| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|---|
Revenues | |||||||||
50,713 | 60,854 | - | - | - | - | - | - | - | - |
Grant and royalty revenue | |||||||||
- | - | - | - | - | 631 | 1,484 | 989 | 1,617 | 1,803 |
Research and development revenue under collaborative agreements | |||||||||
- | - | - | - | - | 4,448 | 6,502 | 5,698 | 7,768 | 6,032 |
Revenues | |||||||||
- | - | 64,310 | 64,650 | 67,790 | 5,080 | 7,986 | 6,688 | 9,386 | 7,835 |
Cost of sales | |||||||||
25,038 | 27,660 | 24,578 | 25,255 | 20,510 | - | - | - | - | - |
Gross margin | |||||||||
25,675 | 33,194 | 39,732 | 39,395 | 47,280 | - | - | - | - | - |
Operating expenses: | |||||||||
Sales and marketing | |||||||||
28,730 | 32,831 | 32,910 | 31,533 | 36,167 | - | - | - | - | - |
General and administrative | |||||||||
13,588 | 13,436 | 13,722 | 13,625 | 11,412 | 4,758 | 4,234 | 4,091 | 3,370 | 4,504 |
Research and development | |||||||||
10,384 | 12,176 | 8,299 | 7,805 | 9,558 | 18,126 | 11,343 | 8,158 | 9,726 | 7,819 |
Amortization of intangible assets | |||||||||
2,095 | 7,074 | 7,240 | 7,193 | 6,826 | - | - | - | - | - |
Settlement gain | |||||||||
5,609 | 0 | - | - | - | - | - | - | - | - |
Loss on divestiture | |||||||||
0 | -7,770 | 0 | - | - | - | - | - | - | - |
Total operating expenses | |||||||||
49,188 | 73,287 | 62,171 | 60,156 | 63,963 | 22,885 | 15,578 | 12,249 | 13,096 | 12,324 |
Loss from operations | |||||||||
-23,513 | -40,093 | -22,439 | -20,761 | -16,683 | -17,805 | -7,591 | -5,561 | -3,710 | -4,488 |
Other expenses: | |||||||||
Interest expense, net | |||||||||
4,052 | 4,063 | 4,508 | 18,168 | 10,036 | - | - | - | - | - |
Other expense (income), net | |||||||||
408 | -1,440 | - | - | - | 0 | 26 | -90 | -4 | -13 |
Other expense | |||||||||
- | - | 41 | 1,851 | 663 | - | - | - | - | - |
Net loss before income taxes | |||||||||
-27,157 | -45,596 | -26,988 | -40,780 | -27,382 | - | - | - | - | - |
Income tax expense | |||||||||
275 | 191 | 304 | 387 | 49 | - | - | - | - | - |
Net loss | |||||||||
-27,432 | -45,787 | -27,292 | -41,167 | -27,431 | - | - | - | - | - |
Current dividends on convertible preferred stock | |||||||||
- | - | - | - | 8,951 | - | - | - | - | - |
Change in fair value of warrants | |||||||||
- | - | - | - | - | -1,250 | - | - | - | - |
Change in fair value of warrants | |||||||||
- | - | - | - | - | - | 1,000 | 2,900 | 600 | -100 |
Total other income (expense), net | |||||||||
- | - | - | - | - | - | 1,026 | 2,809 | 595 | -113 |
Net loss attributable to common stockholders | |||||||||
- | - | - | - | -36,382 | -16,555 | -6,564 | -2,752 | -3,114 | -4,602 |
Other comprehensive income (loss): | |||||||||
Foreign currency translation | |||||||||
-871 | 706 | 324 | 1,463 | 26 | - | - | - | - | - |
Comprehensive loss | |||||||||
-28,303 | -45,081 | -26,968 | -39,704 | -27,405 | - | - | - | - | - |
Net loss per share, basic and diluted (USD per share) | |||||||||
-1.27 | -2.31 | -2.01 | -105.69 | -151.90 | -1.00 | -0.49 | -0.26 | -0.35 | -0.08 |
Shares used in computing net loss per share, basic and diluted (shares) | |||||||||
21,542 | 19,789 | 13,565 | 389 | 239 | 16,555 | 13,438 | 10,736 | 8,996 | - |
Basic (in shares) | |||||||||
- | - | - | - | - | - | - | - | - | 55,765 |
Diluted (in shares) | |||||||||
- | - | - | - | - | - | - | - | - | 55,765 |