Epizyme, inc. (EPZM)
CashFlow / TTM
Mar'20Dec'19Sep'19Jun'19Mar'19Dec'18Sep'18Jun'18Mar'18Dec'17Sep'17Jun'17Mar'17Dec'16Sep'16Jun'16Mar'16Dec'15Sep'15Jun'15Mar'15Dec'14Sep'14Jun'14Mar'14Dec'13Sep'13Jun'13Mar'13
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss

-191,893

-170,295

-136,838

-138,241

-118,904

-123,630

-136,851

-136,956

-135,852

-134,309

-133,159

-119,898

-119,855

-110,212

-97,422

-96,151

-93,929

-132,376

-125,185

-121,820

-109,447

-55,005

-24,040

-14,044

-2,870

-3,483

0

0

0

Adjustments to reconcile net loss to net cash used in operating activities:
Acquired in-process research and development

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

40,000

0

0

0

-

-

-

0

-

-

-

-

Depreciation and amortization

1,105

800

922

934

946

1,100

1,213

1,397

1,589

1,639

1,630

1,622

1,611

1,589

1,550

1,557

1,548

1,419

1,252

1,033

833

742

717

702

693

703

0

0

0

Stock-based compensation

21,315

18,016

14,106

13,632

12,328

12,004

12,272

11,964

11,561

11,431

11,398

11,220

10,952

10,568

9,926

10,065

9,806

9,849

9,952

8,679

7,817

6,864

5,678

4,964

3,947

2,819

0

0

0

Amortization of discount on investments

2,755

3,175

3,219

2,750

2,140

1,556

624

231

-177

-265

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Amortization of debt discount

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Loss on disposal of property and equipment

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Non-cash interest expense associated with the sale of future royalties

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Loss on disposal of property and equipment

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-27

0

0

0

-

-

-

-

-

-

-

-

Changes in operating assets and liabilities:
Accounts receivable

-11,328

-17,500

-343

13,274

12,954

19,686

12,319

-25

16

359

-6,175

-35

-168

-239

6,023

-663

-189

-1,813

-1,932

-1,468

-7,786

-31,592

-46

-5,617

6,249

31,838

0

0

0

Inventory

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Prepaid expenses and other current assets

7,412

3,359

9,068

5,592

6,300

3,181

-2,798

109

227

2,525

4,328

394

2,782

1,542

2,538

5,562

2,933

1,638

-769

-645

457

419

1,032

524

1,137

1,495

0

0

0

Accounts payable

-2,501

3,389

-1,130

-4,300

544

-2,404

900

1,355

280

1,967

1,973

5,921

4,671

341

415

585

-2,863

-3,647

-2,824

-1,459

1,731

3,611

2,384

1,209

-1,204

1,641

0

0

0

Accrued expenses

2,682

2,897

-1,162

-525

-2,061

2,066

3,195

2,004

4,953

1,523

5,810

5,204

2,703

4,673

-696

1,466

4,533

4,292

3,429

3,254

367

411

3,272

1,855

850

2,304

0

0

0

Deferred revenue

-

-13,300

0

0

0

-

-

-

-

-

-

-

-

-1,900

-1,977

8,142

8,017

7,558

-1,886

-15,862

-19,007

-23,721

-17,556

-19,452

-21,990

-22,573

0

0

0

Operating lease assets

10,131

9,921

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Operating lease liabilities

10,851

10,043

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Other assets

0

-

0

0

0

-

18

15

49

17

-1

30

15

-106

61

-74

-23

178

-351

-301

-489

-606

-509

-509

-432

433

0

0

0

Other liabilities

-

-

-

-

-

-

363

420

413

320

115

0

-116

-182

-148

-119

-72

-44

-78

-65

-69

-46

-81

-219

-1,307

-1,379

0

0

0

Acquisition of in-process research and development

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

40,000

0

0

0

-

-

-

0

-

-

-

-

Net cash used in operating activities

-173,874

-147,168

-134,237

-131,824

-122,821

-121,600

-129,439

-132,514

-117,539

-120,433

-111,017

-97,369

-104,160

-96,371

-97,004

-79,286

-75,660

-72,925

-72,281

-83,818

-69,949

-35,363

-30,103

-19,383

-28,835

-53,734

0

0

0

Purchases of available-for-sale securities

0

-

0

0

0

-

0

0

0

-

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Maturities of available-for-sale securities

