| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Sep'14 | Jun'14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue | ||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Operating expenses: | ||||||||||||||||||||||
Research and development | ||||||||||||||||||||||
19,409 | 18,317 | 17,713 | 16,913 | 15,992 | 17,042 | 17,372 | 18,251 | 18,531 | 18,682 | 20,953 | 22,113 | 24,412 | 25,450 | 25,860 | 25,737 | 24,850 | 23,030 | 20,903 | 18,812 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||||||||
9,387 | 8,771 | 8,716 | 8,842 | 9,074 | 9,329 | 8,623 | 8,938 | 8,941 | 8,912 | 9,602 | 9,523 | 9,701 | 10,108 | 10,359 | 10,400 | 9,655 | 8,629 | 7,392 | 6,646 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||||||||
28,796 | 27,088 | 26,429 | 25,755 | 25,066 | 26,371 | 25,995 | 27,189 | 27,472 | 27,594 | 30,555 | 31,636 | 34,113 | 35,558 | 36,219 | 36,137 | 34,505 | 31,659 | 28,295 | 25,458 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||||||
-28,796 | -27,088 | -26,429 | -25,755 | -25,066 | -26,371 | -25,745 | -26,689 | -26,972 | -27,094 | -30,305 | -31,636 | -34,113 | -35,558 | -36,219 | -36,137 | -34,505 | -31,659 | -28,295 | -25,458 | 0 | 0 | 0 |
Other income (expense): | ||||||||||||||||||||||
Interest expense | ||||||||||||||||||||||
- | - | - | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Interest expense | ||||||||||||||||||||||
- | - | - | - | - | - | - | 276 | 370 | 462 | 556 | 650 | 743 | 837 | 930 | 1,013 | 1,072 | 978 | 767 | 0 | 0 | 0 | - |
Interest and investment income | ||||||||||||||||||||||
786 | 845 | 870 | 833 | 619 | 425 | 284 | 152 | 153 | 160 | 187 | 192 | 228 | 242 | 0 | 0 | 0 | - | - | - | - | - | - |
Other (expense) income, net | ||||||||||||||||||||||
-197 | -50 | -184 | 24 | 234 | 176 | 335 | 168 | 49 | 32 | 29 | 47 | 110 | 93 | 78 | 63 | -24 | 7 | 13 | 16 | 0 | 0 | 0 |
Total other income, net | ||||||||||||||||||||||
589 | 795 | 686 | 847 | 810 | 501 | 438 | 44 | -168 | -270 | -340 | -411 | -405 | -502 | -669 | -817 | -1,043 | -971 | -754 | -469 | 0 | 0 | 0 |
Net loss | ||||||||||||||||||||||
-28,207 | -26,293 | -25,743 | -24,908 | -24,256 | -25,870 | -25,307 | -26,645 | -27,140 | -27,364 | -30,645 | -32,047 | -34,518 | -36,060 | -36,888 | -36,954 | -35,548 | -32,630 | -29,049 | -25,927 | 0 | 0 | 0 |
Net loss per share - basic and diluted (in dollars per share) | ||||||||||||||||||||||
-0.50 | -0.55 | -0.56 | -0.62 | -0.62 | 0.54 | -0.80 | -1.98 | -2.88 | -11.58 | -0.31 | -0.32 | -0.41 | -0.46 | -0.54 | -0.61 | -0.61 | 17.70 | -0.55 | -8.07 | -13.14 | -13.55 | -13.42 |
Weighted-average common shares outstanding used in net loss per share - basic and diluted (in shares) | ||||||||||||||||||||||
15,898 | 11,980 | 11,624 | 11,505 | 9,686 | 7,186 | 7,103 | 3,272 | 2,655 | -54,780 | 22,563 | 21,796 | 19,093 | 18,698 | 15,512 | 15,373 | 15,335 | 15,378 | 15,297 | 996 | 494 | 444 | 399 |