| Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | |||||||||
Net income/loss | |||||||||
-15,482 | -29,203 | -22,718 | -13,774 | -23,391 | -24,600 | -10,872 | -10,762 | -30,129 | -36,136 |
Adjustments to reconcile net loss to net cash used in operating activities: | |||||||||
Depreciation and amortization | |||||||||
46 | 65 | 101 | 161 | 603 | 864 | 1,064 | 1,172 | 1,425 | 1,695 |
Amortization of premium on marketable securities | |||||||||
-691 | 28 | -48 | -464 | -1,120 | -2,144 | -1,873 | -1,117 | -1,130 | -917 |
Amortization of deferred gain on sale leaseback | |||||||||
- | - | - | 232 | 552 | 552 | 552 | 552 | 552 | -552 |
Amortization of debt discount | |||||||||
322 | 330 | - | - | - | - | - | - | - | - |
Change in fair value of warrant liability | |||||||||
1,552 | 902 | - | - | - | - | - | - | - | - |
Non-cash stock compensation | |||||||||
1,503 | 1,434 | 1,865 | 2,261 | 3,282 | 3,943 | 4,135 | 3,830 | 3,259 | 3,431 |
Gain on auction rate securities | |||||||||
- | - | - | - | 254 | 57 | 113 | 20 | 4,362 | 3,204 |
Gain on sale of property and equipment | |||||||||
- | - | - | 277 | 388 | - | 0 | - | - | - |
Impairment of property and equipment | |||||||||
- | - | - | - | 280 | - | - | - | - | - |
Changes in operating assets and liabilities: | |||||||||
Contract receivables | |||||||||
5,984 | - | - | - | - | - | - | - | - | - |
Loss on auction rate securities put option | |||||||||
- | - | - | - | - | - | - | - | -5,074 | -1,610 |
Prepaid expenses and others, net | |||||||||
314 | -322 | 108 | -1,029 | 30 | 363 | -3,867 | 2,901 | -1,357 | 1,704 |
Other long-term assets | |||||||||
- | - | - | - | - | - | - | 68 | 53 | -383 |
Accounts payable and accrued expenses | |||||||||
4,690 | -497 | 2,466 | -713 | -1,523 | -1,693 | -1,769 | -4,904 | 4,476 | -1,900 |
Deferred revenue | |||||||||
- | 1,500 | -4,591 | -11,079 | -10,929 | -13,366 | -31,837 | -10,650 | -16,441 | -6,220 |
Restructuring accrual, net of current portion | |||||||||
- | - | - | - | - | - | - | - | - | -78 |
Net cash used in operating activities | |||||||||
-12,976 | -25,175 | -22,937 | -22,160 | -31,782 | -33,680 | -34,204 | -23,738 | -34,816 | -41,758 |
Cash flows from investing activities: | |||||||||
Purchases of marketable securities | |||||||||
112,580 | 41,971 | 30,975 | 36,978 | 33,366 | 40,581 | 121,498 | 185,969 | 91,484 | 94,086 |
Proceeds from sale or maturity of marketable securities | |||||||||
59,295 | 30,033 | 39,856 | 60,479 | 63,189 | 75,224 | 101,122 | 149,717 | 154,128 | 32,097 |
Proceeds from sale of property and equipment | |||||||||
- | - | - | 298 | 500 | - | 0 | - | - | - |
Purchases of property and equipment | |||||||||
- | - | 15 | 315 | - | - | 117 | 594 | 357 | 660 |
Net cash used in investing activities | |||||||||
-53,285 | -11,938 | 8,866 | 23,484 | 30,323 | 34,643 | -20,493 | -36,846 | 62,287 | -62,649 |
Proceeds from notes payable and warrants | |||||||||
- | 15,000 | - | - | - | - | - | - | - | - |
Debt issuance costs associated with notes payable and warrants | |||||||||
49 | 376 | - | - | - | - | - | - | - | - |
Proceeds from stock offering, net of offering costs | |||||||||
64,561 | 17,951 | 15,174 | - | - | - | 56,256 | 46,756 | - | - |
Proceeds from convertible preferred stock offering and warrants, net | |||||||||
- | 9,483 | - | - | - | - | - | - | - | - |
Payments for notes payable amendment costs | |||||||||
- | - | - | - | 1,700 | - | 0 | - | 44,400 | 1,650 |
Proceeds from stock option exercises and employee stock plan purchases | |||||||||
756 | 17 | 181 | 134 | 105 | 289 | 1,673 | 4,466 | 835 | 718 |
Net cash (used in) provided by financing activities | |||||||||
- | - | - | 134 | -1,595 | 289 | 57,929 | 51,222 | -43,565 | -932 |
Net cash provided by financing activities | |||||||||
65,268 | 42,075 | 15,355 | - | - | - | - | - | - | - |
Net increase (decrease) in cash and cash equivalents | |||||||||
-993 | 4,962 | 1,284 | 1,458 | -3,054 | 1,252 | 3,232 | -9,362 | -16,094 | -105,339 |
Interest paid on debt | |||||||||
- | - | - | 0 | 35 | 32 | 26 | 25 | - | - |
Interest on debt | |||||||||
1,344 | 1,190 | 0 | - | - | - | - | - | 274 | 655 |
Income taxes | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - | 550 |
Taxes refunded | |||||||||
- | - | - | - | - | - | - | - | 550 | - |