| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||||||||||||||
Net loss | ||||||||||||||||||||
-371,242 | -347,694 | -361,685 | -340,133 | -267,500 | -236,642 | -205,347 | -170,327 | -176,691 | -148,119 | -120,355 | -99,486 | -84,968 | -72,495 | -66,807 | -62,615 | -56,701 | -52,769 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||||||||||
Depreciation and amortization | ||||||||||||||||||||
5,652 | 5,259 | 8,504 | 7,062 | 4,644 | 4,246 | 3,467 | 2,700 | 1,960 | 1,578 | 1,580 | 1,591 | 1,594 | 1,582 | 1,522 | 1,319 | 1,125 | 948 | 0 | 0 | 0 |
Noncash lease expense | ||||||||||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Noncash interest expense | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | 0 | 62 | - | 84 | 93 | 102 | 109 | 0 | 0 | 0 |
Change in fair value of warrant liability | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 445 | 0 | 0 | 0 |
Stock-based compensation | ||||||||||||||||||||
61,217 | 54,653 | 47,786 | 41,184 | 35,280 | 30,534 | 25,407 | 20,615 | 15,832 | 12,523 | 10,464 | 8,770 | 7,278 | 6,140 | 5,689 | 4,755 | 5,442 | 5,180 | 0 | 0 | 0 |
Accretion of premiums and discounts on investments | ||||||||||||||||||||
-3,751 | -4,949 | -5,813 | -5,679 | -5,021 | -4,381 | -3,220 | -2,071 | -1,098 | -320 | 63 | 267 | 352 | 301 | 0 | 0 | 0 | - | - | - | - |
Other | ||||||||||||||||||||
- | - | - | - | - | -6 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Changes in assets and liabilities: | ||||||||||||||||||||
Accounts receivable | ||||||||||||||||||||
4,123 | 599 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Unbilled accounts receivable | ||||||||||||||||||||
20,226 | 22,597 | 0 | 0 | 0 | - | - | - | - | -3,577 | 0 | 0 | -1,406 | - | 985 | 1,428 | 3,748 | 3,414 | 0 | 0 | 0 |
Inventory | ||||||||||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Prepaid expenses and other current assets | ||||||||||||||||||||
3,365 | 3,338 | 7,096 | 1,429 | -1,232 | -6,086 | 674 | 1,570 | 1,408 | 6,853 | -425 | 3,244 | 2,927 | -1,307 | -272 | -1,100 | -1,144 | 1,482 | 0 | 0 | 0 |
Other assets | ||||||||||||||||||||
-68 | -20 | 35 | 837 | 4,329 | 4,242 | 3,923 | 4,046 | 499 | 458 | 1,099 | 283 | 301 | 304 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||||||||||||||
4,181 | 1,448 | -1,784 | 3,631 | 1,019 | -445 | 1,901 | 450 | 979 | 1,532 | 252 | -126 | -492 | 4 | 334 | 1,037 | 441 | 1,391 | 0 | 0 | 0 |
Accrued expenses | ||||||||||||||||||||
21,612 | 36,980 | 32,286 | 23,203 | 24,121 | 24,804 | 24,447 | 22,239 | 15,624 | 14,597 | 12,922 | 7,524 | 4,542 | 5,773 | 2,339 | 3,702 | 1,750 | 1,956 | 0 | 0 | 0 |
Deferred revenue | ||||||||||||||||||||
62 | -94 | -5,869 | -3,825 | 5,702 | 5,479 | 5,114 | 1,576 | -9,800 | -11,861 | -14,576 | -11,648 | -12,548 | 33,594 | 36,487 | 37,235 | 41,936 | 13,641 | 0 | 0 | 0 |
Deferred rent | ||||||||||||||||||||
- | - | - | - | - | -640 | 7,545 | 13,648 | 14,315 | 14,320 | 6,188 | 118 | -505 | -488 | 2,101 | 2,637 | 2,793 | 2,871 | 0 | 0 | 0 |
Operating lease liabilities | ||||||||||||||||||||
-2,199 | -2,095 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash used in operating activities | ||||||||||||||||||||
-307,155 | -278,015 | -300,702 | -284,003 | -205,634 | -175,009 | -142,177 | -113,690 | -138,348 | -119,865 | -103,912 | -96,028 | -86,344 | -24,513 | -18,762 | -12,593 | -5,815 | -31,676 | 0 | 0 | 0 |
