| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating expenses: | ||||||||||||||||||||
Research and development | ||||||||||||||||||||
73,565 | 53,647 | 41,593 | 31,798 | 26,345 | 23,495 | 20,837 | 19,268 | 18,724 | 19,957 | 21,270 | 22,368 | 22,658 | 21,199 | 17,601 | 13,556 | 9,886 | 6,776 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||||||
15,749 | 13,598 | 10,674 | 9,765 | 9,759 | 9,351 | 9,002 | 8,626 | 7,930 | 7,206 | 7,075 | 6,888 | 6,673 | 6,343 | 5,471 | 4,331 | 3,259 | 2,419 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||||||
89,315 | 67,245 | 52,267 | 41,563 | 36,104 | 32,846 | 29,840 | 27,894 | 26,655 | 27,164 | 28,345 | 29,256 | 29,332 | 27,543 | 23,072 | 17,888 | 13,146 | 9,196 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||||
-89,315 | -67,245 | -52,267 | -41,563 | -36,104 | -32,846 | -29,840 | -27,894 | -26,655 | -27,164 | -28,345 | -29,256 | -29,332 | -27,543 | -23,072 | -17,888 | -13,146 | -9,196 | 0 | 0 | 0 |
Interest and amortization of debt discount (expense) | ||||||||||||||||||||
-1,013 | -1,239 | -1,109 | -1,052 | -1,030 | -1,127 | -1,218 | -1,291 | -1,332 | -1,340 | -1,177 | -821 | -472 | -132 | -71 | -364 | -590 | -736 | 0 | 0 | 0 |
Tax credit | ||||||||||||||||||||
- | - | 0 | - | - | - | 0 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - |
Change in fair value of warrant liabilities | ||||||||||||||||||||
- | - | - | - | - | -2,791 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | 108 | 0 | 0 | 0 |
Change in fair value of embedded derivative liabilities | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 274 | 0 | 0 | 0 |
Loss on extinguishment of debt | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - |
Net loss | ||||||||||||||||||||
-90,188 | -68,345 | -53,135 | -42,281 | -36,800 | -30,965 | -28,798 | -26,950 | -25,753 | -28,943 | -28,841 | -29,602 | -29,330 | -27,201 | -23,237 | -20,619 | -15,936 | -12,210 | 0 | 0 | 0 |
Net loss per common share, basic and diluted | ||||||||||||||||||||
-0.88 | -0.72 | -0.56 | -0.41 | -0.32 | -0.33 | -0.31 | -0.32 | -0.19 | -0.29 | -0.27 | -0.30 | -0.41 | -0.37 | -0.38 | -0.36 | -0.31 | -0.23 | -0.41 | -0.19 | -0.19 |
Weighted average common shares outstanding, basic and diluted | ||||||||||||||||||||
37,061 | 34,781 | 34,445 | 33,801 | 33,052 | 29,916 | 26,325 | 25,791 | 25,501 | 24,290 | 23,634 | 23,595 | 19,537 | 19,154 | 19,149 | 19,149 | 19,149 | 14,456 | 11,108 | 11,108 | 11,108 |