| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues | ||||||||||
Revenues | ||||||||||
Revenues | ||||||||||
5,633 | 24,291 | 3,708 | 17,347 | - | - | - | - | - | - | - |
Contract revenue from Healios | ||||||||||
- | - | - | - | 10,298 | 286 | 755 | - | - | - | - |
Contract revenue | ||||||||||
- | - | - | - | - | - | - | 7,380 | 9,015 | 6,685 | 1,079 |
Grant revenue | ||||||||||
- | - | - | - | 1,650 | 1,337 | 1,683 | 1,328 | 1,329 | 2,254 | 1,080 |
Total revenues | ||||||||||
- | - | - | - | 11,948 | 1,623 | 2,438 | 8,708 | 10,344 | 8,939 | 2,159 |
Costs and expenses | ||||||||||
Research and development | ||||||||||
39,045 | 38,656 | 27,841 | 24,838 | 21,316 | 23,366 | 20,484 | 19,636 | 18,930 | 14,779 | 11,920 |
General and administrative | ||||||||||
11,378 | 10,442 | 8,466 | 7,835 | 7,536 | 6,909 | 6,065 | 4,753 | 4,916 | 5,387 | 5,621 |
Depreciation | ||||||||||
698 | 855 | 684 | 382 | 267 | 360 | 346 | 320 | 278 | 284 | 233 |
Total costs and expenses | ||||||||||
51,121 | 49,953 | 36,991 | 33,055 | 29,119 | 30,635 | - | - | - | - | - |
Gain on Business Interruption Insurance Recovery | ||||||||||
0 | 617 | 0 | 700 | - | - | - | - | - | - | - |
Total costs and expenses | ||||||||||
- | - | - | - | - | - | 26,895 | 24,709 | 24,124 | 20,450 | 17,774 |
Loss from operations | ||||||||||
-45,488 | -25,045 | -33,283 | -15,026 | -17,171 | -29,012 | -24,457 | -16,001 | -13,780 | -11,511 | -15,615 |
Income from change in fair value of warrants, net | ||||||||||
0 | 0 | -728 | 557 | -772 | -6,591 | 6,324 | -2,404 | - | - | - |
Other income, net | ||||||||||
906 | 762 | 314 | 209 | -61 | 86 | 38 | -1,138 | -778 | -69 | -126 |
Loss before income taxes | ||||||||||
- | - | - | -15,374 | -16,460 | -22,335 | -30,743 | -14,735 | - | - | - |
Income tax benefit | ||||||||||
- | - | - | -37 | -38 | -253 | - | - | - | - | - |
Proportional share of comprehensive loss of equity method investment | ||||||||||
- | - | - | - | - | - | - | -28 | 28 | - | - |
Unrealized loss on available-for-sale securities | ||||||||||
- | - | - | - | - | - | - | - | -26 | -45 | - |
Other comprehensive (loss) income items | ||||||||||
- | - | - | - | - | - | - | - | 2 | -45 | - |
Net loss and comprehensive loss | ||||||||||
-44,582 | -24,283 | -32,241 | -15,337 | -16,422 | -22,082 | -30,743 | -14,763 | -13,744 | -11,422 | - |
Net loss per share, basic and diluted (in dollars per share) | ||||||||||
-0.29 | -0.18 | -0.29 | -0.18 | - | - | - | - | -0.59 | -0.60 | -0.81 |
(Expense) income from change in fair value of warrants | ||||||||||
- | - | - | - | - | - | - | - | 812 | - | - |
Interest income | ||||||||||
- | - | - | - | - | - | - | - | - | 203 | 375 |
Net loss | ||||||||||
- | - | - | - | - | - | - | -14,735 | -13,746 | -11,377 | -15,366 |
Net (loss) income per share, basic (in dollars per share) | ||||||||||
- | - | - | - | -0.20 | -0.29 | -0.53 | -0.45 | - | - | - |
Weighted average shares outstanding, basic (in shares) | ||||||||||
- | - | - | - | 82,143 | 76,954 | 57,674 | 32,556 | - | - | - |
Net (loss) income per share, diluted (in dollars per share) | ||||||||||
- | - | - | - | -0.20 | -0.31 | -0.53 | -0.45 | - | - | - |
Weighted average shares outstanding, diluted (in shares) | ||||||||||
- | - | - | - | 82,851 | 78,541 | 57,674 | 32,556 | - | - | - |
Weighted average shares outstanding, basic and diluted (in shares) | ||||||||||
151,696 | 136,641 | 112,053 | 84,715 | - | - | - | - | 23,239 | 18,929 | 18,928 |
Royalty and other contract revenue | ||||||||||
Revenues | ||||||||||
0 | 1,461 | 1,925 | 0 | - | - | - | - | - | - | - |
Grant revenue | ||||||||||
Revenues | ||||||||||
116 | 554 | 865 | 1,109 | - | - | - | - | - | - | - |