| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 |
|---|---|---|---|---|---|---|---|
Revenues: | |||||||
Licensing revenue | |||||||
- | - | - | - | 21,611 | 18,394 | 8,063 | 3,182 |
Collaborative development revenue | |||||||
- | - | - | - | 2,415 | 13,229 | 20,865 | 2,228 |
Total revenues | |||||||
- | - | - | - | 24,026 | 31,623 | 28,928 | 5,410 |
Total revenues | |||||||
5,281 | 2,607 | 42,000 | - | - | - | - | - |
Cost of revenue | |||||||
600 | 466 | 8,400 | - | - | - | - | - |
Gross profit | |||||||
4,681 | 2,141 | 33,600 | - | 24,026 | - | - | - |
Operating expenses: | |||||||
Research and development | |||||||
71,677 | 69,373 | 75,484 | 94,161 | 39,885 | 25,900 | 28,093 | 10,184 |
General and administrative | |||||||
24,267 | 23,715 | 23,231 | 18,734 | 13,530 | 7,287 | 3,700 | 4,031 |
Total operating expenses | |||||||
95,944 | 93,088 | 98,715 | 112,895 | 53,415 | 33,187 | 31,793 | 14,215 |
Loss from operations | |||||||
-91,263 | -90,947 | -65,115 | -112,895 | -29,389 | -1,564 | -2,865 | -8,805 |
Interest expense | |||||||
5,726 | 3,534 | - | - | - | - | - | - |
Other income, net | |||||||
2,352 | 3,187 | 1,955 | 508 | -261 | 10 | - | - |
Change in fair value of preferred stock warrant liability | |||||||
- | - | - | - | - | 1,593 | 3,506 | 950 |
Other income (expense), net | |||||||
- | - | - | - | - | - | -52 | -30 |
Loss before provision for income taxes | |||||||
-94,637 | -91,294 | -63,160 | -112,387 | -29,650 | -3,147 | -6,423 | -9,785 |
Provision for income taxes | |||||||
303 | 4 | 1,179 | - | -29 | 67 | 141 | - |
Net loss | |||||||
-94,940 | -91,298 | -64,339 | -112,387 | -29,621 | -3,214 | - | -9,785 |
Net loss per common share, basic and diluted | |||||||
-1.47 | -1.62 | -1.36 | -2.80 | -1.29 | -0.31 | -5.82 | -11.32 |
Shares used in computing net loss per share - basic and diluted | |||||||
64,478 | 56,219 | 47,435 | 40,118 | 22,892 | 10,248 | 1,127 | 864 |
Comprehensive loss: | |||||||
Net loss | |||||||
-94,940 | -91,298 | -64,339 | -112,387 | -29,621 | - | - | - |
Unrealized (losses) gains on available-for-sale securities | |||||||
58 | 9 | 24 | -71 | - | - | - | - |
Comprehensive loss | |||||||
-94,882 | -91,289 | -64,315 | -112,458 | -29,621 | - | - | - |
Net (loss) income and comprehensive (loss) income | |||||||
- | - | - | - | - | - | -6,564 | - |
Licensing | |||||||
Total revenue | |||||||
4,500 | 2,320 | 42,000 | - | - | - | - | - |
Collaborative development | |||||||
Total revenues | |||||||
459 | - | - | - | - | - | - | - |
Other | |||||||
Total revenues | |||||||
322 | 287 | - | - | - | - | - | - |