Purchases of property and equipment | ||||||||||||||||||||
13,768 | 14,013 | 10,547 | 6,983 | 8,135 | 12,677 | 22,832 | 24,689 | 21,614 | 15,512 | 4,950 | 997 | 1,302 | 2,354 | 6,090 | 6,390 | 6,126 | 4,883 | 0 | 0 | 0 |
Restricted cash | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | -189 | -189 | -189 | 1,196 | 0 | 0 | 0 |
Purchases of investments | ||||||||||||||||||||
764,721 | 738,387 | 749,848 | 777,240 | 575,336 | 801,236 | 694,449 | 640,228 | 681,648 | 360,835 | 474,437 | 405,137 | 213,248 | 264,467 | 0 | 0 | 0 | - | - | - | - |
Maturities of investments | ||||||||||||||||||||
732,569 | 735,934 | 732,434 | 698,315 | 730,825 | 652,825 | 549,825 | 473,000 | 376,000 | 304,000 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
Net cash provided by investing activities | ||||||||||||||||||||
-45,920 | -16,466 | -27,961 | -85,908 | 147,354 | -161,088 | -167,456 | -191,917 | -327,262 | -72,347 | -260,506 | -268,253 | -112,669 | -218,821 | -84,219 | -69,423 | -75,159 | -6,079 | 0 | 0 | 0 |
Principal payments on loan payable | ||||||||||||||||||||
- | - | - | - | - | 1,528 | 1,833 | 1,999 | 2,167 | 2,583 | 2,833 | 3,083 | 3,333 | 3,333 | 3,056 | 2,640 | 2,222 | 1,806 | 0 | 0 | 0 |
Payment of offering costs | ||||||||||||||||||||
- | - | - | - | - | 281 | 323 | 530 | 640 | 965 | 0 | 0 | 0 | - | - | - | - | 2,046 | 0 | 0 | 0 |
Proceeds from public offerings of common stock, net of commissions, underwriting discounts and offering costs | ||||||||||||||||||||
0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from issuance of Series C convertible preferred stock, net of issuance costs | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 |
Proceeds from issuance of common stock | ||||||||||||||||||||
0 | - | - | - | 0 | - | - | - | 8,012 | 5,271 | 3,299 | 2,239 | 1,801 | 928 | 660 | 536 | 269 | 259 | 0 | 0 | 0 |
Other financing activities | ||||||||||||||||||||
- | -116 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash provided by financing activities | ||||||||||||||||||||
648,777 | 340,638 | 339,568 | 335,186 | 3,403 | 4,454 | 331,543 | 331,802 | 547,430 | 543,948 | 350,725 | 349,622 | 132,961 | 132,577 | -2,396 | -2,185 | 152,965 | 153,222 | 0 | 0 | 0 |
Net increase in cash, cash equivalents, and restricted cash | ||||||||||||||||||||
295,702 | 46,157 | 10,905 | -34,725 | -54,877 | -331,643 | 21,910 | 26,195 | 81,820 | 351,736 | -13,693 | -14,659 | -66,052 | -110,757 | -105,377 | -84,201 | 71,991 | 115,467 | 0 | 0 | 0 |
Effect of exchange rate changes on cash, cash equivalents and restricted cash | ||||||||||||||||||||
84 | 18 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Supplemental cash flow information | ||||||||||||||||||||
Public offering costs incurred but unpaid at period end | ||||||||||||||||||||
0 | - | - | - | - | - | - | - | -33 | 317 | 0 | 0 | 0 | - | - | - | - | - | - | 0 | 0 |
Property and equipment purchases unpaid at period end | ||||||||||||||||||||
-55 | 958 | 4,009 | 2,126 | -736 | 912 | 879 | 4,141 | 6,993 | 3,947 | 0 | 0 | 0 | - | 0 | 0 | 0 | - | - | - | - |
Cash paid for interest | ||||||||||||||||||||
- | - | - | - | - | 267 | 87 | 91 | 119 | 151 | 187 | 227 | 271 | 316 | 359 | 396 | 427 | 452 | 0 | 0 | 0 |
Cash paid for taxes, net | ||||||||||||||||||||
164 | 185 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |