| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Revenues, net: | ||||||||||
Total revenues, net | ||||||||||
10,004 | 10,428 | 9,898 | - | - | - | - | - | - | - | - |
License fees | ||||||||||
- | - | - | - | - | 3,000 | 10,000 | 14,000 | 14,300 | 15,655 | 7,809 |
Royalties | ||||||||||
- | - | - | 7,810 | 8,031 | 6,757 | 3,942 | 1,529 | - | - | - |
Research and development, net | ||||||||||
- | - | - | -283 | -153 | 86 | 1,059 | - | - | - | - |
Research and development, net | ||||||||||
- | - | - | - | - | - | - | 1,442 | 462 | 343 | 780 |
Total revenues | ||||||||||
- | - | - | 7,527 | 7,878 | 9,843 | 15,002 | 16,971 | 14,762 | 15,999 | 8,589 |
Costs and expenses: | ||||||||||
Cost of royalties | ||||||||||
500 | 600 | 496 | 399 | 406 | 339 | 197 | 176 | - | - | - |
Research and development | ||||||||||
22,302 | 24,413 | 45,096 | 31,590 | 26,699 | 13,659 | 12,926 | - | - | - | - |
Research and development | ||||||||||
- | - | - | - | - | - | - | 15,492 | 13,692 | 11,372 | 9,932 |
In-process research and development | ||||||||||
- | - | - | 17,989 | 24,348 | 0 | - | 9,500 | - | - | - |
General and administrative | ||||||||||
11,555 | 14,785 | 14,066 | 15,588 | 12,906 | 11,707 | 11,293 | 10,423 | 8,272 | 10,264 | 8,702 |
Total costs and expenses | ||||||||||
34,360 | 39,761 | 59,658 | 65,566 | 64,359 | 25,705 | 24,418 | 35,591 | 21,965 | 21,637 | 18,634 |
Loss from operations | ||||||||||
-24,356 | -29,333 | -49,760 | -58,039 | -56,481 | -15,862 | -9,416 | -18,619 | -7,202 | -5,637 | -10,044 |
Other expense: | ||||||||||
Loss on debt extinguishment | ||||||||||
-3,495 | 0 | - | - | - | - | - | - | - | - | - |
Interest income | ||||||||||
614 | 684 | 513 | 406 | 277 | 165 | 164 | 149 | 100 | 137 | 222 |
Imputed interest expense related to the sale of future royalties | ||||||||||
4,055 | 0 | - | - | - | - | - | - | - | - | - |
Other expense | ||||||||||
- | - | -104 | -1 | 548 | 0 | - | - | - | - | - |
Interest expense, debt | ||||||||||
791 | 3,926 | 3,966 | 2,777 | 3,325 | 3,749 | 3,841 | 204 | - | - | - |
Change in fair value of warrant liability | ||||||||||
- | - | - | - | - | -717 | -771 | -2,257 | 2,756 | - | - |
Other income (expense), net | ||||||||||
-58 | 0 | -3,557 | -2,372 | -2,500 | -2,867 | -2,905 | - | - | 488 | - |
Change in fair value of warrant liability | ||||||||||
- | - | - | - | - | - | - | - | - | 575 | - |
Total other expense | ||||||||||
-7,785 | -3,242 | - | - | - | - | - | 2,202 | -2,656 | 1,202 | 222 |
Net Income (Loss) Attributable to Parent | ||||||||||
-32,141 | -32,575 | -53,317 | -60,411 | -58,981 | -18,729 | -12,322 | -16,416 | -9,858 | -4,435 | -9,822 |
Net loss per common share (basic and diluted) (USD per share) | ||||||||||
-0.97 | -0.98 | -1.79 | -0.45 | -0.48 | -0.22 | -0.15 | -0.21 | -0.13 | -0.06 | -0.15 |
Weighted average common shares (basic and diluted) (shares) | ||||||||||
33,180 | 33,118 | 29,826 | 132,785 | 123,365 | 85,974 | 82,339 | 79,059 | 76,351 | 74,959 | 65,060 |
Net loss | ||||||||||
-32,141 | -32,575 | -53,317 | -60,411 | -58,981 | -18,729 | -12,322 | -16,416 | -9,858 | -4,435 | -9,822 |
Other comprehensive gain | ||||||||||
Unrealized gain on marketable securities | ||||||||||
0 | 2 | 2 | -32 | 39 | -4 | -22 | - | - | - | - |
Unrealized gain on marketable securities | ||||||||||
- | - | - | - | - | - | - | -18 | -11 | 44 | -90 |
Comprehensive loss | ||||||||||
-32,141 | -32,573 | -53,315 | -60,443 | -58,942 | -18,733 | -12,344 | -16,435 | -9,870 | -4,390 | -9,913 |
Royalties | ||||||||||
Revenue from Contract with Customer, Excluding Assessed Tax | ||||||||||
10,418 | 10,421 | 9,849 | - | - | - | - | - | - | - | - |
Contra revenue, net | ||||||||||
Total revenues, net | ||||||||||
-414 | 7 | - | - | - | - | - | - | - | - | - |
Research and development, net | ||||||||||
Revenue from Contract with Customer, Excluding Assessed Tax | ||||||||||
- | - | 49 | - | - | - | - | - | - | - | - |