| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Revenue | ||||||
- | - | 500 | - | - | - | - |
Operating expenses: | ||||||
Research and development | ||||||
18,317 | 17,042 | 18,682 | 25,450 | 23,030 | 15,686 | 13,994 |
General and administrative | ||||||
8,771 | 9,329 | 8,912 | 10,108 | 8,629 | 5,995 | 4,125 |
Total operating expenses | ||||||
27,088 | 26,371 | 27,594 | 35,558 | 31,659 | 21,681 | 18,119 |
Loss from operations | ||||||
-27,088 | -26,371 | -27,094 | -35,558 | -31,659 | -21,681 | -18,119 |
Other income (expense): | ||||||
Interest expense | ||||||
- | 100 | - | - | - | - | - |
Interest expense | ||||||
- | - | 462 | 837 | 978 | 206 | - |
Interest and investment income | ||||||
845 | 425 | 160 | 242 | - | - | - |
Other (expense) income, net | ||||||
-50 | 176 | 32 | 93 | 7 | 3 | 1 |
Total other income, net | ||||||
795 | 501 | -270 | -502 | -971 | -203 | 1 |
Net loss | ||||||
-26,293 | -25,870 | -27,364 | -36,060 | -32,630 | -21,884 | -18,118 |
Net loss per share - basic and diluted (in dollars per share) | ||||||
-2.35 | -5.12 | -12.62 | -2.22 | -4.06 | -51.56 | -47.80 |
Weighted-average common shares outstanding used in net loss per share - basic and diluted (in shares) | ||||||
11,199 | 5,054 | 2,168 | 16,230 | 8,041 | 424 | 379 |