| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Operating activities | ||||||
Net loss | ||||||
-30,770 | -82,818 | -58,975 | -25,882 | - | - | |
Net loss | ||||||
- | - | - | - | -17,639 | -10,189 | |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Depreciation | ||||||
211 | 189 | 182 | 65 | 60 | 33 | |
Share-based compensation expense | ||||||
4,612 | 4,785 | 3,364 | 1,314 | 705 | 427 | |
Non-cash interest expense | ||||||
163 | 154 | 211 | 283 | 104 | 82 | |
Accretion of debt discount | ||||||
67 | 112 | 212 | 108 | 60 | 277 | |
Loss on disposal of fixed assets | ||||||
-63 | - | - | - | -15 | - | |
Change in fair value of warrant liability | ||||||
- | - | - | 156 | 52 | 18 | |
Amortization and accretion on available-for-sale investments, net | ||||||
115 | 748 | 31 | 43 | - | - | |
Changes in operating assets and liabilities: | ||||||
Prepaid expenses and other current assets | ||||||
558 | 505 | 833 | 487 | 145 | -54 | |
Other assets and liabilities | ||||||
159 | 55 | -92 | - | - | - | |
Other assets | ||||||
- | - | - | -882 | -1,763 | 1,154 | |
Accounts payable and accrued liabilities | ||||||
-5,582 | -314 | 4,715 | 1,424 | 632 | 1,137 | |
Deferred revenue | ||||||
5,000 | - | -20 | -520 | - | - | |
Deferred revenue | ||||||
- | - | - | - | 500 | 200 | |
Deferred rent | ||||||
- | - | - | -9 | -9 | 9 | |
Net cash used in operating activities | ||||||
-27,068 | -79,200 | -51,083 | -22,709 | - | - | |
Investing activities | ||||||
Maturities of available-for-sale investments | ||||||
32,950 | 76,470 | 68,543 | 5,708 | - | - | |
Purchase of available-for-sale investments | ||||||
- | 80,142 | 48,116 | 54,485 | - | - | |
Net cash used in operating activities | ||||||
- | - | - | - | -13,902 | -9,124 | |
Change in restricted cash | ||||||
- | - | - | 360 | - | - | |
Acquisition of property and equipment | ||||||
25 | 88 | 306 | 3 | 32 | 140 | |
Net cash (used in) provided by investing activities | ||||||
32,925 | -3,760 | 20,121 | -49,140 | - | - | |
Financing activities | ||||||
Proceeds from at-the-market sales agreement, net of issuance costs | ||||||
10,319 | - | - | - | - | - | |
Proceeds from private placement, net of issuance costs | ||||||
3,324 | - | - | - | - | - | |
Proceeds from the sale of fixed assets | ||||||
- | - | - | - | 4 | - | |
Net cash provided by (used in) investing activities | ||||||
- | - | - | - | -28 | -140 | |
Proceeds from follow-on offering, net of issuance costs | ||||||
- | 79,564 | 5,057 | 33,456 | - | - | |
Proceeds from initial public offering, net of issuance costs | ||||||
- | - | - | 51,376 | - | - | |
Proceeds from exercise of stock options | ||||||
7 | 465 | 239 | 31 | 14 | 5 | |
Proceeds from shares issued under employee stock purchase plan | ||||||
45 | 50 | 66 | - | - | - | |
Proceeds from issuance of long-term debt | ||||||
- | 10,000 | - | 7,857 | 5,976 | 3,000 | |
Principal payments made on long-term debt | ||||||
5,000 | 8,300 | - | 6,330 | - | 125 | |
Net cash provided by financing activities | ||||||
8,695 | 81,779 | 5,362 | 86,390 | - | - | |
Net cash provided by financing activities | ||||||
- | - | - | - | 25,944 | 15,624 | |
Net (decrease) increase in cash, cash equivalents and restricted cash | ||||||
14,552 | -1,181 | -25,600 | 14,541 | - | - | |
Supplemental disclosure | ||||||
Interest paid | ||||||
843 | 751 | 653 | 250 | - | - | |
Interest paid | ||||||
- | - | - | - | 100 | 7 | |
Tenant improvements paid by landlord | ||||||
- | - | 637 | - | - | - | |
Reconciliation of cash, cash equivalents and restricted cash | ||||||
Net (decrease) increase in cash and cash equivalents | ||||||
- | - | - | - | 12,014 | 6,360 | |
Conversion of convertible preferred stock to common stock | ||||||
- | - | - | 48,198 | - | - | |
Conversion of stockholder loan, promissory note and accrued interest | ||||||
- | - | - | - | - | 3,232 | |
Reclassification of deferred initial public offering costs | ||||||
- | - | - | 1,597 | - | - | |
Issuance of warrants to purchase common stock | ||||||
- | - | - | 308 | - | 1,506 | |
Issuance of warrant to purchase Series B preferred stock | ||||||
- | - | - | - | 164 | - | |
Accretion of redeemable convertible preferred stock to redemption value | ||||||
- | - | - | 884 | 525 | 231 | |
Unpaid initial public offering costs in accounts payable and accrued expenses | ||||||
- | - | - | 507 | 410 | 602 | |