| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||
Net loss | ||||||
-347,694 | -236,642 | -148,119 | -72,495 | -52,769 | -40,285 | -20,912 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Depreciation and amortization | ||||||
5,259 | 4,246 | 1,578 | 1,582 | 948 | 622 | 501 |
Noncash lease expense | ||||||
4,991 | - | - | - | - | - | - |
Noncash interest expense | ||||||
- | - | - | - | 109 | 85 | 26 |
Change in fair value of warrant liability | ||||||
- | - | - | - | 445 | 100 | -4 |
Stock-based compensation | ||||||
54,653 | 30,534 | 12,523 | 6,140 | 5,180 | 2,326 | 351 |
Accretion of premiums and discounts on investments | ||||||
-4,949 | -4,381 | -320 | 301 | - | - | - |
Other | ||||||
- | -6 | 32 | 73 | - | - | - |
Changes in assets and liabilities: | ||||||
Accounts receivable | ||||||
599 | -349 | 413 | - | - | - | - |
Unbilled accounts receivable | ||||||
22,597 | 151 | -3,577 | - | 3,414 | - | - |
Prepaid expenses and other current assets | ||||||
3,338 | -6,086 | 6,853 | -1,307 | 1,482 | 469 | -16 |
Other assets | ||||||
-20 | 4,242 | 458 | 304 | 552 | - | -20 |
Accounts payable | ||||||
1,448 | -445 | 1,532 | 4 | 1,391 | -512 | 541 |
Accrued expenses | ||||||
36,980 | 24,804 | 14,597 | 5,773 | 1,956 | 2,873 | 550 |
Deferred revenue | ||||||
-94 | 5,479 | -11,861 | 33,594 | 13,641 | - | - |
Deferred rent | ||||||
- | -640 | 14,320 | -488 | 2,871 | -140 | -114 |
Operating lease liabilities | ||||||
-2,095 | - | - | - | - | - | - |
Net cash used in operating activities | ||||||
-278,015 | -175,009 | -119,865 | -24,513 | -31,676 | -35,400 | -19,025 |
Purchases of property and equipment | ||||||
14,013 | 12,677 | 15,512 | 2,354 | 4,883 | 700 | 257 |
Restricted cash | ||||||
- | - | - | - | 1,196 | - | - |
Purchases of investments | ||||||
738,387 | 801,236 | 360,835 | 264,467 | - | - | - |
Maturities of investments | ||||||
735,934 | 652,825 | 304,000 | 48,000 | - | - | - |
Net cash provided by investing activities | ||||||
-16,466 | -161,088 | -72,347 | -218,821 | -6,079 | -700 | -257 |
Proceeds from term loan | ||||||
- | - | - | - | - | 7,000 | 3,000 |
Principal payments on loan payable | ||||||
- | 1,528 | 2,583 | 3,333 | 1,806 | 750 | - |
Payment of offering costs | ||||||
284 | 281 | 965 | 143 | 2,046 | - | - |
Proceeds from public offerings of common stock, net of commissions, underwriting discounts and offering costs | ||||||
327,750 | - | 542,225 | 135,125 | 156,815 | - | - |
Debt issuance costs | ||||||
- | - | - | - | - | 18 | 48 |
Proceeds from issuance of common stock | ||||||
13,288 | 6,425 | 5,271 | 928 | 259 | 268 | 53 |
Other financing activities | ||||||
-116 | -162 | - | - | - | - | - |
Net cash provided by financing activities | ||||||
340,638 | 4,454 | 543,948 | 132,577 | 153,222 | 81,353 | 17,992 |
Net increase in cash, cash equivalents, and restricted cash | ||||||
46,157 | -331,643 | 351,736 | -110,757 | 115,467 | 45,253 | -1,290 |
Effect of exchange rate changes on cash, cash equivalents and restricted cash | ||||||
18 | - | - | - | - | - | - |
Supplemental cash flow information | ||||||
Public offering costs incurred but unpaid at period end | ||||||
- | - | 317 | 433 | - | - | - |
Property and equipment purchases unpaid at period end | ||||||
958 | 912 | 3,947 | - | 1,244 | - | - |
Conversion of convertible preferred stock into common stock | ||||||
- | - | - | - | 114,808 | - | - |
Reclassification of warrant liability to additional paid-in-capital | ||||||
- | - | - | - | 810 | - | - |
Cash paid for interest | ||||||
5 | 267 | 151 | 316 | 452 | 215 | 53 |
Cash paid for taxes, net | ||||||
185 | 123 | 37 | - | - | - | - |
Issuance of warrants in connection with term loan | ||||||
- | - | - | - | - | 145 | 119 |