0

-

0

0

0

-

0

0

0

-

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Purchase of intangible asset

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Purchases of property and equipment

636

594

570

380

212

299

399

410

974

984

941

988

672

624

415

273

90

183

1,174

1,621

2,063

2,216

1,630

1,224

906

630

0

0

0

Net cash provided by (used in) investing activities

6,648

-85,320

-82,075

-134,689

-107,175

-102,606

-26,644

-43,156

28,150

113,330

108,945

93,369

-148,047

-165,414

-198,191

-199,714

-90

-40,183

-41,174

-41,621

-42,063

-2,216

-1,630

-1,224

-906

-630

0

0

0

CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of common stock, net of commissions

-

122,991

0

0

0

-

-

-

-

152,922

153,291

1,958

1,958

130,438

130,067

130,067

143,749

130,712

130,712

130,712

117,030

101,283

0

0

0

-

-

-

-

Proceeds from issuance of preferred stock, net of commissions

-

37,432

0

0

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Payment of offering costs

341

284

0

0

0

-

-

-

-

-

-

-

-

483

374

374

711

367

367

367

211

649

689

1,462

3,279

2,849

0

0

0

Proceeds from the issuance of debt

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Payment of debt issuance costs

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Proceeds from the issuance of common stock in connection with the exercise of the put option, net of financing costs

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Proceeds from reimbursement of common stock offering costs

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

269

0

0

0

-

-

-

-

Payment under capital lease obligation

-

-

-

-

-

129

289

446

580

620

605

590

576

561

548

534

521

441

0

0

0

-

-

-

-

-

-

-

-

Proceeds from stock options exercised

4,612

2,358

1,984

2,020

1,271

1,885

2,466

3,757

4,140

3,281

2,582

1,219

2,089

1,589

1,766

2,279

1,038

996

1,263

1,617

2,185

2,736

2,454

1,443

759

277

0

0

0

Issuance of shares under employee stock purchase plan

1,027

741

740

680

680

779

777

789

790

677

679

571

570

374

374

347

347

436

436

492

492

454

0

0

0

-

-

-

-

Net cash provided by financing activities

203,230

286,346

244,543

244,539

244,012

84,213

2,568

155,047

155,297

155,872

155,838

3,049

3,932

131,357

131,285

131,785

143,902

131,336

131,724

132,262

119,458

104,110

103,827

101,790

181,752

79,947

0

0

0

Net increase in cash, cash equivalents and restricted cash

36,004

53,858

28,231

-21,974

14,016

-139,993

-153,515

-20,623

65,908

148,769

153,766

-951

-248,275

-130,428

-163,910

-147,215

68,152

18,228

18,269

6,823

7,446

66,531

72,094

81,183

152,011

25,583

0

0

0

SUPPLEMENTAL CASH FLOW INFORMATION:
Equipment acquired under capital lease

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1,732

0

0

0

-

-

-

-

-

-

-

-

Unpaid offering costs

-

-

-

-

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

-

-

-

0

-

0

0

0

Interest paid

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Property and equipment included in accounts payable or accruals

0

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Accretion of redeemable convertible preferred stock to redemption value

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

264

0

0

0

Cash paid for income taxes

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

0

0

-

-

-

-

Purchases of property and equipment unpaid at period end

-

-

-

-

-

-

-

0

0

-

-

-

0

-

-

-

-

-

-

-

-

-

-

0

0

-

0

0

0