| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenue from Collaborative Arrangement, Excluding Revenue from Contract with Customer | ||||||||||||||||||||||||
2,530 | - | 19,100 | - | 0 | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Operating expenses: | ||||||||||||||||||||||||
Research and development | ||||||||||||||||||||||||
12,996 | 11,490 | 11,499 | 10,743 | 12,669 | 13,046 | 11,278 | 11,619 | 13,199 | 10,230 | 9,159 | 13,191 | 10,243 | 11,310 | 8,729 | 8,471 | 7,189 | 7,564 | 6,766 | 4,210 | 4,935 | 3,474 | 1,992 | 966 | 278 |
Cost of in-process research and development acquired | ||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1,607 | - |
General and administrative | ||||||||||||||||||||||||
4,095 | 4,405 | 4,573 | 3,525 | 3,735 | 3,552 | 3,447 | 3,533 | 3,611 | 3,229 | 3,090 | 3,424 | 3,155 | 3,043 | 3,607 | 3,391 | 2,696 | 2,364 | 2,441 | 2,236 | 1,797 | 1,175 | 1,328 | 522 | 281 |
Total operating expenses | ||||||||||||||||||||||||
17,091 | 15,895 | 16,072 | 14,268 | 16,404 | 16,598 | 14,725 | 15,152 | 16,810 | 13,459 | 12,249 | 16,615 | 13,398 | 14,353 | 12,336 | 11,862 | 9,885 | 9,928 | 9,207 | 6,446 | 6,732 | 4,649 | 3,320 | 3,095 | 559 |
Loss from operations | ||||||||||||||||||||||||
-14,561 | -14,080 | 3,028 | -14,268 | -16,404 | -16,598 | -14,725 | -15,152 | -16,810 | -13,459 | -12,249 | -16,615 | -13,398 | -14,353 | -12,336 | -11,862 | -9,885 | -9,928 | -9,207 | -6,446 | -6,732 | -4,649 | -3,320 | -3,095 | -559 |
Other income (expense): | ||||||||||||||||||||||||
Gain (Loss) on Derivative Instruments, Net, Pretax | ||||||||||||||||||||||||
0 | -11 | 0 | 681 | -270 | 4,124 | 888 | -1,112 | 0 | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Interest income, net | ||||||||||||||||||||||||
22 | 57 | 11 | 40 | 113 | 182 | 222 | 164 | 61 | 31 | -8 | -30 | 0 | -41 | 109 | 107 | 96 | 60 | 33 | 32 | -5 | 0 | 1 | -44 | -45 |
Other expense | ||||||||||||||||||||||||
- | - | - | 0 | - | - | - | 206 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Change in fair value of convertible notes payable | ||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | -80 | -103 |
Total other income (expense) | ||||||||||||||||||||||||
- | - | 0 | 721 | - | 5,366 | -4 | -1,154 | 61 | 31 | -8 | -30 | 0 | -41 | 109 | 107 | 96 | - | 33 | - | - | - | - | - | - |
Total other income (expense) | ||||||||||||||||||||||||
22 | - | 11 | - | -157 | - | 1,106 | - | - | - | - | - | - | - | - | - | - | - | - | 32 | -5 | - | 1 | -124 | -148 |
Net loss and comprehensive loss | ||||||||||||||||||||||||
-14,539 | -14,023 | 3,039 | -13,547 | -16,561 | -12,342 | -13,619 | -16,306 | -16,749 | -13,428 | -12,257 | -16,645 | -13,398 | -14,394 | -12,227 | -11,755 | -9,789 | -9,868 | -9,174 | -6,414 | -6,737 | -4,649 | -3,319 | -3,219 | -707 |
Allocation of earnings to participating securities | ||||||||||||||||||||||||
- | - | 444 | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Recognition of beneficial conversion feature | ||||||||||||||||||||||||
2,762 | 0 | 0 | 0 | 0 | - | 0 | 10,329 | - | - | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net loss attributable to common shareholders | ||||||||||||||||||||||||
-17,301 | -13,579 | 2,595 | -13,547 | -16,561 | - | -13,619 | -26,635 | - | - | -12,257 | -16,645 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Basic earnings (loss) per common share (in dollars per share) | ||||||||||||||||||||||||
-0.46 | - | 0.08 | - | -0.58 | - | -0.49 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Diluted earnings (loss) per common share (in dollars per share) | ||||||||||||||||||||||||
- | - | 0.08 | - | - | - | -0.49 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Shares used to compute basic net income (loss) per share (in shares) | ||||||||||||||||||||||||
37,856 | - | 33,006 | - | 28,532 | - | 27,705 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Weighted Average Number of Shares Outstanding, Diluted | ||||||||||||||||||||||||
- | - | 38,687 | - | - | - | 27,705 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Basic and diluted net loss per common share (USD per share) | ||||||||||||||||||||||||
- | - | - | -0.49 | - | - | - | -1.13 | -0.80 | -0.66 | -0.73 | -0.99 | -0.80 | -0.88 | -0.88 | -0.85 | -0.71 | 3.93 | -0.67 | -0.59 | -5.92 | -4.68 | -2.98 | -5.04 | -1.81 |
Shares used to compute basic and diluted net loss per common share (in shares) | ||||||||||||||||||||||||
- | - | - | 27,786 | - | - | - | 23,592 | 20,894 | 19,511 | 16,864 | 16,831 | 16,795 | 16,366 | 13,910 | 13,871 | 13,807 | 13,910 | 13,674 | 10,957 | 1,138 | 1,137 | 1,113 | 638 | 389 |
Net Income (Loss) Attributable to Parent | ||||||||||||||||||||||||
-14,539 | -14,023 | 3,039 | -13,547 | -16,561 | -12,342 | -13,619 | -16,306 | -16,749 | - | -12,257 | -16,645 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Unrealized gain on short-term investments | ||||||||||||||||||||||||
- | - | 0 | - | - | - | 2 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Other Comprehensive Income (Loss), Securities, Available-for-Sale, Unrealized Holding Gain (Loss) Arising During Period, after Tax | ||||||||||||||||||||||||
- | - | - | 0 | - | - | - | 15 | -10 | - | -1 | 4 | -3 | 16 | -13 | -2 | 6 | - | -5 | - | - | - | - | - | - |
Comprehensive loss | ||||||||||||||||||||||||
- | - | 3,039 | -13,547 | - | -12,341 | -13,617 | -16,291 | -16,759 | -13,435 | -12,258 | -16,641 | -13,401 | -14,378 | -12,240 | -11,757 | -9,783 | -9,871 | -9,179 | -6,414 | -6,737 | - | -3,319 | - | - |