| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities: | ||||||||
Net loss | ||||||||
-91,568 | -85,550 | -81,286 | -76,075 | -67,249 | -59,925 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation and amortization expense | ||||||||
737 | 758 | 711 | 653 | 595 | 562 | 0 | 0 | 0 |
Stock-based compensation expense | ||||||||
8,156 | 6,910 | 6,494 | 5,790 | 4,680 | 3,952 | 0 | 0 | 0 |
Non-cash interest expense | ||||||||
691 | 507 | 306 | 158 | 30 | 45 | 0 | 0 | 0 |
Amortization and accretion on marketable securities | ||||||||
-642 | -698 | 0 | 0 | 0 | - | - | - | - |
Change in fair value of preferred stock warrant liability | ||||||||
- | - | - | - | - | 110 | 0 | 0 | 0 |
Changes in operating assets and liabilities: | ||||||||
Prepaid expenses and other current assets | ||||||||
122 | 232 | -505 | 389 | 694 | 1,393 | 0 | 0 | 0 |
Operating lease, right-of-use assets | ||||||||
3,260 | 3,308 | 0 | 0 | 0 | - | - | - | - |
Accounts payable | ||||||||
-3,755 | 1,733 | 647 | 4,003 | 3,957 | 2,751 | 0 | 0 | 0 |
Accrued expenses and other current liabilities | ||||||||
6,353 | 4,177 | 4,436 | 3,920 | 3,401 | 5,184 | 0 | 0 | 0 |
Operating lease liabilities | ||||||||
3,055 | 3,161 | 0 | 0 | 0 | - | - | - | - |
Deferred rent | ||||||||
- | - | - | - | - | -127 | 0 | 0 | 0 |
Other assets | ||||||||
- | - | - | - | - | -18 | 0 | 0 | 0 |
Net cash used in operating activities | ||||||||
-79,945 | -72,248 | -68,810 | -62,554 | -55,377 | -48,823 | 0 | 0 | 0 |
Cash flows from investing activities: | ||||||||
Purchase of marketable securities | ||||||||
186,723 | 114,685 | 0 | 0 | 0 | - | - | - | - |
Purchases of property and equipment | ||||||||
503 | 699 | 1,035 | 903 | 689 | 476 | 0 | 0 | 0 |
Proceeds from maturities and sales of marketable securities | ||||||||
0 | - | - | - | - | - | - | - | - |
Net cash used in investing activities | ||||||||
-105,001 | -49,609 | -10,478 | -43,426 | -63,812 | -476 | 0 | 0 | 0 |
Cash flows from financing activities: | ||||||||
Proceeds from issuance of convertible preferred stock, net of issuance costs | ||||||||
- | - | - | - | - | 99,606 | 0 | 0 | 0 |
Proceeds from issuance of long-term debt | ||||||||
- | 29,650 | 0 | 0 | 0 | - | - | - | - |
Payment of debt issuance costs | ||||||||
- | 125 | 0 | 0 | 0 | - | - | - | - |
Payments on long-term debt, including final payment | ||||||||
- | - | - | - | - | 4,698 | 0 | 0 | 0 |
Proceeds from repayment of promissory notes issued upon early exercise of stock options | ||||||||
- | - | - | - | - | 290 | 0 | 0 | 0 |
Payments of initial public offering costs | ||||||||
- | - | - | - | - | 3,638 | 0 | 0 | 0 |
Proceeds from issuance of common stock upon stock option exercises | ||||||||
5,935 | 5,045 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | ||||||||
322,963 | 341,597 | 29,790 | 72,666 | 100,317 | 147,670 | 0 | 0 | 0 |
Net decrease in cash, cash equivalents and restricted cash | ||||||||
138,017 | 219,740 | -49,498 | -33,314 | -18,872 | 98,371 | 0 | 0 | 0 |
Supplemental disclosure of cash flow information: | ||||||||
Interest paid | ||||||||
0 | - | - | - | - | 105 | 0 | 0 | 0 |
Supplemental disclosure of noncash investing and financing information: | ||||||||
Purchases of property and equipment included in accounts payable and accrued expenses | ||||||||
0 | - | - | 0 | 0 | - | - | - | 0 |
Vesting of common stock subject to repurchase | ||||||||
- | - | - | - | - | 4 | 0 | 0 | 0 |
Deferred offering costs included in accounts payable and accrued expenses | ||||||||
- | - | - | - | - | - | 0 | 0 | 0 |