| Dec'19 | Dec'18 | Dec'17 | Dec'16 | |||
|---|---|---|---|---|---|---|
Collaboration revenue: | ||||||
Collaboration revenue from customers | ||||||
26,678 | 129,160 | 0 | 0 | |||
Operating expenses: | ||||||
Research and development | ||||||
193,382 | 143,183 | 74,460 | 75,702 | |||
General and administrative | ||||||
46,480 | 32,349 | 15,680 | 11,731 | |||
Total operating expenses | ||||||
239,862 | 175,532 | 90,140 | 87,433 | |||
Loss from operations | ||||||
-213,184 | -46,372 | -90,140 | -87,433 | |||
Interest and other income, net | ||||||
15,219 | 10,132 | 1,955 | 781 | |||
Loss before income taxes | ||||||
-197,965 | -36,240 | -88,185 | - | |||
Income tax benefit | ||||||
-400 | 0 | 0 | - | |||
Net loss | ||||||
-197,614 | -36,240 | -88,185 | -86,652 | |||
Other comprehensive income (loss): | ||||||
Net unrealized gain on marketable securities, net of tax | ||||||
999 | -281 | 5 | -373 | |||
Comprehensive loss | ||||||
-196,615 | -36,521 | -88,180 | -87,025 | |||
Net loss per share, basic and diluted (usd per share) | ||||||
-2.07 | -0.39 | -5.89 | -13.49 | |||
Weighted average number of shares outstanding, basic and diluted (in shares) | ||||||
95,608 | 92,621 | 14,964 | 6,424 | |||