| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Collaboration revenue | ||||||
289,590 | 3,124 | 40,997 | 5,164 | 247 | - | |
Operating expenses: | ||||||
Research and development | ||||||
179,362 | 113,773 | 69,800 | 42,238 | 12,573 | 1,513 | |
General and administrative | ||||||
63,488 | 48,294 | 35,845 | 31,056 | 13,403 | 5,114 | |
Total operating expenses | ||||||
242,850 | 162,067 | 105,645 | 73,294 | 25,976 | 6,627 | |
Loss from operations | ||||||
46,740 | -158,943 | -64,648 | -68,130 | -25,729 | -6,627 | |
Other income (expense): | ||||||
Interest expense | ||||||
- | - | - | -8,050 | -108 | - | |
Loss from equity method investment | ||||||
-5,467 | -4,275 | -1,763 | -36,532 | - | - | |
Gain on extinguishment of convertible loan | ||||||
- | - | - | 11,482 | - | - | |
Other income (expense), net | ||||||
26,033 | -1,210 | -197 | 78,512 | 16 | -236 | |
Total other income, net | ||||||
20,566 | -5,485 | -1,960 | 45,412 | -92 | -236 | |
Net loss before income taxes | ||||||
67,306 | -164,428 | -66,608 | -22,718 | -25,821 | -6,863 | |
Provision for income taxes | ||||||
448 | 553 | 1,749 | 484 | 7 | -63 | |
Net loss | ||||||
- | - | - | -23,202 | -25,828 | -6,800 | |
Net loss | ||||||
66,858 | -164,981 | -68,357 | -23,177 | -25,503 | -7,009 | |
Loss attributable to noncontrolling interest | ||||||
- | - | - | -25 | -325 | -536 | |
Loss on extinguishment of redeemable convertible preferred shares | ||||||
- | - | - | - | - | -745 | |
Net loss | ||||||
- | - | - | -23,202 | -25,828 | -6,800 | |
Foreign currency translation adjustment | ||||||
15 | -22 | 40 | -18 | -6 | -2 | |
Comprehensive loss | ||||||
66,873 | -165,003 | -68,317 | -23,220 | -25,834 | -6,802 | |
Reconciliation of net income (loss) to net income (loss) attributable to common shareholders: | ||||||
Net income (loss) per share attributable to common shareholders— basic | ||||||
1.23 | -3.44 | -1.71 | - | - | - | |
Weighted-average common shares outstanding used in net income (loss) per share attributable to common shareholders—basic | ||||||
54,392 | 47,964 | 40,057 | - | - | - | |
Net income (loss) per share attributable to common shareholders— diluted | ||||||
1.17 | -3.44 | -1.71 | - | - | - | |
Weighted-average common shares outstanding used in net income (loss) per share attributable to common shareholders—diluted | ||||||
56,932 | 47,964 | 40,057 | - | - | - | |
Net loss per share attributable to common shareholders—basic and diluted | ||||||
- | - | - | -1.89 | -5.06 | 1.97 | |
Weighted-average common shares outstanding used in net loss per share attributable to common shareholders—basic and diluted | ||||||
- | - | - | 12,257 | 5,037 | 3,559 | |