| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating activities | ||||||||||||
Net loss | ||||||||||||
-18,277 | -30,770 | -49,312 | -66,648 | -81,615 | -82,818 | 0 | 0 | 0 | - | - | - | - |
Net loss | ||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||
Depreciation | ||||||||||||
203 | 211 | 208 | 202 | 195 | 189 | 188 | 189 | 199 | 182 | 0 | 0 | 0 |
Share-based compensation expense | ||||||||||||
4,366 | 4,612 | 4,635 | 4,951 | 4,894 | 4,785 | 4,567 | 4,170 | 3,750 | 3,364 | 0 | 0 | 0 |
Non-cash interest expense | ||||||||||||
127 | 163 | 188 | 187 | 151 | 154 | 159 | 166 | 208 | 211 | 0 | 0 | 0 |
Accretion of debt discount | ||||||||||||
73 | 67 | 63 | 64 | 78 | 112 | 149 | 186 | 208 | 212 | 0 | 0 | 0 |
Amortization and accretion on available-for-sale investments, net | ||||||||||||
- | 115 | 349 | 619 | 808 | 748 | 551 | 305 | 92 | 31 | 0 | 0 | 0 |
Changes in operating assets and liabilities: | ||||||||||||
Prepaid expenses and other current assets | ||||||||||||
2,045 | 558 | -1,752 | -672 | -1,644 | 505 | 2,394 | 1,424 | -859 | 833 | 0 | 0 | 0 |
Other assets and liabilities | ||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Other assets and liabilities | ||||||||||||
- | - | - | - | - | - | - | 0 | 0 | - | - | - | - |
Other assets | ||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 |
Accounts payable and accrued liabilities | ||||||||||||
-6,654 | -5,582 | -10,533 | -5,656 | -669 | -314 | 5,575 | 5,369 | 4,184 | 4,715 | 0 | 0 | 0 |
Deferred revenue | ||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 |
Deferred rent | ||||||||||||
- | - | - | - | - | - | - | - | 81 | - | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||||||
-17,218 | -27,068 | -53,016 | -66,688 | -76,200 | -79,200 | 0 | 0 | 0 | - | - | - | - |
Investing activities | ||||||||||||
Maturities of available-for-sale investments | ||||||||||||
- | 32,950 | 49,450 | 77,550 | 86,450 | 76,470 | 75,431 | 75,403 | 82,538 | 68,543 | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Purchase of available-for-sale investments | ||||||||||||
- | - | - | - | - | - | - | - | 0 | - | 0 | 0 | 0 |
Acquisition of property and equipment | ||||||||||||
62 | 25 | 0 | 0 | 0 | - | - | - | - | 306 | 0 | 0 | 0 |
Net cash (used in) provided by investing activities | ||||||||||||
1,938 | 32,925 | 49,366 | 49,741 | 14,927 | -3,760 | 0 | 0 | 0 | - | - | - | - |
Financing activities | ||||||||||||
Proceeds from at-the-market sales agreement, net of issuance costs | ||||||||||||
0 | - | - | - | 0 | - | - | - | - | - | - | - | - |
Net cash provided by (used in) investing activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Proceeds from follow-on public offering, net of issuance costs | ||||||||||||
- | - | - | - | - | - | 0 | 0 | 0 | - | 0 | 0 | 0 |
Proceeds from exercise of stock options | ||||||||||||
- | 7 | 38 | 33 | 229 | 465 | 476 | 477 | 400 | 239 | 0 | 0 | 0 |
Principal payments made on long-term debt | ||||||||||||
- | - | - | - | - | 8,300 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | ||||||||||||
3,260 | 8,695 | 10,360 | 7,936 | 9,389 | 81,779 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 |
Net (decrease) increase in cash, cash equivalents and restricted cash | ||||||||||||
-12,020 | 14,552 | 6,710 | -9,011 | -51,884 | -1,181 | -448 | 18,510 | 61,845 | -25,600 | 0 | 0 | 0 |
Supplemental disclosure | ||||||||||||
Tenant improvements paid by landlord | ||||||||||||
- | - | - | - | - | - | - | - | - | 637 | 0 | 0 | 0 |