| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Sep'13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue: | |||||||||||||||||||||||||
Total revenue | |||||||||||||||||||||||||
- | - | - | - | - | 0 | 0 | 17,065 | 5,189 | - | 7,254 | 7,255 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Collaboration revenue | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 4,192 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Total revenue | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 4,192 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Operating expenses: | |||||||||||||||||||||||||
Research and development | |||||||||||||||||||||||||
20,125 | 17,902 | 17,221 | 20,928 | 20,239 | 16,977 | 16,420 | 17,305 | 15,493 | 15,496 | 10,833 | 10,142 | 6,640 | 6,593 | 6,313 | 7,776 | 7,066 | 5,833 | 6,752 | 5,533 | 5,630 | 4,972 | 3,894 | 4,183 | 3,318 | 2,735 |
General and administrative | |||||||||||||||||||||||||
4,946 | 4,551 | 3,906 | 3,984 | 4,164 | 3,247 | 3,087 | 3,498 | 3,508 | 3,300 | 3,074 | 2,848 | 3,308 | 3,011 | 2,319 | 2,665 | 2,591 | 2,295 | 2,198 | 2,341 | 2,237 | 1,866 | 1,347 | 1,309 | 832 | 583 |
Total operating expenses | |||||||||||||||||||||||||
25,071 | 22,453 | 21,127 | 24,912 | 24,403 | 20,224 | 19,507 | 20,803 | 19,001 | 18,796 | 13,907 | 12,990 | 9,948 | 9,604 | 8,632 | 10,441 | 9,657 | 8,128 | 8,950 | 7,874 | 7,867 | 6,838 | 5,241 | 5,492 | 4,150 | 3,318 |
Loss from operations | |||||||||||||||||||||||||
-25,071 | -22,453 | -21,127 | -24,912 | -24,403 | -20,224 | -19,507 | -3,738 | -13,812 | -11,542 | -6,653 | -5,735 | -5,756 | -9,604 | -8,632 | -10,441 | -9,657 | -8,128 | -8,950 | -7,874 | -7,867 | -6,838 | -5,241 | -5,492 | -4,150 | -3,318 |
Interest and other income, net | |||||||||||||||||||||||||
625 | 725 | 834 | 760 | 716 | - | 658 | 663 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Interest income, net | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | 606 | - | 582 | 541 | 169 | 84 | 88 | 83 | 75 | 60 | 50 | 56 | 9 | - | - | - | - | - |
Other income, net | |||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 2 | 1 | 1 | - |
Net loss | |||||||||||||||||||||||||
-24,446 | -21,728 | -20,293 | -24,152 | -23,687 | -19,499 | -18,849 | -3,075 | -13,206 | -10,974 | -6,071 | -5,194 | -5,587 | -9,520 | -8,544 | -10,358 | -9,582 | -8,068 | -8,900 | -7,818 | -7,858 | -6,833 | -5,239 | -5,491 | -4,149 | -3,318 |
Net loss per share, basic and diluted | |||||||||||||||||||||||||
-0.38 | -0.33 | -0.38 | -0.58 | -0.61 | -0.51 | -0.52 | -0.09 | -0.37 | -0.30 | -0.17 | -0.15 | -0.22 | -0.44 | -0.44 | -0.55 | -0.52 | -0.44 | -0.49 | -0.44 | -0.44 | 59.20 | -16.85 | -24.22 | -22.80 | -34.22 |
Weighted average common shares used to compute net loss per share, basic and diluted | |||||||||||||||||||||||||
64,556 | 55,304 | 53,775 | 41,303 | 38,866 | 38,358 | 36,405 | 35,874 | 35,779 | 35,702 | 35,475 | 35,348 | 25,279 | 21,061 | 19,507 | 18,987 | 18,389 | 18,166 | 18,105 | 17,963 | 17,946 | 17,888 | 311 | 227 | 182 | 97 |