| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | ||
|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||
Net loss | ||||||
-29,369 | -31,547 | -22,604 | - | - | ||
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Depreciation and amortization expense | ||||||
155 | 218 | 129 | 232 | 325 | ||
Net amortization of premiums and discounts on investments | ||||||
231 | 253 | 152 | - | - | ||
Net loss | ||||||
- | - | - | -18,123 | -12,878 | ||
Stock-based compensation expense | ||||||
2,116 | 3,280 | 1,749 | 688 | 626 | ||
Change in deferred rent | ||||||
- | 11 | 11 | 18 | 21 | ||
Gain on sale of property and equipment | ||||||
-5 | - | - | -12 | - | ||
Write-off of deferred offering costs | ||||||
- | - | - | 1,500 | - | ||
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
206 | 117 | 764 | 75 | 109 | ||
Other assets | ||||||
-1,318 | -15 | - | - | - | ||
Other assets | ||||||
- | - | -147 | 778 | - | ||
Accounts payable | ||||||
-277 | 130 | -241 | 1,215 | -237 | ||
Operating lease liabilities | ||||||
-370 | - | - | - | - | ||
Accrued expenses and other current liabilities | ||||||
385 | 359 | 1,216 | 333 | 584 | ||
Net cash used in operating activities | ||||||
-26,474 | -27,926 | -20,531 | - | - | ||
Cash flows from investing activities: | ||||||
Net cash used in operating activities | ||||||
- | - | - | -15,014 | -11,710 | ||
Purchases of property and equipment | ||||||
151 | 4,423 | 142 | - | 94 | ||
Purchases of investments | ||||||
27,237 | 31,194 | 71,056 | 12,634 | 2,368 | ||
Proceeds from sales or maturities of investments | ||||||
24,574 | 60,305 | 32,286 | 12,634 | 12,378 | ||
Net cash provided by (used in) investing activities | ||||||
-2,814 | 24,688 | -38,912 | - | - | ||
Cash flows from financing activities: | ||||||
Proceeds from issuance of common stock, common warrants and pre-funded warrants, net of issuance costs | ||||||
23,799 | - | - | - | - | ||
Proceeds from exercise of stock options | ||||||
165 | 42 | 111 | 23 | 52 | ||
Increase in construction financing liability | ||||||
- | 2,473 | - | - | - | ||
Proceeds from initial public offering of common stock, net of commissions and underwriting discounts | ||||||
- | - | 52,313 | - | - | ||
Payments of initial public offering costs | ||||||
- | - | 2,304 | 180 | 1,320 | ||
Changes in restricted cash | ||||||
- | - | - | 25 | -713 | ||
Net cash provided by (used in) investing activities | ||||||
- | - | - | -25 | 10,629 | ||
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs | ||||||
- | - | 471 | 32,143 | -91 | ||
Net cash provided by financing activities | ||||||
23,964 | 2,515 | 50,591 | - | - | ||
Net cash provided by financing activities | ||||||
- | - | - | 31,986 | -1,359 | ||
Net decrease in cash, cash equivalents and restricted cash | ||||||
-5,324 | -723 | -8,852 | - | - | ||
Net increase (decrease) in cash and cash equivalents | ||||||
- | - | - | 16,947 | -2,440 | ||
Supplemental disclosure of non-cash financing activities: | ||||||
Accretion of redeemable convertible preferred stock to redemption value | ||||||
- | - | 41 | 75 | 71 | ||
Issuance costs for redeemable convertible preferred stock included in accounts payable and accrued expenses | ||||||
- | - | - | 154 | - | ||
Deferred offering costs included in accounts payable and accrued expenses | ||||||
- | - | - | - | 180 | ||
Capitalization of build-to-suit asset | ||||||
- | 2,869 | - | - | - | ||