| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|---|
Operating activities: | |||||||||
Net and comprehensive loss | |||||||||
-23,270 | -10,396 | -21,400 | -16,983 | -17,070 | -30 | -28 | -27 | -27 | -22 |
Adjustments to reconcile net and comprehensive loss to net cash used in operating activities: | |||||||||
Depreciation | |||||||||
76 | 46 | 51 | 69 | 57 | - | - | - | - | - |
Stock-based compensation | |||||||||
1,085 | 3,431 | 649 | 488 | 469 | - | - | - | - | - |
Loss on disposal of assets | |||||||||
-94 | - | - | - | - | - | - | - | - | - |
Consulting expenses related to warrants | |||||||||
53 | - | - | - | - | - | - | - | - | - |
Amortization of debt issuance costs | |||||||||
- | - | 75 | 188 | - | - | - | - | - | - |
Interest expense related to convertible note conversion | |||||||||
- | - | 204 | 2 | - | - | - | - | - | - |
Changes in operating assets and liabilities: | |||||||||
Prepaid research and development contracts | |||||||||
-443 | 441 | -40 | - | - | - | - | - | - | - |
Other current assets | |||||||||
119 | 293 | 109 | - | - | - | - | - | - | - |
Deposits | |||||||||
-0 | 20 | - | - | - | - | - | - | - | - |
Accounts payable and accrued expenses | |||||||||
-2,217 | 1,864 | 1,604 | - | -1,071 | - | - | - | - | - |
Accounts receivable | |||||||||
- | - | - | -114 | 60 | - | - | - | - | - |
Prepaid expenses and current other assets | |||||||||
- | - | - | -90 | 210 | - | - | - | - | - |
Accounts payable and other current liabilities | |||||||||
- | - | - | 311 | - | - | - | - | - | - |
Net cash provided by financing activities | |||||||||
- | - | - | 12,296 | - | - | - | - | - | - |
Decrease in prepaid expenses | |||||||||
- | - | - | - | - | -2 | 1 | -1 | 0 | 0 |
Increase in accounts payable | |||||||||
- | - | - | - | - | 2 | -1 | -1 | 0 | 1 |
Increase in accrued interest | |||||||||
- | - | - | - | - | 6 | 5 | 4 | 3 | 1 |
Increase in accrued expenses | |||||||||
- | - | - | - | - | 3 | 0 | 0 | 0 | - |
Increase (decrease) in accrued expenses | |||||||||
- | - | - | - | - | - | - | - | - | 0 |
Net cash used in operating activities | |||||||||
-23,852 | -5,808 | -18,883 | - | -17,884 | -16 | -23 | -24 | -22 | -19 |
Net cash used in operating activities | |||||||||
- | - | - | -15,718 | - | - | - | - | - | - |
Investing activities: | |||||||||
Purchase of furniture and equipment | |||||||||
236 | 37 | 8 | 113 | 41 | - | - | - | - | - |
Proceeds from maturities of short-term investments | |||||||||
- | - | 50 | - | - | - | - | - | - | - |
Net cash used in investing activities | |||||||||
-236 | -37 | 41 | - | -41 | - | - | - | - | - |
Financing activities: | |||||||||
Net cash used in investing activities | |||||||||
- | - | - | -113 | - | - | - | - | - | - |
Proceeds from exercise of stock options | |||||||||
- | 76 | 36 | 18 | 3 | - | - | - | - | - |
Proceeds from issuances of convertible notes | |||||||||
- | - | 297 | 12,542 | - | - | - | - | - | - |
Cash paid for debt issuance costs | |||||||||
- | - | - | 264 | - | - | - | - | - | - |
Payments on notes payable, stockholders | |||||||||
- | - | - | - | - | - | 0 | 0 | - | - |
Payments on notes payable, stockholders | |||||||||
- | - | - | - | - | - | - | - | 0 | 0 |
Proceeds from sale of common stock | |||||||||
- | 51,621 | 40,247 | - | - | - | 0 | 0 | 0 | 0 |
Cash paid in connection with the sale of common stock | |||||||||
- | 3,502 | 3,084 | - | - | - | - | - | - | - |
Proceeds from notes payable, stockholders | |||||||||
- | - | - | - | - | 15 | 25 | 25 | 0 | 35 |
Net cash provided by financing activities | |||||||||
- | 48,195 | 37,496 | - | 3 | 15 | 25 | 25 | 0 | 35 |
Net decrease in cash and cash equivalents | |||||||||
-24,089 | 42,349 | - | - | - | - | - | - | - | - |
Net (decrease) increase in cash and cash equivalents | |||||||||
- | - | 18,654 | -3,534 | -17,922 | -1 | 1 | 0 | -22 | 15 |
Conversion of redeemable convertible preferred stock into common stock | |||||||||
- | - | 74,701 | - | - | - | - | - | - | - |
Conversion of convertible notes and accrued interest into common stock | |||||||||
- | - | 13,447 | - | - | - | - | - | - | - |
Accretion of redeemable convertible preferred stock to redemption value | |||||||||
- | - | 943 | 4,152 | 348 | - | - | - | - | - |
Extinguishment of redeemable convertible preferred stock | |||||||||
- | - | - | 224 | - | - | - | - | - | - |