| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 |
|---|---|---|---|---|---|---|---|---|
Marketable Securities, Unrealized Gain (Loss) | ||||||||
- | - | - | - | - | - | - | 2 | - |
Revenues: | ||||||||
Total revenues | ||||||||
12,519 | 7,216 | 4,494 | 5,702 | - | - | - | - | - |
Contract revenue | ||||||||
- | - | - | - | 9,214 | 4,040 | 4,370 | 16,275 | 12,046 |
Collaboration and licensing revenue | ||||||||
- | - | - | - | 1,548 | 0 | 0 | 17,445 | - |
Collaboration and licensing revenue | ||||||||
- | - | - | - | - | - | - | - | 55 |
Total revenues | ||||||||
- | - | - | - | 10,762 | 4,040 | 4,370 | 33,720 | 12,101 |
Operating expenses: | ||||||||
Research and development | ||||||||
42,288 | 55,239 | 49,448 | - | - | - | - | - | - |
Research and development | ||||||||
- | - | - | 58,647 | 97,717 | 45,379 | 24,662 | 30,106 | 30,108 |
General and administrative | ||||||||
21,169 | 23,582 | 27,148 | 25,007 | 31,296 | 17,527 | 8,327 | - | - |
Acquired in-process research and development | ||||||||
65,045 | 0 | 0 | - | - | - | - | - | - |
General and administrative | ||||||||
- | - | - | - | - | - | - | 6,397 | 6,985 |
Total operating expenses | ||||||||
128,502 | 78,821 | 76,596 | 83,654 | 129,013 | 62,906 | 32,989 | 36,503 | - |
Total operating expenses | ||||||||
- | - | - | - | - | - | - | - | 37,093 |
Loss from operations | ||||||||
-115,983 | -71,605 | -72,102 | -77,952 | -118,251 | -58,866 | -28,619 | -2,783 | -24,992 |
Other income: | ||||||||
Unrealized loss on equity investment | ||||||||
- | - | - | 0 | 0 | - | - | - | - |
Interest income and other, net | ||||||||
3,407 | 2,131 | 1,118 | 1,562 | 879 | -446 | -1,232 | -776 | - |
Fair value adjustments to preferred stock warrant liability | ||||||||
- | - | - | - | - | - | 6,590 | 847 | - |
Loss on disposition of assets | ||||||||
- | - | - | - | - | - | -4 | 0 | - |
Interest expense, net | ||||||||
- | - | - | - | - | - | - | - | 212 |
Fair value adjustments to warrant liability | ||||||||
- | - | - | - | - | - | - | - | 385 |
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest | ||||||||
-112,576 | -69,474 | -70,984 | -76,390 | -117,372 | -59,312 | -36,445 | -4,406 | -25,589 |
Accretion of redeemable convertible preferred stock | ||||||||
- | - | - | - | - | - | 34,108 | 4,357 | 9,565 |
Net Income (Loss) Attributable to Parent | ||||||||
- | - | - | - | - | - | -70,553 | -8,763 | -35,154 |
Other comprehensive loss: | ||||||||
Other Comprehensive Income (Loss), Securities, Available-for-sale, Adjustment, after Tax | ||||||||
127 | 871 | -523 | 324 | -799 | 35 | 2 | - | - |
Comprehensive loss | ||||||||
-112,449 | -68,603 | -71,507 | -76,066 | -118,171 | -59,277 | - | - | - |
Net loss | ||||||||
-112,576 | -69,474 | -70,984 | -76,390 | -117,372 | - | - | -4,406 | -25,589 |
Unrealized (loss) gain on securities available-for-sale | ||||||||
- | - | - | - | - | - | - | - | -4 |
Comprehensive loss | ||||||||
- | - | - | - | - | - | -36,443 | -4,404 | -25,593 |
Per share information: | ||||||||
Net loss, basic and diluted (in dollars per share) | ||||||||
-2.03 | -1.43 | -1.51 | -1.65 | -2.67 | -1.80 | -3.65 | -5.75 | -23.49 |
Weighted-average shares outstanding, basic and diluted (in shares) | ||||||||
55,501 | 48,593 | 46,963 | 46,267 | 43,878 | 33,003 | 19,307 | 1,524 | 1,496 |
Contract revenue | ||||||||
Total revenues | ||||||||
7,604 | 7,216 | 4,494 | - | - | - | - | - | - |
License [Member] | ||||||||
Total revenues | ||||||||
4,915 | 0 | 0 | - | - | - | - | - | - |