| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Revenues: | ||||||
Total revenues | ||||||
66,512 | 44,521 | 21,426 | 27,772 | 11,400 | - | - |
Cost and operating expenses | ||||||
Research and development | ||||||
331,450 | 243,621 | 144,687 | 81,131 | 48,588 | 31,844 | 15,928 |
Selling, general and administrative | ||||||
96,388 | 47,928 | 27,986 | 19,218 | 14,456 | 7,890 | 5,072 |
Total cost and operating expenses | ||||||
427,838 | 291,549 | 172,673 | 100,349 | 63,044 | 39,734 | 21,000 |
Other income (expense): | ||||||
Interest income (expense), net | ||||||
13,732 | 10,566 | 3,204 | 469 | 696 | 453 | 138 |
Other income (expense), net | ||||||
-100 | -180 | -76 | 551 | -429 | -98 | 226 |
Total other income | ||||||
13,632 | 10,386 | 3,128 | 82 | -1,125 | -551 | 88 |
Net loss | ||||||
-347,694 | -236,642 | -148,119 | -72,495 | -52,769 | -40,285 | -20,912 |
Other comprehensive loss: | ||||||
Unrealized gain (losses) on pension benefit obligations | ||||||
-2,985 | - | - | - | - | - | - |
Unrealized gain (losses) on available-for-sale investments | ||||||
671 | 105 | -251 | -18 | - | - | - |
Currency translation adjustments | ||||||
-40 | -16 | - | - | - | - | - |
Comprehensive loss | ||||||
-350,048 | -236,553 | -148,370 | -72,513 | -52,769 | -40,285 | - |
Net loss per share - basic and diluted | ||||||
-7.27 | -5.39 | -3.92 | -2.64 | - | - | - |
Reconciliation of net loss applicable to common stockholders: | ||||||
Net loss | ||||||
-347,694 | -236,642 | -148,119 | -72,495 | -52,769 | -40,285 | -20,912 |
Convertible preferred stock dividends | ||||||
- | - | - | - | 3,153 | 5,765 | 2,870 |
Net loss applicable to common stockholders | ||||||
- | - | - | - | -55,922 | -46,050 | -23,782 |
Net loss per share applicable to common stockholders - basic and diluted (in dollars per share) | ||||||
- | - | - | - | -3.07 | -32.41 | -23.43 |
Weighted-average number of common shares used in net loss per share - basic and diluted | ||||||
47,829 | 43,867 | 37,793 | 27,492 | 18,236 | 1,421 | 1,015 |