| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 |
|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | |||||||||||
Net Income (Loss) Attributable to Parent | |||||||||||
2,404,300 | 77,600 | 443,300 | 399,400 | 144,400 | 657,000 | 252,895 | 254,822 | 175,315 | 97,030 | 295,166 | 33,149 |
Adjustments to reconcile net income to net cash flows from operating activities: | |||||||||||
Depreciation and amortization | |||||||||||
376,800 | 405,300 | 496,700 | 396,400 | 166,600 | 47,000 | 28,693 | 23,887 | 17,616 | 15,792 | 12,473 | 7,608 |
Impairment of assets | |||||||||||
0 | 13,500 | 118,800 | 85,000 | 0 | - | - | - | - | - | - | - |
Impairment of intangible assets | |||||||||||
- | - | - | - | - | 12,000 | 33,521 | 26,300 | 0 | 0 | - | - |
Change in fair value of contingent consideration | |||||||||||
11,600 | 116,500 | 41,000 | 35,700 | 64,200 | 20,000 | 4,006 | 6,550 | 1,400 | 0 | 0 | - |
Payments on facility lease obligation | |||||||||||
- | - | - | - | - | - | - | - | - | - | 301 | 273 |
Payments of contingent consideration | |||||||||||
100,000 | 0 | 18,000 | 0 | 0 | - | - | - | - | - | - | - |
Share-based compensation expense | |||||||||||
237,000 | 203,000 | 243,100 | 192,300 | 227,100 | 114,000 | 76,203 | 54,013 | 44,763 | 32,338 | 28,731 | 23,682 |
Non-cash expense for acquired IPR&D | |||||||||||
0 | 64,600 | 0 | 0 | - | - | - | - | - | - | - | - |
Premium amortization of available-for-sale securities | |||||||||||
- | - | - | - | - | - | -3,235 | 0 | 24 | - | - | - |
Deferred taxes (benefit) | |||||||||||
-455,400 | 32,900 | -45,900 | 104,300 | 395,500 | -154,000 | 92,831 | 71,155 | 42,066 | 36,389 | -208,726 | - |
Unrealized foreign currency loss | |||||||||||
2,100 | -4,800 | 9,400 | -6,900 | - | - | - | - | -5,516 | 523 | 997 | -3 |
Unrealized (gain) loss on forward contracts | |||||||||||
16,500 | 15,800 | -11,100 | 3,600 | - | - | - | - | -479 | -6,205 | 2,233 | 473 |
Unrealized Gain (Loss) on Investments | |||||||||||
26,900 | 40,200 | 0 | 0 | - | - | - | - | - | - | - | - |
Gain on sale of strategic equity investments | |||||||||||
32,800 | 0 | 0 | - | - | - | - | - | - | - | - | - |
Gain on modification of purchase option | |||||||||||
32,000 | 0 | 0 | - | - | - | - | - | - | - | - | - |
Change in excess tax benefit from stock options | |||||||||||
- | - | - | - | -89,700 | 251,000 | 105,714 | 7,228 | - | - | - | - |
Marketable securities premium amortization | |||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | - |
Non-cash debt exchange expense | |||||||||||
- | - | - | - | - | - | - | - | - | - | 3,395 | - |
Loss on disposal of property, plant and equipment | |||||||||||
- | - | - | - | - | - | - | - | - | - | -271 | -44 |
Other | |||||||||||
2,700 | 2,000 | -5,400 | -6,500 | -2,900 | -37,000 | -2,040 | 4,833 | -136 | -1,036 | - | - |
Changes in operating assets and liabilities, excluding the effect of acquisitions: | |||||||||||
Accounts receivable | |||||||||||
319,200 | 208,800 | 55,200 | 122,100 | 115,800 | 28,000 | 116,439 | 72,870 | 78,778 | 59,239 | 36,440 | 31,262 |
Inventories | |||||||||||
