| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues | ||||||||||
Grant revenue | ||||||||||
375 | 0 | - | - | - | - | - | - | - | - | - |
Total revenues | ||||||||||
375 | 0 | - | - | - | - | - | - | - | - | - |
License fee revenue | ||||||||||
- | - | - | - | 3,600 | 8,454 | 941 | 4,276 | 877 | 40 | 2,681 |
Royalty revenue | ||||||||||
- | - | - | - | 650 | 36 | 0 | 0 | - | - | - |
Grant revenue | ||||||||||
- | - | - | - | - | - | - | - | 483 | - | - |
Product sales | ||||||||||
- | - | - | - | 589 | 769 | 21 | 23 | 0 | 527 | 10 |
Contract service revenue | ||||||||||
- | - | - | - | - | 0 | 1,549 | 3,646 | 2,243 | 4,406 | 281 |
Total revenue | ||||||||||
- | - | - | - | 4,839 | 9,259 | 2,511 | 7,945 | 3,603 | 4,973 | 2,973 |
Cost of goods sold | ||||||||||
- | - | - | - | 922 | 918 | 23 | 10 | 0 | 386 | 4 |
Cost of Sandoz rights | ||||||||||
- | - | - | - | 0 | 0 | 2,608 | 4,230 | 1,858 | 3,557 | 123 |
Gross profit | ||||||||||
- | - | - | - | 3,917 | 8,341 | -120 | 3,705 | 1,745 | 1,030 | 2,845 |
Operating expense | ||||||||||
Research and development | ||||||||||
22,563 | 553 | 3,463 | 5,880 | 14,649 | 21,288 | 5,123 | 5,375 | 5,821 | 2,110 | 1,883 |
General and administrative | ||||||||||
7,559 | 2,631 | 7,210 | 7,778 | 10,516 | 11,418 | 13,554 | 15,336 | 11,451 | 10,153 | 4,196 |
Gain on contract settlement | ||||||||||
- | - | - | - | - | 900 | 534 | 0 | 0 | - | - |
Recovery loss on sale of subsidiary | ||||||||||
- | - | - | - | - | 50 | 255 | 250 | -2,760 | - | - |
Deconsolidation of former French Subsidiaries | ||||||||||
- | - | - | - | - | 846 | 641 | 0 | 0 | - | - |
Loss on disposal of assets | ||||||||||
- | - | -2 | -14 | -102 | 0 | 0 | - | - | - | - |
Impairment on goodwill and intangible assets | ||||||||||
- | - | - | - | - | - | - | 8,254 | 0 | 10,168 | - |
Acquisiton costs | ||||||||||
- | - | - | - | - | - | - | - | - | - | 585 |
Total operating expense | ||||||||||
30,122 | 3,184 | 10,675 | 13,672 | 25,267 | 30,900 | 17,247 | 28,715 | 20,032 | 22,431 | 6,665 |
Loss before other expense | ||||||||||
-29,747 | -3,184 | -10,675 | -13,672 | -21,350 | -22,559 | -17,367 | -25,010 | -18,287 | -21,401 | -3,819 |
Other income (expense) | ||||||||||
Interest income | ||||||||||
151 | 0 | - | - | - | - | - | - | - | - | - |
Interest income | ||||||||||
- | - | - | - | - | - | - | - | - | - | 25 |
Interest expense | ||||||||||
29 | 131 | - | - | - | - | - | - | - | - | 28,696 |
Interest expense | ||||||||||
- | - | -83 | -983 | -895 | -339 | -727 | -325 | -364 | -8,822 | - |
Loss on warrant issuance | ||||||||||
5,020 | 0 | 0 | 461 | 0 | - | - | - | - | - | - |
Gain on sale of investment | ||||||||||
- | - | - | - | - | 0 | 2,600 | 0 | 0 | - | - |
Change in fair value of warrant liabilities | ||||||||||
16,501 | 0 | 646 | -7,479 | -3,236 | 0 | 0 | - | - | - | - |
Change in fair value of convertible notes payable | ||||||||||
-109 | -160 | - | - | - | - | - | - | - | - | - |
Loss on extinguishment of debt | ||||||||||
- | - | -422 | 0 | - | -82 | 0 | 0 | - | - | - |
Rental income | ||||||||||
- | - | - | - | - | - | - | - | - | 415 | - |
Other income, net | ||||||||||
- | - | 77 | -22 | -14 | 503 | -376 | 175 | 426 | 300 | 10 |
Total other income (expense) | ||||||||||
-21,508 | -291 | -1,074 | 6,013 | 2,327 | 82 | 1,497 | -150 | 62 | -8,107 | -28,660 |
Loss from continuing operations | ||||||||||
- | - | -11,749 | -7,659 | - | -22,477 | -15,870 | -25,676 | -18,225 | -29,508 | - |
(Loss) income from discontinued operations | ||||||||||
- | - | 12,070 | 226 | - | - | - | - | - | - | - |
Loss from continuing operations before income tax expense | ||||||||||
- | - | - | - | - | - | - | -25,160 | -18,225 | - | - |
Loss from continuing operations before income taxes | ||||||||||
- | - | - | - | - | - | - | - | - | -29,508 | -32,480 |
Income tax expense | ||||||||||
- | - | - | - | - | - | - | 516 | 0 | - | -437 |
Income (loss) from discontinued operations | ||||||||||
- | - | - | - | - | 691 | -1,068 | -6,095 | 108 | - | - |
Net loss and comprehensive loss | ||||||||||
-51,255 | -3,475 | 321 | -7,433 | -19,023 | -21,786 | -16,938 | -31,771 | -18,117 | -29,508 | -32,042 |
Continuing operations (in usd per share) | ||||||||||
- | - | -29.64 | -1.18 | - | -0.57 | -0.46 | -0.94 | -0.91 | -2.49 | - |
Discontinued operations (in usd per share) | ||||||||||
- | - | 30.45 | - | - | - | - | - | - | - | - |
Discontinued operations (USD per share) | ||||||||||
- | - | - | 0.03 | - | 0.02 | -0.03 | -0.22 | 0.01 | - | - |
Net loss per share basic and diluted | ||||||||||
-2.52 | -1.13 | 0.81 | -1.15 | -3.83 | -0.55 | -0.49 | -1.16 | -0.90 | -2.49 | -5.43 |
Weighted average common shares outstanding basic and diluted loss | ||||||||||
20,308 | 3,081 | 396 | 6,517 | 4,972 | 39,540 | 34,413 | 27,458 | 20,023 | 11,847,703 | - |
Net loss | ||||||||||
-51,255 | -3,475 | 321 | -7,433 | - | - | - | -31,771 | -18,117 | -29,508 | -32,042 |
Foreign currency translation adjustments | ||||||||||
- | - | - | - | - | - | - | 641 | 0 | - | - |
Comprehensive loss | ||||||||||
- | - | - | - | - | - | - | -31,130 | -18,117 | -29,508 | - |
Weighted average common shares outstanding used for basic and diluted net loss per share | ||||||||||
- | - | - | - | - | - | - | - | - | - | 5,906 |