| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Sep'15 | Jun'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
License and other revenue | ||||||||||||||||||
6,225 | 2,173 | 0 | 0 | 0 | - | - | - | - | - | 0 | 0 | - | - | - | - | - | - | - |
License and collaboration revenue | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | - | - | - |
License revenue | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | 0 | - | 0 |
Operating expenses: | ||||||||||||||||||
Research and development | ||||||||||||||||||
8,502 | 15,658 | 31,839 | 49,194 | 65,879 | 68,291 | 64,740 | 60,707 | 54,842 | 49,053 | 42,089 | 29,721 | 22,456 | 19,455 | 14,793 | 13,258 | 0 | 0 | 0 |
General and administrative | ||||||||||||||||||
15,557 | 16,819 | 17,345 | 17,437 | 15,994 | 14,684 | 12,949 | 11,374 | 10,103 | 9,700 | 9,650 | 8,981 | 7,661 | 6,263 | 4,937 | 6,331 | 0 | 0 | 0 |
Total operating expenses | ||||||||||||||||||
24,059 | 32,477 | 49,184 | 66,631 | 81,873 | 82,975 | 77,689 | 72,081 | 64,945 | 58,753 | 51,739 | 38,702 | 30,117 | 25,718 | 19,730 | 19,589 | 0 | 0 | 0 |
Loss from operations | ||||||||||||||||||
-17,834 | -30,304 | -48,923 | -66,511 | -81,798 | -82,945 | -77,634 | -71,871 | -64,605 | -58,408 | -51,444 | -38,557 | -30,097 | -25,198 | -19,215 | -19,079 | 0 | 0 | 0 |
Other expense | ||||||||||||||||||
-443 | -466 | -389 | -137 | 183 | 127 | -39 | -266 | -604 | -567 | -724 | -920 | -709 | -684 | -456 | -184 | 0 | 0 | 0 |
Net loss | ||||||||||||||||||
-18,277 | -30,770 | -49,312 | -66,648 | -81,615 | -82,818 | -77,673 | -72,137 | -65,209 | -58,975 | -52,168 | -39,477 | -30,806 | -25,882 | -19,671 | -19,263 | 0 | 0 | 0 |
Net loss per share of common stock — basic and diluted | ||||||||||||||||||
-0.07 | -0.04 | -0.17 | -0.15 | -0.45 | -0.67 | -0.75 | -0.65 | -0.62 | -0.66 | -0.72 | -0.54 | -0.41 | 0.98 | -0.28 | -0.62 | -2.05 | -1.31 | -2.36 |
Weighted average shares outstanding — basic and diluted | ||||||||||||||||||
44,753 | 42,488 | 38,414 | 37,636 | 34,144 | 32,112 | 32,024 | 31,979 | 26,818 | 25,347 | 25,338 | 25,309 | 25,250 | 21,046 | 20,493 | 8,243 | 2,660 | 2,651 | 2,216 |
Net loss | ||||||||||||||||||
-18,277 | -30,770 | -49,312 | -66,648 | -81,615 | -82,818 | -77,673 | -72,137 | -65,209 | -58,975 | -52,168 | -39,477 | -30,806 | -25,882 | -19,671 | -19,263 | 0 | 0 | 0 |
Unrealized gain on available-for-sale investments | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | 5 | 0 | 0 | 0 | - | 0 | - | - | - | - |
Comprehensive loss | ||||||||||||||||||
- | - | - | - | - | - | - | - | - | -58,970 | -52,171 | -39,500 | -30,827 | -25,895 | -19,676 | 0 | 0 | 0 | - |