| Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Sep'15 | Jun'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating expenses: | ||||||||||||||||
Research and development | ||||||||||||||||
142,985 | 135,267 | 124,316 | 104,370 | 97,828 | 88,778 | 81,206 | 75,902 | 70,830 | 62,493 | 55,451 | 48,770 | 37,466 | 28,895 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||
41,345 | 38,973 | 35,476 | 30,002 | 25,827 | 22,352 | 20,136 | 17,275 | 15,298 | 13,898 | 12,302 | 11,276 | 9,747 | 8,377 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||
184,330 | 174,240 | 159,792 | 134,372 | 123,655 | 111,130 | 101,342 | 93,177 | 86,128 | 76,391 | 67,753 | 60,046 | 47,213 | 37,272 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||
-184,330 | -174,240 | -159,792 | -134,372 | -123,655 | -111,130 | -101,342 | -93,177 | -86,128 | -76,391 | -67,753 | -60,046 | -47,213 | -37,272 | 0 | 0 | 0 |
Interest income, net | ||||||||||||||||
9,305 | 8,702 | 7,643 | 6,030 | 3,946 | 2,658 | 1,479 | 767 | 650 | 545 | 522 | 472 | 359 | 306 | 0 | 0 | 0 |
Other expense, net | ||||||||||||||||
-463 | -500 | -492 | -479 | -141 | -96 | -77 | -74 | -61 | -53 | -88 | -94 | -169 | -101 | 0 | 0 | 0 |
Net Income (Loss) Attributable to Parent | ||||||||||||||||
-175,488 | -166,038 | -152,641 | -128,821 | -117,604 | -106,322 | -97,694 | -90,238 | -85,539 | -75,899 | -67,319 | -59,668 | -47,023 | -37,067 | 0 | 0 | 0 |
Unrealized (losses) gains on investments, net | ||||||||||||||||
0 | 0 | 0 | - | 0 | 0 | 0 | - | 0 | 0 | - | - | 0 | 0 | 0 | 0 | 0 |
Comprehensive loss | ||||||||||||||||
-175,295 | -165,849 | -152,560 | -128,881 | -117,634 | -106,328 | -97,759 | -90,289 | -85,555 | -75,939 | -67,352 | -59,687 | -46,999 | -37,052 | 0 | 0 | 0 |
Net loss per share, basic and diluted (USD per share) | ||||||||||||||||
-1.00 | -1.01 | -1.13 | -0.84 | -0.97 | -0.85 | -0.74 | -0.82 | -0.88 | -0.87 | -0.83 | 6.63 | -0.94 | -6.43 | -4.85 | -5.48 | -8.46 |
Weighted-average number of shares used in computing net loss per share, basic and diluted (in shares) | ||||||||||||||||
45,543 | 44,426 | 43,625 | 42,481 | 37,359 | 36,935 | 34,582 | 29,956 | 28,388 | 26,212 | 21,755 | 21,910 | 16,423 | 2,200 | 2,159 | 1,283 | 640 |