156,900 | 14,700 | 88,200 | 83,800 | 88,400 | 67,000 | -126 | 6,265 | 12,179 | 14,119 | -14,596 | 15,700 |
Prepaid expenses, right of use operating assets and other assets | |||||||||||
31,000 | 155,600 | 137,200 | 97,500 | 57,200 | 18,000 | 39,879 | 17,041 | 21,040 | 2,773 | 6,926 | -951 |
Accounts payable, accrued expenses, lease liabilities and other liabilities | |||||||||||
230,700 | -55,100 | 110,100 | 166,800 | -115,900 | 265,000 | 242,355 | 68,951 | 79,781 | 47,455 | 14,131 | 32,912 |
Deferred revenue | |||||||||||
- | - | - | - | -37,900 | 6,000 | 23,476 | 13,172 | 15,033 | 1,315 | 400 | 1,339 |
Net cash provided by operating activities | |||||||||||
2,084,900 | 426,000 | 1,115,600 | 1,086,300 | 675,200 | 640,000 | 497,349 | 410,613 | 270,084 | 160,906 | 113,841 | 53,199 |
Cash flows from investing activities: | |||||||||||
Purchases of available-for-sale debt securities | |||||||||||
80,200 | 782,700 | 1,648,800 | 667,100 | 519,700 | 664,000 | 1,048,429 | 0 | 0 | - | - | - |
Proceeds from maturity or sale of available-for-sale debt securities | |||||||||||
222,200 | 1,473,500 | 1,089,900 | 717,800 | 1,159,500 | 620,000 | 60,917 | 0 | 94,458 | - | - | - |
Purchases of mutual funds related to nonqualified deferred compensation plan | |||||||||||
17,600 | 12,100 | 9,900 | 8,500 | 15,000 | 3,000 | 985 | 0 | 0 | 129,860 | 19,026 | - |
Proceeds from sale of mutual funds related to nonqualified deferred compensation plan | |||||||||||
14,700 | 12,300 | 7,700 | 4,000 | 10,200 | 0 | 0 | - | - | 53,387 | 0 | 9,368 |
Purchases of property, plant and equipment | |||||||||||
154,700 | 213,000 | 357,300 | 332,700 | 286,300 | 137,000 | 29,329 | 21,846 | 21,982 | 12,843 | 35,275 | 39,733 |
Payment for acquisition of business, net of cash acquired | |||||||||||
- | - | - | - | 3,939,300 | 0 | 0 | 605,735 | 105,886 | 0 | 0 | - |
Payments to Acquire Other Investments | |||||||||||
73,300 | 10,300 | 0 | 0 | - | 38,000 | 0 | 0 | - | - | - | - |
Proceeds from sale of strategic equity investments | |||||||||||
114,700 | 0 | 0 | - | - | - | - | - | - | - | - | - |
Purchase of intangible assets | |||||||||||
16,000 | 0 | 0 | - | - | - | - | - | - | - | 27,740 | 8,624 |
Other | |||||||||||
100 | -2,800 | -100 | 1,100 | -5,400 | 1,000 | 9,315 | 4 | 307 | - | - | - |
Increase in restricted cash | |||||||||||
- | - | - | - | - | - | - | - | - | 2 | -618 | -339 |
Net cash (used in) provided by investing activities | |||||||||||
9,700 | 470,500 | -918,300 | -287,600 | -3,585,200 | -223,000 | -1,027,141 | -627,585 | -33,717 | -89,318 | -81,423 | -38,650 |
Cash flows from financing activities: | |||||||||||
Proceeds from term loan | |||||||||||
- | - | - | - | 3,500,000 | 0 | 0 | 240,000 | 0 | 0 | - | - |
Payments on term loan | |||||||||||
98,000 | 293,800 | 175,000 | 375,000 | 101,200 | 55,000 | 36,000 | 91,000 | 0 | 0 | - | - |
Debt issuance costs | |||||||||||
- | - | - | - | 45,500 | 0 | 0 | 6,184 | 0 | 0 | 50 | 312 |
Proceeds from revolving credit facility | |||||||||||
0 | 250,000 | 0 | 0 | 200,000 | 0 | 0 | 115,000 | 60,000 | 0 | 0 | - |
Payments on revolving credit facility | |||||||||||
