| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | |
|---|---|---|---|---|---|---|
Collaboration and other research and development revenues | ||||||
20,531 | 31,937 | 13,728 | 6,053 | 1,629 | - | |
Operating expenses: | ||||||
Research and development | ||||||
96,898 | 90,654 | 83,159 | 56,979 | 18,846 | 5,073 | |
General and administrative | ||||||
64,555 | 55,010 | 50,502 | 46,262 | 18,095 | 7,650 | |
Total operating expenses | ||||||
161,453 | 145,664 | 133,661 | 103,241 | 36,941 | 12,723 | |
Operating loss | ||||||
-140,922 | -113,727 | -119,933 | -97,188 | -35,312 | -12,723 | |
Other income, net: | ||||||
Other income (expense), net | ||||||
-137 | 328 | 587 | -57 | -37,445 | -928 | |
Interest income, net | ||||||
7,313 | 3,445 | -978 | 62 | -143 | -34 | |
Total other income, net | ||||||
7,176 | 3,773 | -391 | 5 | -37,588 | -962 | |
Net loss | ||||||
-133,746 | -109,954 | -120,324 | -97,183 | -72,900 | -13,685 | |
Accretion of redeemable convertible preferred stock to redemption value | ||||||
- | - | - | 47 | 394 | 309 | |
Net loss attributable to common stockholders | ||||||
-133,746 | -109,954 | -120,324 | -97,230 | -73,294 | -13,994 | |
Net loss per share attributable to common stockholders, basic and diluted | ||||||
-2.68 | -2.33 | -2.98 | -3.02 | -28.55 | -12.46 | |
Weighted-average common shares outstanding, basic and diluted | ||||||
49,983 | 47,097 | 40,323 | 32,219 | 2,566 | 1,123 | |