| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||||||||||||||
Net loss | ||||||||||||||||||||
-110,955 | -66,331 | -94,275 | -99,681 | -87,407 | -80,322 | -72,723 | -27,048 | -56,549 | -49,027 | -37,703 | -33,412 | -27,977 | -21,263 | -16,834 | -18,894 | -15,504 | -15,575 | -12,642 | -12,980 | -11,572 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||||||||||
Depreciation and amortization | ||||||||||||||||||||
1,571 | -2,075 | 2,605 | 3,551 | 1,178 | 1,170 | 1,163 | 1,133 | 780 | 391 | 396 | 393 | 398 | 393 | 407 | 396 | 386 | 333 | 204 | 202 | 209 |
Noncash lease expense | ||||||||||||||||||||
1,391 | - | - | - | 1,041 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Noncash interest expense | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | 8 | 11 | - | 17 | 20 | 22 | 25 | 26 | 29 | 29 |
Change in fair value of warrant liability | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 407 | 38 |
Stock-based compensation | ||||||||||||||||||||
16,859 | 15,699 | 14,993 | 13,666 | 10,295 | 8,832 | 8,391 | 7,762 | 5,549 | 3,705 | 3,599 | 2,979 | 2,240 | 1,646 | 1,905 | 1,487 | 1,102 | 1,195 | 971 | 2,174 | 840 |
Accretion of premiums and discounts on investments | ||||||||||||||||||||
-134 | -583 | -1,393 | -1,641 | -1,332 | -1,447 | -1,259 | -983 | -692 | -286 | -110 | -10 | 86 | 97 | 94 | 75 | 35 | - | - | - | - |
Other | ||||||||||||||||||||
- | - | - | - | - | -16 | 2 | 4 | 4 | - | - | - | - | - | - | - | - | - | - | - | - |
Changes in assets and liabilities: | ||||||||||||||||||||
Accounts receivable | ||||||||||||||||||||
3,847 | -1,751 | 1,664 | 363 | 323 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Unbilled accounts receivable | ||||||||||||||||||||
-2,152 | 20,180 | -1,946 | 4,144 | 219 | - | - | - | - | -3,435 | 360 | 249 | -751 | - | 104 | -881 | 818 | 944 | 547 | 1,439 | 484 |
Inventory | ||||||||||||||||||||
382 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Prepaid expenses and other current assets | ||||||||||||||||||||
1,408 | -3,837 | 2,335 | 3,459 | 1,381 | -79 | -3,332 | 798 | -3,473 | 6,681 | -2,436 | 636 | 1,972 | -597 | 1,233 | 319 | -2,262 | 438 | 405 | 275 | 364 |
Other assets | ||||||||||||||||||||
66 | -78 | -121 | 65 | 114 | -23 | 681 | 3,557 | 27 | -342 | 804 | 10 | -14 | 299 | -12 | 28 | -11 | - | - | - | - |
Accounts payable | ||||||||||||||||||||
3,715 | 2,543 | -4,386 | 2,309 | 982 | -689 | 1,029 | -303 | -482 | 1,657 | -422 | 226 | 71 | 377 | -800 | -140 | 567 | 707 | -97 | -736 | 1,517 |
Accrued expenses | ||||||||||||||||||||
-16,576 | 10,572 | 16,414 | 11,202 | -1,208 | 5,878 | 7,331 | 12,120 | -525 | 5,521 | 5,123 | 5,505 | -1,552 | 3,846 | -275 | 2,523 | -321 | 412 | 1,088 | 571 | -115 |
Deferred revenue | ||||||||||||||||||||
-575 | 4,742 | -3,139 | -966 | -731 | -1,033 | -1,095 | 8,561 | -954 | -1,398 | -4,633 | -2,815 | -3,015 | -4,113 | -1,705 | -3,715 | 43,127 | -1,220 | -957 | 986 | 14,832 |
Deferred rent | ||||||||||||||||||||
- | - | - | - | - | -186 | -151 | -163 | -140 | 7,999 | 5,952 | 504 | -135 | -133 | -118 | -119 | -118 | 2,456 | 418 | 37 | -40 |
Operating lease liabilities | ||||||||||||||||||||
-1,073 | 61 | -591 | -596 | -969 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash used in operating activities | ||||||||||||||||||||
-109,328 | -44,895 | -71,704 | -81,228 | -80,188 | -67,582 | -55,005 | -2,859 | -49,563 | -34,750 | -26,518 | -27,517 | -31,080 | -18,797 | -18,634 | -17,833 | 30,751 | -13,046 | -12,465 | -11,055 | 4,890 |
