| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||
Net loss | ||||||
-28,478 | -43,365 | -53,580 | -57,588 | -57,246 | -45,722 | -47,889 |
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | ||||||
Depreciation and amortization expense | ||||||
4,237 | 4,122 | 3,669 | 3,153 | 2,619 | 2,080 | 1,882 |
Amortization of debt discount | ||||||
- | - | 0 | 7 | 135 | 24 | 151 |
Stock-based compensation expense | ||||||
2,837 | 3,886 | 6,048 | 5,324 | 3,607 | 2,550 | 2,337 |
Unrealized foreign exchange loss | ||||||
-606 | -1,806 | - | - | - | - | - |
Non-cash lease expense | ||||||
1,146 | - | - | - | - | - | - |
Provision for bad debts on trade receivables | ||||||
106 | -72 | -15 | 188 | 359 | 6 | 14 |
Goodwill impairment | ||||||
0 | 6,731 | 0 | 0 | - | - | - |
Impairment of Long-Lived Assets to be Disposed of | ||||||
69 | 2,433 | 1,113 | 100 | 0 | 0 | - |
Disposal of long-term assets | ||||||
200 | 4 | 0 | -16 | -2 | -44 | 0 |
Loss on extinguishment of debt | ||||||
-1,085 | 0 | - | - | -205 | 0 | 0 |
Non-cash interest expense | ||||||
423 | 125 | 100 | 0 | 0 | - | - |
Amortization/accretion on investments | ||||||
4 | 18 | -202 | -315 | 0 | - | - |
Deferred tax | ||||||
0 | -37 | 37 | 0 | 0 | - | - |
Changes in operating assets and liabilities: | ||||||
Accounts receivable | ||||||
-2,070 | -28 | -1,490 | -4 | 6,107 | 2,929 | 2,089 |
Royalty receivable | ||||||
20 | -55 | 0 | 0 | - | - | - |
Inventories | ||||||
2,539 | 350 | -2,535 | 200 | 3,829 | 1,071 | 1,424 |
Prepaid expenses and other assets | ||||||
1,623 | -529 | -1,770 | 1,550 | 1,045 | 332 | -47 |
Accounts payable, accrued expenses and other liabilities | ||||||
1,615 | -1,045 | -1,406 | 1,437 | 1,969 | 2,075 | 117 |
Contract liability | ||||||
12,000 | 0 | -306 | -305 | - | - | - |
Advance on research and development | ||||||
3,832 | 0 | - | - | - | - | - |
Deferred royalty revenue | ||||||
- | - | - | - | 4,932 | 0 | 0 |
Other long-term liabilities | ||||||
- | - | 487 | -56 | -51 | -264 | 28 |
Net cash used in operating activities | ||||||
-2,838 | -25,176 | - | - | - | - | - |
Net cash used in operating activities | ||||||
- | - | -37,856 | -49,132 | -54,450 | -43,539 | -46,826 |
Cash flows from investing activities: | ||||||
Acquisition of property and equipment | ||||||
2,926 | 4,059 | 5,233 | 7,161 | 4,643 | 2,614 | 4,112 |
Business acquisition, net of cash acquired | ||||||
- | - | 5,780 | 0 | 0 | - | - |
(Increase) decrease in restricted cash | ||||||
- | - | 162 | -300 | -3,837 | -1,108 | 4,345 |
Purchase of investments | ||||||
0 | 27,430 | 30,991 | 65,614 | 0 | 0 | - |
Maturity of investments | ||||||
7,250 | 47,115 | 32,125 | 37,050 | 0 | 0 | - |
Net cash (used in) provided by investing activities | ||||||
4,324 | 15,626 | - | - | - | - | - |
Net cash provided/(used) in investing activities | ||||||
- | - | -10,041 | -35,425 | -806 | -1,506 | -8,457 |
Cash flows from financing activities: | ||||||
Net proceeds from issuance of preferred stock | ||||||
- | - | - | - | - | 21,598 | 73,578 |
Proceeds from exercise of common stock options | ||||||
184 | 112 | 2,108 | 4,087 | 806 | 121 | 521 |
Proceeds from exercise of common stock warrant | ||||||
- | - | - | - | 18 | 0 | 0 |
Proceeds from exercise of preferred stock warrant | ||||||
- | - | - | - | 4,458 | 0 | 0 |
Debt issuance costs | ||||||
737 | 0 | 434 | 0 | 0 | - | - |
Loss on extinguishment of debt | ||||||
919 | 0 | - | - | - | - | - |
Proceeds from issuance of debt | ||||||
20,000 | 0 | 30,000 | 0 | 0 | 10,000 | 0 |
Payments on long-term debt | ||||||
15,000 | 15,000 | 0 | 485 | 10,278 | 2,382 | 4,496 |
Debt prepayment fee | ||||||
0 | 225 | 0 | 0 | 205 | 0 | 0 |
Net proceeds from issuance of common stock | ||||||
4,999 | 22,768 | 1,023 | 0 | 139,766 | 0 | 0 |
Net cash provided by financing activities | ||||||
8,527 | 7,655 | - | - | - | - | - |
Foreign exchange effect on cash and cash equivalents | ||||||
1 | -73 | - | - | - | - | - |
(Decrease) increase in cash, cash equivalents and restricted cash | ||||||
10,014 | -1,968 | - | - | - | - | - |
Net cash provided by financing activities | ||||||
- | - | 32,697 | 3,602 | 134,565 | 29,337 | 69,603 |
Foreign exchange effect on cash and cash equivalents | ||||||
- | - | -3,709 | 1,027 | -24 | -613 | 167 |
Decrease in cash and cash equivalents | ||||||
- | - | -18,909 | -79,928 | 79,285 | -16,321 | 14,487 |
Supplemental information: | ||||||
Cash paid for income taxes | ||||||
- | - | - | - | 187 | 156 | 123 |
Cash paid for interest | ||||||
2,123 | 2,837 | 1,449 | 48 | 1,284 | 162 | 560 |
Noncash investing and financing activities | ||||||
Issuance of common stock for business acquisition | ||||||
- | - | 594 | 0 | 0 | 177 | 1,533 |
Issuance of common stock for equity financing | ||||||
0 | 77 | 0 | 0 | - | - | - |