - | - | - | - | - | - | 33 | 0 | 0 | 0 |
Change in fair value of warrant liability | ||||||||||||
- | - | - | - | - | - | - | - | - | 257 | 0 | 0 | 0 |
Changes in assets and liabilities: | ||||||||||||
Prepaid expenses and other current assets | ||||||||||||
1,000 | 202 | -18 | 2,815 | 389 | 1,287 | 1,601 | 561 | 441 | 984 | 0 | 0 | 0 |
Other assets | ||||||||||||
- | -123 | -191 | -96 | 136 | 34 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||||||
-871 | 972 | 1,976 | 1,383 | 446 | 441 | 48 | -337 | 824 | 199 | 0 | 0 | 0 |
Accrued expenses | ||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Accrued expenses | ||||||||||||
- | - | - | - | - | - | - | 0 | 436 | - | 0 | 0 | 0 |
Operating lease liabilities | ||||||||||||
-496 | -531 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Other liabilities | ||||||||||||
- | - | - | - | - | 20 | 0 | 0 | 0 | - | - | - | - |
Net cash used in operating activities | ||||||||||||
-42,380 | -43,632 | -40,417 | -39,556 | -34,753 | -31,839 | 0 | 0 | 0 | - | - | - | - |
Cash flows from investing activities: | ||||||||||||
Net cash used in operating activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Purchases of property and equipment | ||||||||||||
- | 122 | 284 | 304 | 371 | 318 | 157 | 116 | 37 | 57 | 0 | 0 | 0 |
Maturities of investments | ||||||||||||
- | - | - | - | - | - | - | - | - | 24,721 | 0 | 0 | 0 |
Net cash (used in) provided by investing activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Net cash used in investing activities | ||||||||||||
- | -122 | -284 | -304 | -371 | -318 | 0 | 0 | 0 | - | - | - | - |
Proceeds from exercise of stock options | ||||||||||||
33 | 36 | 71 | 71 | 151 | 139 | 110 | 107 | 27 | 28 | 0 | 0 | 0 |
Repayment of loan payable | ||||||||||||
0 | - | - | - | - | 10,492 | 0 | 0 | 0 | - | - | - | - |
Payments of common stock offering costs | ||||||||||||
- | - | - | - | - | - | - | - | 0 | - | - | - | - |
Other | ||||||||||||
-30 | -29 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net cash (used in) provided by financing activities | ||||||||||||
11,114 | 12,118 | 9,561 | 9,530 | 497 | -694 | 0 | 0 | 0 | - | - | - | - |
Net decrease in cash and cash equivalents | ||||||||||||
-31,304 | -31,636 | -31,140 | -30,330 | -34,627 | -32,851 | 0 | 0 | 0 | - | - | - | - |
Supplemental disclosures: | ||||||||||||
Net cash (used in) provided by financing activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Net (decrease) increase in cash and cash equivalents | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Right-of-use assets obtained in exchange of operating lease obligations | ||||||||||||
- | 992 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Accretion of convertible preferred stock to redemption value | ||||||||||||
- | - | - | - | - | - | - | - | - | 58 | 0 | 0 | 0 |