| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Sep'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collaboration revenue | |||||||||||||||||
157 | 77,016 | 211,928 | 318 | 328 | 115 | 563 | 1,088 | 1,358 | 32,325 | 2,387 | 3,582 | 2,703 | 2,344 | 1,549 | 795 | 476 | - |
Operating expenses: | |||||||||||||||||
Research and development | |||||||||||||||||
54,193 | 48,761 | 57,246 | 39,533 | 33,822 | 28,801 | 39,820 | 25,633 | 19,519 | 20,030 | 17,845 | 17,120 | 14,805 | 15,572 | 12,052 | 8,602 | 6,012 | 3,749 |
General and administrative | |||||||||||||||||
19,550 | 17,272 | 15,519 | 15,768 | 14,929 | 16,542 | 10,175 | 12,741 | 8,836 | 11,323 | 8,112 | 7,768 | 8,642 | 12,082 | 4,107 | 8,751 | 6,116 | 2,453 |
Total operating expenses | |||||||||||||||||
73,743 | 66,033 | 72,765 | 55,301 | 48,751 | 45,343 | 49,995 | 38,374 | 28,355 | 31,353 | 25,957 | 24,888 | 23,447 | 27,654 | 16,159 | 17,353 | 12,128 | 6,202 |
Loss from operations | |||||||||||||||||
-73,586 | 10,983 | 139,163 | -54,983 | -48,423 | -45,228 | -49,432 | -37,286 | -26,997 | 972 | -23,570 | -21,306 | -20,744 | -25,310 | -14,610 | -16,558 | -11,652 | -6,202 |
Other income (expense): | |||||||||||||||||
Interest expense | |||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 1 | -1 | 0 | -8,050 | -8 |
Loss from equity method investment | |||||||||||||||||
- | 0 | -3,430 | -1,012 | -1,025 | -1,019 | -1,012 | -1,153 | -1,091 | -453 | -359 | -505 | -446 | - | - | -686 | - | - |
Other income, net | |||||||||||||||||
4,232 | - | - | - | 1,125 | - | - | - | - | - | - | - | - | - | - | - | - | - |
Gain on extinguishment of convertible loan | |||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 11,482 | - |
Other income (expense), net | |||||||||||||||||
- | - | 2,964 | 2,381 | - | -1,109 | -130 | 155 | -126 | 41 | -71 | -161 | -6 | 78,653 | -75 | 80 | -146 | 9 |
Total other income, net | |||||||||||||||||
4,232 | 19,563 | -466 | 1,369 | 100 | -2,128 | -1,142 | -998 | -1,217 | -412 | -430 | -666 | -452 | 42,808 | -76 | -606 | 3,286 | 1 |
Net loss before income taxes | |||||||||||||||||
-69,354 | 30,546 | 138,697 | -53,614 | -48,323 | -47,356 | -50,574 | -38,284 | -28,214 | 560 | -24,000 | -21,972 | -21,196 | 17,498 | -14,686 | -17,164 | -8,366 | -6,201 |
Provision for income taxes | |||||||||||||||||
400 | -52 | 300 | 100 | 100 | 267 | 100 | 100 | 86 | 420 | 707 | 343 | 279 | 400 | 8 | 0 | 76 | 153 |
Net loss | |||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -21,475 | 17,098 | -14,694 | -17,164 | -8,442 | -6,354 |
Net loss | |||||||||||||||||
-69,731 | 30,542 | 138,423 | -53,699 | -48,408 | -47,590 | -50,711 | -38,380 | -28,300 | - | -24,707 | -22,315 | - | 17,099 | -14,680 | -17,157 | -8,439 | -6,353 |
Loss attributable to noncontrolling interest | |||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | -1 | -14 | -7 | -3 | -1 |
Net loss | |||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -21,475 | 17,098 | -14,694 | -17,164 | -8,442 | -6,354 |
Foreign currency translation adjustment | |||||||||||||||||
-25 | 29 | -12 | -10 | 8 | -7 | -6 | -21 | 12 | 2 | 8 | 6 | 24 | 0 | -1 | -13 | -4 | -4 |
Comprehensive loss | |||||||||||||||||
-69,756 | 30,571 | 138,411 | -53,709 | -48,400 | -47,597 | -50,717 | -38,401 | -28,288 | 142 | -24,699 | -22,309 | -21,451 | 17,098 | -14,695 | -17,177 | -8,446 | -6,358 |
Reconciliation of net income (loss) to net income (loss) attributable to common shareholders: | |||||||||||||||||
Net income (loss) per share attributable to common shareholders— basic | |||||||||||||||||
- | 0.53 | 2.52 | - | - | - | -1.07 | - | - | - | - | - | - | - | - | - | - | - |
Weighted-average common shares outstanding used in net income (loss) per share attributable to common shareholders—basic | |||||||||||||||||
- | 57,395 | 54,829 | - | - | - | 47,391 | - | - | - | - | - | - | - | - | - | - | - |
Net income (loss) per share attributable to common shareholders— diluted | |||||||||||||||||
- | 0.51 | 2.40 | - | - | - | -1.07 | - | - | - | - | - | - | - | - | - | - | - |
Weighted-average common shares outstanding used in net income (loss) per share attributable to common shareholders—diluted | |||||||||||||||||
- | 60,233 | 57,598 | - | - | - | 47,391 | - | - | - | - | - | - | - | - | - | - | - |
Net loss per share attributable to common shareholders—basic and diluted | |||||||||||||||||
-1.15 | - | - | -1.01 | -0.93 | - | - | -0.82 | -0.62 | - | -0.62 | -0.56 | -0.54 | 5.56 | -2.77 | -3.15 | -1.53 | -1.15 |
Weighted-average common shares outstanding used in net loss per share attributable to common shareholders—basic and diluted | |||||||||||||||||
60,847 | - | - | 53,188 | 52,093 | - | - | 46,842 | 45,877 | - | 40,088 | 39,895 | 39,725 | 32,760 | 5,292 | 5,448 | 5,528 | 5,528 |