| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Operating expenses: | ||||||
Research and development | ||||||
11,032 | 20,259 | 17,854 | 16,650 | 33,365 | 45,978 | 52,985 |
General and administrative | ||||||
6,441 | 7,621 | 6,745 | 7,107 | 14,870 | 13,775 | 9,013 |
Total operating expenses | ||||||
17,473 | 27,880 | 24,599 | 23,757 | 48,235 | 59,753 | 61,998 |
Other operating income | ||||||
- | - | - | - | 1,667 | 0 | 0 |
Loss from operations | ||||||
-17,473 | -27,880 | -24,599 | -23,757 | -46,568 | -59,753 | -61,998 |
Change in fair value of common stock warrant liability | ||||||
-2,682 | -24,877 | 30,403 | 590 | 0 | 0 | - |
Warrant amendment charge | ||||||
674 | 0 | 0 | - | - | - | - |
Interest and other income, net | ||||||
397 | 378 | 184 | 95 | 109 | 79 | 0 |
Pre-tax loss | ||||||
-15,068 | -2,625 | -54,818 | -24,252 | -46,459 | -59,674 | -61,998 |
Income tax benefit | ||||||
-1,801 | -5,439 | 0 | -438 | 0 | 0 | 0 |
Net loss | ||||||
- | - | - | - | - | -59,674 | -61,998 |
Net loss | ||||||
-13,267 | 2,814 | -54,818 | -23,814 | -46,459 | - | - |
Weighted average shares outstanding: | ||||||
Basic (in shares) | ||||||
4,503 | 3,829 | 2,596 | 15,057 | - | - | - |
Diluted (in shares) | ||||||
4,503 | 4,336 | 2,596 | 15,057 | - | - | - |
Basic and diluted (in shares) | ||||||
- | - | - | - | 12,267 | 7,898 | - |
Net loss per share: | ||||||
Basic (in usd per share) | ||||||
-2.95 | 0.73 | -21.11 | -1.58 | - | - | - |
Diluted (in usd per share) | ||||||
-2.95 | -5.07 | -21.11 | -1.58 | - | - | - |
Basic and diluted (in dollars per share) | ||||||
- | - | - | - | -3.79 | -7.56 | - |