250,000 | - | - | - | 200,000 | 0 | 0 | 115,000 | 60,000 | 0 | 0 | - |
Payments on mortgage loan | |||||||||||
- | - | - | - | - | - | - | - | - | - | 44,000 | - |
Change in excess tax benefit from stock options | |||||||||||
- | - | - | - | -89,700 | 251,000 | 105,714 | 7,228 | 4,016 | 1,970 | 764 | - |
Repurchases of common stock | |||||||||||
416,000 | 85,000 | 463,600 | 430,600 | 327,700 | 303,000 | 66,136 | 11,553 | 0 | 0 | - | - |
Payment of taxes in exchange of treasury shares | |||||||||||
- | - | - | - | - | - | - | - | - | - | 1,416 | - |
Net proceeds from issuance of common stock | |||||||||||
- | - | - | - | - | - | - | 462,212 | 0 | 0 | 30,733 | 28,893 |
Net proceeds from issuance of common stock under share-based compensation arrangements | |||||||||||
29,900 | 47,300 | 85,900 | 37,100 | 82,000 | 114,000 | 71,281 | 66,438 | 35,765 | 37,546 | - | - |
Equity issuance costs for shares issued in connection with acquisition of business | |||||||||||
- | - | - | - | - | 0 | 0 | - | - | - | - | - |
Payment for Contingent Consideration | |||||||||||
0 | 0 | 7,000 | 60,000 | 50,000 | 0 | 3,000 | 0 | 0 | - | - | - |
Repayment of development-related grants | |||||||||||
0 | 0 | 26,000 | 0 | 26,000 | 0 | 0 | - | - | - | - | - |
Other | |||||||||||
-5,000 | -20,900 | -10,900 | -7,700 | -8,800 | 0 | -220 | -765 | -731 | -649 | - | - |
Net cash used in financing activities | |||||||||||
-739,100 | -102,400 | -596,600 | -836,200 | 2,985,100 | 7,000 | 71,639 | 666,376 | 39,050 | 38,867 | -14,270 | 28,308 |
Effect of exchange rate changes on cash and cash equivalents and restricted cash | |||||||||||
800 | -11,200 | 17,700 | -6,600 | -9,000 | -10,000 | -1,491 | -768 | -1,697 | -482 | 1,012 | -166 |
Net change in cash and cash equivalents and restricted cash | |||||||||||
1,356,300 | 782,900 | -381,600 | -44,100 | 66,100 | 414,000 | -459,644 | 448,636 | 273,720 | 109,973 | 19,160 | 42,691 |
Cash paid for interest (net of amounts capitalized) | |||||||||||
72,600 | 90,900 | 95,300 | 79,600 | 41,400 | 2,000 | 2,831 | 4,475 | 538 | 500 | 4,282 | 6,688 |
Cash paid for income taxes | |||||||||||
187,900 | 163,900 | 162,100 | 37,700 | 123,200 | 91,000 | 76,165 | 18,272 | 10,221 | 7,953 | 4,268 | - |
Fair value of strategic investment and purchase option | |||||||||||
75,000 | 0 | 0 | - | - | - | - | - | - | - | - | - |
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability | |||||||||||
27,500 | 0 | 0 | - | - | - | - | - | - | - | - | - |
Common stock issued in acquisition of business | |||||||||||
- | - | - | - | 4,917,800 | 0 | 0 | - | - | 6,249 | 88,409 | - |
Contingent consideration issued in acquisitions | |||||||||||
- | - | - | - | - | - | - | 117,000 | 16,720 | 0 | 0 | - |
Capitalization of construction costs related to facility lease obligations | |||||||||||
0 | 44,800 | 121,800 | 103,100 | 41,000 | 75,000 | 32,230 | 0 | 0 | - | 722 | - |
Accounts payable and accrued expenses for purchases of property, plant and equipment and intangible assets | |||||||||||
13,300 | 21,400 | 34,700 | 23,500 | 30,100 | 17,000 | 0 | 0 | - | - | - | - |