| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | ||
|---|---|---|---|---|---|---|
Cash Flows from Operating Activities: | ||||||
Net loss | ||||||
-24,714 | -36,367 | -22,677 | -22,461 | -13,892 | ||
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Stock-based compensation expense | ||||||
3,121 | 1,994 | 3,117 | 3,867 | 3,252 | ||
Change in fair value of warrant liabilities | ||||||
- | - | - | 0 | 438 | ||
Issuance of common shares - Founders Agreement | ||||||
738 | 815 | 0 | 14 | 1,269 | ||
Common shares issuable - Founders Agreement | ||||||
2,510 | 1,748 | 2,296 | 3,919 | 3,024 | ||
Issuance of common shares for license expenses | ||||||
- | - | - | 0 | 633 | ||
Amortization of debt discount | ||||||
- | - | - | 324 | 89 | ||
Research and development-licenses acquired, expensed | ||||||
- | - | 400 | 3,160 | 2,525 | ||
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other assets | ||||||
-509 | -485 | 1,786 | -100 | 171 | ||
Other receivables - related party | ||||||
-1,506 | 1,201 | -490 | 756 | 65 | ||
Accounts payable and accrued expenses | ||||||
-5,043 | 6,721 | 2,699 | 1,883 | 1,790 | ||
Net cash used in operating activities | ||||||
-21,373 | -25,805 | -15,461 | -9,950 | -1,108 | ||
Purchase of research and development licenses | ||||||
- | - | 400 | 3,160 | 2,525 | ||
Net cash used in investing activities | ||||||
- | - | -400 | -3,160 | -2,525 | ||
Proceeds from note payable, net of debt discount | ||||||
- | - | - | 0 | 2,554 | ||
Payment of note payable | ||||||
- | - | - | 2,792 | 0 | ||
Proceeds from issuance of common stock, net of offering costs of $2,195 and $0, respectively | ||||||
- | - | - | 570 | 51,496 | ||
Cash received for issuance of founders shares | ||||||
- | - | - | 0 | 1 | ||
Proceeds from issuance of common stock | ||||||
- | - | 0 | - | - | ||
Offering costs for the issuance of common stock | ||||||
- | - | 0 | - | - | ||
Proceeds from issuance of common stock - At-the-market offering | ||||||
8,011 | 7,981 | - | - | - | ||
Issuance of common shares - At-the-market offering | ||||||
- | - | 0 | - | - | ||
Offering costs for the issuance of common shares - At-the-market offering | ||||||
-198 | -234 | 0 | - | - | ||
Proceeds from issuance of common stock Public offering | ||||||
19,560 | 23,012 | - | - | - | ||
Offering costs for the issuance of common shares - Public offering | ||||||
-1,918 | -2,184 | - | - | - | ||
Net cash (used in) provided by financing activities | ||||||
25,455 | 28,575 | 0 | -2,222 | 54,051 | ||
Net decrease in cash and cash equivalents | ||||||
4,082 | 2,770 | - | - | - | ||
Net (decrease) increase in cash and cash equivalents | ||||||
- | - | -15,861 | -15,332 | 50,418 | ||
Supplemental disclosure of noncash investing and financing activities: | ||||||
Cash paid for interest | ||||||
- | - | - | 20 | 56 | ||
Debt discount associated with warrant liabilities | ||||||
- | - | - | 0 | 175 | ||
Issuance of common shares - Founders Agreement | ||||||
1,748 | 2,296 | 3,919 | 3,024 | 0 | ||
Issuance of common shares - Public offering (offering costs incurred but not paid) | ||||||
69 | 0 | - | - | - | ||