| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|---|
Operating activities | |||||||||
Net loss | |||||||||
-55,489 | -37,966 | 17,859 | -39,963 | -47,305 | -46,929 | -38,673 | -39,891 | -4,617 | -3,096 |
Adjustments to reconcile net loss to net cash used in operating activities: | |||||||||
Stock-based compensation | |||||||||
11,638 | 10,833 | 8,748 | 8,535 | 8,985 | 8,214 | 6,242 | 4,953 | 2,642 | 2,346 |
Depreciation of property and equipment | |||||||||
550 | 512 | 418 | 348 | 477 | 543 | 576 | 592 | 754 | 660 |
Amortization of right-of-use assets | |||||||||
1,092 | 0 | 0 | - | - | - | - | - | - | - |
Non-cash interest income, net | |||||||||
1,499 | 1,071 | -143 | -179 | -1,007 | -2,157 | -2,065 | -2,571 | -2,021 | 939 |
Changes in assets and liabilities: | |||||||||
Accounts receivable, other | |||||||||
176 | 0 | 0 | - | - | - | - | - | - | - |
Accounts receivable | |||||||||
-2,058 | -49,032 | 20,885 | 30,205 | - | -393 | -763 | 649 | -11,945 | -22,989 |
Prepaids and other current assets | |||||||||
-719 | 668 | 727 | -35 | -236 | 376 | -34 | -692 | 764 | -395 |
Other assets | |||||||||
-61 | 31 | 80 | 119 | - | 21 | - | -1,935 | 1,935 | -17 |
Accounts payable | |||||||||
188 | -434 | 729 | -4 | -73 | -161 | 159 | 214 | -405 | -103 |
Other liabilities | |||||||||
4,459 | 4,158 | 80 | 3,773 | -2,654 | 1,865 | -723 | 1,758 | -2,593 | 779 |
Deferred revenue from related party | |||||||||
-33,724 | -7,929 | -1,407 | 96,566 | - | - | -3,761 | -4,402 | -3,628 | -6,289 |
Net cash used in operating activities | |||||||||
-70,123 | 16,436 | 4,878 | 39,145 | -39,327 | -34,315 | -33,318 | -32,227 | 3,420 | 18,637 |
Investing activities | |||||||||
Purchases of property and equipment, net | |||||||||
790 | 838 | 723 | 304 | 218 | 352 | 554 | 472 | 166 | 1,193 |
Purchases of investments | |||||||||
211,973 | 192,480 | 133,845 | 136,234 | 24,372 | 100,837 | 136,600 | 177,566 | 113,251 | 90,258 |
Sales of investments | |||||||||
4,967 | 0 | 0 | - | 4,051 | - | 5,142 | 5,582 | 17,260 | - |
Maturities of investments | |||||||||
195,270 | 140,250 | 150,170 | 87,774 | 54,423 | 139,528 | 100,344 | 115,552 | 109,352 | 62,849 |
Net cash provided by (used in) investing activities | |||||||||
-12,526 | -53,068 | 15,602 | -48,764 | 33,884 | 38,339 | -31,668 | -56,904 | 13,195 | -28,602 |
Financing activities | |||||||||
Proceeds from issuance of common stock | |||||||||
73,276 | 0 | 0 | 7,000 | - | - | 64,365 | 57,017 | - | - |
Proceeds from exercise of stock options | |||||||||
22,857 | 10,467 | 3,269 | 1,820 | 2,191 | 2,123 | 2,678 | 966 | 260 | 117 |
Employees' tax withheld and paid for restricted stock units | |||||||||
1,313 | 678 | 429 | - | - | - | - | - | - | - |
Borrowings under credit facility agreement, net of issuance costs | |||||||||
0 | 14,911 | 4,676 | - | - | - | - | - | - | - |
Proceeds from exercise of warrants | |||||||||
- | - | - | - | - | - | 312 | - | 1,058 | - |
Proceeds from the issuance of convertible note | |||||||||
- | - | - | - | - | - | - | - | 10,000 | - |
Proceeds from equipment financing obligations | |||||||||
- | - | - | - | - | - | - | - | 700 | 1,500 |
Payments on equipment financing obligations | |||||||||
- | - | - | - | - | 330 | 571 | 547 | 534 | 672 |
Net cash provided by financing activities | |||||||||
94,820 | 24,700 | 7,516 | 8,820 | 2,191 | 1,793 | 66,784 | 57,436 | 11,484 | 945 |
Net increase in cash, cash equivalents and restricted cash | |||||||||
12,171 | -11,932 | 27,996 | -799 | -3,252 | 5,817 | 1,798 | -31,695 | 28,099 | -9,020 |
Supplemental disclosures of cash flow information | |||||||||
Cash paid for interest | |||||||||
1,735 | 748 | 0 | - | - | 137 | 26 | 50 | 87 | 130 |
Right-of-use assets obtained in exchange for lease obligations | |||||||||
2,796 | 0 | 0 | - | - | - | - | - | - | - |
Purchases of property and equipment, net recorded in accounts payable | |||||||||
378 | 0 | 0 | - | - | - | - | - | - | - |
Cash refund for income taxes | |||||||||
- | - | - | - | - | - | - | - | 16 | 247 |
Issuance of common stock for settlement of convertible debt, including accrued interest | |||||||||
- | - | - | - | - | - | - | 10,215 | - | - |