Purchases of property and equipment | ||||||||||||||||||||
1,525 | 3,891 | 6,182 | 2,170 | 1,770 | 425 | 2,618 | 3,322 | 6,312 | 10,580 | 4,475 | 247 | 210 | 18 | 522 | 552 | 1,262 | 3,754 | 822 | 288 | 19 |
Restricted cash | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | -119 | -70 | 0 | 0 | 1,266 |
Purchases of investments | ||||||||||||||||||||
139,250 | 140,873 | 132,225 | 352,373 | 112,916 | 152,334 | 159,617 | 150,469 | 338,816 | 45,547 | 105,396 | 191,889 | 18,003 | 159,149 | 36,096 | 0 | 69,222 | - | - | - | - |
Maturities of investments | ||||||||||||||||||||
200,635 | 212,500 | 212,944 | 106,490 | 204,000 | 209,000 | 178,825 | 139,000 | 126,000 | 106,000 | 102,000 | 42,000 | 54,000 | - | - | - | - | - | - | - | - |
Net cash provided by investing activities | ||||||||||||||||||||
59,860 | 67,736 | 74,537 | -248,053 | 89,314 | 56,241 | 16,590 | -14,791 | -219,128 | 49,873 | -7,871 | -150,136 | 35,787 | -138,286 | -15,618 | 5,448 | -70,365 | -3,684 | -822 | -288 | -1,285 |
Principal payments on loan payable | ||||||||||||||||||||
- | - | - | - | - | 278 | 417 | 416 | 417 | 583 | 583 | 584 | 833 | 833 | 833 | 834 | 833 | 556 | 417 | 416 | 417 |
Payment of offering costs | ||||||||||||||||||||
- | - | - | - | - | 0 | 0 | 117 | 164 | 42 | 207 | 227 | 489 | - | - | - | - | 0 | 81 | 1,819 | 146 |
Proceeds from public offerings of common stock, net of commissions, underwriting discounts and offering costs | ||||||||||||||||||||
308,541 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from issuance of Series C convertible preferred stock, net of issuance costs | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -3 |
Proceeds from issuance of common stock | ||||||||||||||||||||
1,609 | - | - | - | 2,039 | - | - | - | 3,643 | 2,453 | 1,162 | 754 | 902 | 481 | 102 | 316 | 29 | 213 | -22 | 49 | 19 |
Other financing activities | ||||||||||||||||||||
- | 0 | -44 | -44 | -28 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash provided by financing activities | ||||||||||||||||||||
310,150 | 1,834 | 4,495 | 332,298 | 2,011 | 764 | 113 | 515 | 3,062 | 327,853 | 372 | 216,143 | -420 | 134,630 | -731 | -518 | -804 | -343 | -520 | 154,632 | -547 |
Net increase in cash, cash equivalents, and restricted cash | ||||||||||||||||||||
260,682 | 24,675 | 7,328 | 3,017 | 11,137 | -10,577 | -38,302 | -17,135 | -265,629 | 342,976 | -34,017 | 38,490 | 4,287 | -22,453 | -34,983 | -12,903 | -40,418 | -17,073 | -13,807 | 143,289 | 3,058 |
Effect of exchange rate changes on cash, cash equivalents and restricted cash | ||||||||||||||||||||
50 | 28 | -13 | 19 | -16 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Supplemental cash flow information | ||||||||||||||||||||
Public offering costs incurred but unpaid at period end | ||||||||||||||||||||
118 | - | - | - | - | - | - | - | 166 | 217 | -206 | -210 | 516 | - | - | - | - | - | - | -777 | 805 |
Property and equipment purchases unpaid at period end | ||||||||||||||||||||
465 | -2,267 | -103 | 1,850 | 1,478 | 784 | -1,986 | -1,012 | 3,126 | 751 | 1,276 | 1,840 | 80 | - | -101 | -128 | 244 | - | - | - | - |
Cash paid for interest | ||||||||||||||||||||
- | - | - | - | - | 206 | 30 | 13 | 18 | 26 | 34 | 41 | 50 | 62 | 74 | 85 | 95 | 105 | 111 | 116 | 120 |
Cash paid for taxes, net | ||||||||||||||||||||
32 | 55 | 33 | 44 | 53 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |