| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||||
Revenue sharing arrangement | ||||||||||
- | - | - | - | 4,829 | 7,298 | 4,631 | 150 | 450 | - | - |
Government awards | ||||||||||
- | - | - | - | - | - | - | 2,247 | 3,476 | 4,073 | 46 |
Total revenues | ||||||||||
68,458 | 60,594 | 50,024 | 48,837 | 41,804 | 35,307 | 31,922 | 88,298 | 123,865 | 107,104 | 82,908 |
Costs and operating expenses: | ||||||||||
Cost of product revenue | ||||||||||
15,632 | 12,620 | 14,327 | 9,753 | 6,586 | 9,726 | 14,554 | 30,647 | 41,781 | 27,982 | 16,678 |
Research and development | ||||||||||
33,873 | 29,978 | 29,659 | 22,229 | 20,673 | 22,755 | 31,606 | 56,785 | 61,049 | 52,405 | 54,725 |
Selling, general and administrative | ||||||||||
31,502 | 29,291 | 29,008 | 25,419 | 22,315 | 21,937 | 26,908 | 31,379 | 36,942 | 33,841 | 29,871 |
Total costs and operating expenses | ||||||||||
81,007 | 71,889 | 72,994 | 57,401 | 49,574 | 54,418 | 73,068 | 118,811 | 139,772 | 114,228 | 101,274 |
Loss from operations | ||||||||||
-12,549 | -11,295 | -22,970 | -8,564 | -7,770 | -19,111 | -41,146 | -30,513 | -15,907 | -7,124 | -18,366 |
Interest income | ||||||||||
1,287 | 671 | 147 | 60 | 19 | 18 | 60 | 252 | 273 | 166 | 180 |
Other expenses, net | ||||||||||
-656 | -291 | -92 | -94 | 168 | 234 | 304 | 326 | 675 | 1,199 | 2,037 |
Loss before income taxes | ||||||||||
-11,918 | -10,915 | -22,915 | -8,598 | -7,919 | -19,327 | -41,390 | -30,587 | -16,309 | -8,157 | -20,223 |
Provision for income taxes | ||||||||||
17 | -37 | 81 | -40 | -338 | -256 | -87 | 270 | 241 | 384 | 66 |
Net loss | ||||||||||
-11,935 | -10,878 | -22,996 | -8,558 | -7,581 | -19,071 | -41,303 | -30,857 | -16,550 | -8,541 | -20,289 |
Net loss per share, basic and diluted (usd per share) | ||||||||||
-0.21 | -0.21 | -0.50 | -0.21 | -0.19 | -0.50 | -1.08 | -0.84 | -0.46 | -0.35 | -7.74 |
Weighted average common stock shares used in computing net loss per share, basic and diluted (shares) | ||||||||||
56,525 | 52,205 | 46,228 | 40,629 | 39,438 | 38,209 | 38,231 | 36,768 | 35,674 | 24,594 | 2,622 |
Product Sales [Member] | ||||||||||
Total revenues | ||||||||||
29,465 | 25,590 | 26,685 | 15,321 | 11,376 | 13,064 | 20,423 | 35,924 | 49,021 | 32,835 | 18,554 |
Research and Development Revenue [Member] | ||||||||||
Total revenues | ||||||||||
38,993 | 35,004 | 23,339 | 33,516 | 25,599 | 14,945 | 6,868 | 49,977 | 70,918 | 70,196 | 64,308 |