| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Operating activities: | ||||||||
Net loss | ||||||||
-58,766 | -50,422 | -44,368 | -37,526 | -30,667 | -27,115 | 0 | 0 | 0 |
Reconciliation of net loss to net cash used in operating activities: | ||||||||
Stock-based compensation | ||||||||
7,413 | 6,294 | 5,310 | 4,231 | 2,922 | 2,320 | 0 | 0 | 0 |
Depreciation and amortization | ||||||||
922 | 887 | 866 | 777 | 623 | 471 | 0 | 0 | 0 |
Noncash lease expense | ||||||||
238 | 226 | 0 | 0 | 0 | - | - | - | - |
Accretion of purchase discounts and amortization, net of premiums on investment securities | ||||||||
1,009 | 1,229 | 0 | 0 | 0 | - | - | - | - |
Other | ||||||||
26 | 4 | 0 | 0 | 0 | - | 0 | 0 | 0 |
Increase (decrease) in cash resulting from changes in: | ||||||||
Prepaid expenses and other current assets | ||||||||
2,463 | 2,221 | 1,555 | 503 | 607 | 1,802 | 0 | 0 | 0 |
Accounts payable and accrued expenses | ||||||||
2,504 | 696 | 2,903 | 3,617 | 6,073 | 7,361 | 0 | 0 | 0 |
Operating lease liability | ||||||||
-665 | -608 | 0 | 0 | 0 | - | - | - | - |
Net cash used in operating activities | ||||||||
-51,852 | -46,381 | -38,943 | -31,029 | -22,811 | -19,459 | 0 | 0 | 0 |
Investing activities: | ||||||||
Purchases of investment securities | ||||||||
99,459 | 108,136 | 0 | 0 | 0 | - | - | - | - |
Maturities of investment securities | ||||||||
133,010 | 150,295 | 0 | 0 | 0 | - | - | - | - |
Purchases of property and equipment | ||||||||
144 | 492 | 746 | 997 | 1,410 | 1,059 | 0 | 0 | 0 |
Net cash provided by investing activities | ||||||||
33,407 | 41,667 | -64,191 | -84,890 | -94,802 | -119,458 | 0 | 0 | 0 |
Financing activities: | ||||||||
Proceeds from issuance of convertible preferred stock, net | ||||||||
- | - | - | - | - | 63,275 | 0 | 0 | 0 |
Proceeds from issuance of common stock, net | ||||||||
0 | - | - | - | - | - | - | - | - |
Proceeds from exercise of stock options | ||||||||
161 | 126 | 109 | 145 | 218 | 451 | 0 | 0 | 0 |
Payment of initial public offering costs | ||||||||
- | - | - | - | - | - | - | 0 | 0 |
Net cash provided by financing activities | ||||||||
6,529 | 67 | 59 | 107,227 | 106,706 | 170,198 | 0 | 0 | 0 |
Net change in cash, cash equivalents and restricted cash | ||||||||
-11,916 | -4,647 | -103,075 | -8,692 | -10,907 | 31,281 | 0 | 0 | 0 |
Noncash investing and financing activities: | ||||||||
Change in unvested stock liability | ||||||||
51 | 94 | -48 | -43 | 77 | 21 | 0 | 0 | 0 |
Amounts accrued for purchases of property and equipment | ||||||||
- | - | - | - | 2 | 42 | 0 | 0 | 0 |
Change in accrued preferred stock issuance and initial public offering costs | ||||||||
- | - | - | - | - | - | - | - | 0 |