| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||||
Total revenues | ||||||||||
59,215 | 103,269 | 173,245 | 150,246 | - | - | - | - | - | - | - |
Product sales | ||||||||||
- | - | - | - | 172,288 | 12,193 | 1,153 | 560 | 13,395 | 8,180 | 11,871 |
License revenue | ||||||||||
- | - | - | - | 721 | 2,782 | 3,026 | 6,724 | 10,566 | 19,704 | 20,815 |
Other revenues | ||||||||||
- | - | - | - | - | - | - | 250 | 8,639 | 9,210 | 9,432 |
Total revenues | ||||||||||
- | - | - | - | 173,009 | 14,975 | 4,179 | 7,534 | 32,600 | 37,094 | 42,118 |
Operating expenses: | ||||||||||
Cost of products | ||||||||||
12,125 | 17,516 | 16,301 | 13,248 | 11,410 | 3,383 | 562 | 400 | 6,284 | 6,914 | -10,118 |
Research and development expenses | ||||||||||
32,917 | 39,329 | 33,418 | 34,611 | 25,608 | 17,298 | 15,966 | 14,558 | 25,089 | 28,687 | -30,416 |
Selling, general and administrative expenses | ||||||||||
30,183 | 100,359 | 58,860 | 44,179 | 21,712 | 15,698 | 13,216 | 14,153 | 10,810 | 11,333 | -13,337 |
Fair value remeasurement of acquisition liabilities, with related parties | ||||||||||
- | - | - | - | - | - | - | -18,834 | - | - | - |
Remeasurement of acquisition liabilities | ||||||||||
- | - | - | - | - | - | - | - | 0 | 0 | - |
Impairment of assets | ||||||||||
- | - | - | - | - | - | - | 7,170 | 0 | 0 | - |
Intangible asset amortization | ||||||||||
816 | 6,619 | 3,659 | 13,888 | 12,564 | 11,749 | 0 | 0 | - | - | - |
Business Combination, Acquisition Related Costs | ||||||||||
845 | -22,731 | -31,040 | 49,285 | 30,957 | 57,491 | 28,135 | - | - | - | - |
Impairment of intangible asset | ||||||||||
0 | 66,087 | 0 | 0 | - | - | - | - | - | - | - |
Restructuring costs | ||||||||||
6,441 | 1,016 | 2,542 | 0 | 0 | - | - | - | - | - | - |
Loss on early repayment of related party acquisition-related note | ||||||||||
- | - | - | - | - | 3,013 | 0 | 0 | - | - | - |
Total operating expenses | ||||||||||
83,327 | 208,195 | 83,740 | 155,211 | 102,251 | 108,632 | 57,879 | 17,447 | 42,183 | 46,934 | -53,871 |
Operating loss | ||||||||||
-24,112 | -104,926 | 89,505 | -4,965 | 70,758 | -93,657 | -53,700 | -9,913 | -9,583 | -9,840 | -11,753 |
Investment and other income, net | ||||||||||
1,069 | 452 | 2,136 | 2,758 | 1,236 | 927 | 254 | - | - | - | - |
Interest expense | ||||||||||
- | - | - | - | - | - | - | 118 | 73 | 24 | 100 |
Interest income net | ||||||||||
- | - | - | - | - | - | - | - | - | - | 525 |
Interest expense | ||||||||||
12,483 | 10,622 | 1,052 | 963 | 0 | 5,747 | 2,602 | 0 | 0 | - | - |
Loss on deconsolidation of subsidiary | ||||||||||
-2,678 | 0 | 0 | - | - | - | - | - | - | - | - |
Other expense - changes in fair value of contingent consideration payable | ||||||||||
-378 | 1,899 | 2,071 | -6,548 | -4,883 | - | 573 | - | - | - | - |
Other expense - changes in fair value of related party payable | ||||||||||
- | - | - | - | - | 3,525 | 1,990 | - | - | - | - |
Interest income | ||||||||||
- | - | - | - | - | - | - | 640 | 667 | 464 | - |
Foreign exchange (loss) gain | ||||||||||
- | - | - | - | 10,594 | 11,871 | -288 | -180 | 273 | 109 | -83 |
Other Income | ||||||||||
- | - | - | - | - | - | - | 102 | 134 | 525 | -28 |
Loss before income taxes | ||||||||||
-38,582 | -113,197 | 92,660 | -9,718 | 77,705 | -90,131 | -57,753 | -9,469 | -8,582 | -8,766 | -11,439 |
Income tax benefit | ||||||||||
-5,356 | -17,893 | 24,389 | 31,558 | 35,907 | -644 | -11,244 | -4,729 | 192 | 209 | - |
Net income (loss) from continuing operations | ||||||||||
- | - | - | - | - | -89,487 | -46,509 | -4,740 | - | - | - |
Net income from discontinued operations | ||||||||||
- | - | - | - | - | 4,018 | 3,584 | 1,512 | - | - | - |
Net Income (Loss) Attributable to Parent | ||||||||||
-33,226 | -95,304 | 68,271 | -41,276 | 41,798 | -85,469 | -42,925 | -3,228 | -8,774 | -8,975 | -11,439 |
Earnings Per Share [Abstract] | ||||||||||
Continuing operations (in usd per share) | ||||||||||
- | - | - | - | - | -2.47 | -1.83 | -0.19 | - | - | - |
Discontinued operations (in usd per share) | ||||||||||
- | - | - | - | - | 0.11 | 0.14 | 0.06 | - | - | - |
Net income (loss) per share - basic (in dollars per share) | ||||||||||
-0.89 | -2.55 | 1.69 | -1.00 | 1.03 | -2.36 | -1.69 | -0.13 | -0.36 | -0.37 | -0.47 |
Continuing operations (in usd per share) | ||||||||||
- | - | - | - | - | -2.47 | -1.83 | -0.19 | - | - | - |
Discontinued operations (in usd per share) | ||||||||||
- | - | - | - | - | 0.11 | 0.14 | - | - | - | - |
Discontinued operations | ||||||||||
- | - | - | - | - | - | - | 0.06 | - | - | - |
Net income (loss) per share - diluted (in dollars per share) | ||||||||||
-0.89 | -2.55 | 1.63 | -1.00 | 0.96 | -2.36 | -1.69 | -0.13 | -0.36 | -0.37 | -0.47 |
Weighted average number of shares outstanding | ||||||||||
Weighted average number of shares outstanding - basic (in shares) | ||||||||||
37,403 | 37,325 | 40,465 | 41,248 | 40,580 | 36,214 | 25,450 | 25,135 | 24,669 | 24,411 | 24,225 |
Weighted average number of shares outstanding - diluted (in shares) | ||||||||||
37,403 | 37,325 | 41,765 | 41,248 | 43,619 | 36,214 | 25,450 | 25,135 | 24,669 | 24,411 | 24,225 |
Product sales | ||||||||||
Total revenues | ||||||||||
59,215 | 101,423 | 172,841 | 147,222 | - | - | - | - | - | - | - |
License revenue | ||||||||||
Total revenues | ||||||||||
0 | 1,846 | 404 | 3,024 | - | - | - | - | - | - | - |