| Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|
Revenue from product sales | ||||||||
- | - | 337 | 270 | 170 | 200 | 153 | - | 936 |
Collaboration revenue | ||||||||
- | - | 18 | 222 | 10 | 0 | - | - | - |
Total revenues | ||||||||
0 | 0 | 355 | 492 | 180 | 200 | - | - | - |
License fees | ||||||||
- | - | - | - | - | - | - | - | 0 |
Total revenue | ||||||||
- | - | - | - | - | - | - | - | 936 |
Cost of product sales | ||||||||
- | - | 696 | 426 | 2,312 | 7,501 | 7,804 | 13 | 502 |
Cost of collaboration revenue | ||||||||
- | - | 1 | 296 | 0 | 0 | - | - | - |
Total cost of revenue | ||||||||
- | - | 697 | 722 | 2,312 | 7,501 | - | - | - |
Gross profit (loss) | ||||||||
- | - | -342 | -230 | -2,132 | -7,301 | -7,651 | -13 | 433 |
Research and development expense | ||||||||
6,018 | 6,512 | 8,400 | 9,968 | 8,342 | 3,638 | 10,193 | 7,171 | 5,486 |
Selling, general and administrative expense | ||||||||
6,405 | 6,749 | 9,773 | 11,285 | 10,087 | 9,440 | 11,546 | 12,795 | 6,515 |
Total operating expenses | ||||||||
12,389 | 18,981 | - | - | - | - | - | - | - |
Intangible asset impairment expense | ||||||||
- | - | 3,905 | 0 | - | - | - | - | - |
Restructuring costs | ||||||||
- | - | 335 | 0 | - | - | - | - | - |
Operating income (loss) | ||||||||
-12,389 | -18,981 | -26,479 | -37,407 | -29,954 | -30,503 | -29,390 | -19,979 | -11,568 |
Other income (expense): | ||||||||
Warrant revaluation income | ||||||||
- | - | - | 2,929 | 3,930 | -1,053 | - | - | - |
Warrant revaluation income | ||||||||
921 | 4,920 | 11,884 | - | - | - | - | - | - |
Warrant revaluation and other finance income (expense) | ||||||||
- | - | - | - | - | - | 20,404 | 2,562 | -465 |
Derivative revaluation income (expense) | ||||||||
1,700 | -1,407 | -462 | 0 | - | - | -23 | -5,452 | 0 |
Interest expense | ||||||||
771 | 828 | 228 | 0 | - | - | - | 1,062 | 1,045 |
Reorganization items, net | ||||||||
- | - | - | - | - | - | - | - | -3 |
Other income (expense), net | ||||||||
- | - | - | 25 | - | - | - | - | 244 |
Loss on extinguishment of debt | ||||||||
- | - | - | - | - | - | -5,617 | - | - |
Other income | ||||||||
- | - | - | - | 368 | 0 | 0 | - | - |
Other income, net | ||||||||
300 | 56 | -7 | - | 6 | 2 | -1,017 | - | - |
Interest income | ||||||||
- | - | - | - | - | - | - | - | 0 |
Income (loss) before income taxes | ||||||||
-10,277 | -16,240 | -15,292 | -34,453 | -25,650 | -31,554 | - | -23,931 | - |
Income tax benefit | ||||||||
0 | 0 | 0 | 0 | 0 | 0 | - | - | 0 |
Loss from continuing operations | ||||||||
- | - | - | - | - | - | -13,143 | - | -12,830 |
Loss from discontinued operations, net of tax | ||||||||
- | - | - | - | - | - | -11 | -94 | -48 |
Gain on sale of discontinued operations, net of tax | ||||||||
- | - | - | - | - | - | 467 | - | - |
Net Income (Loss) Attributable to Parent | ||||||||
-10,300 | -16,240 | -15,292 | -34,453 | -25,650 | -31,554 | -12,687 | -24,025 | - |
Redeemable Preferred Stock Dividends | ||||||||
336 | 264 | 0 | - | - | - | - | - | - |
Preferred Stock, Deemed Dividend | ||||||||
513 | 4,099 | 0 | - | - | - | - | - | - |
Net loss | ||||||||
- | - | - | - | - | - | - | - | -12,879 |
Net loss attributable to non-controlling interest | ||||||||
- | - | - | - | - | - | 24 | 18 | 51 |
Deemed dividend associated with beneficial conversion | ||||||||
- | - | - | - | - | - | - | - | 0 |
Preferred stock dividends | ||||||||
- | - | - | - | - | - | - | - | 0 |
Net income (loss) attributable to common stockholders | ||||||||
-11,126 | -20,603 | -15,292 | - | - | - | -12,711 | -24,043 | -12,931 |
Loss from continuing operations before income taxes | ||||||||
- | - | - | - | - | - | -15,643 | -23,931 | -12,830 |
Deferred tax benefit | ||||||||
- | - | - | - | - | - | -2,500 | - | - |
Per Share Information: | ||||||||
Loss from continuing operations - basic | ||||||||
- | - | - | - | - | - | -1.47 | -10.91 | - |
Loss from discontinued operations, net of tax - basic (in dollars per share) | ||||||||
- | - | - | - | - | - | - | -0.04 | - |
Gain on sale of discontinued operations, net of tax - basic | ||||||||
- | - | - | - | - | - | 0.05 | - | - |
Net loss attributable to non-controlling interest, basic (in dollars per share) | ||||||||
- | - | - | - | - | - | - | -0.01 | - |
Earnings Per Share, Basic | ||||||||
-1.45 | -6.66 | -1.04 | -0.82 | -0.63 | -1.06 | -1.42 | -10.96 | - |
Loss from continuing operations - diluted | ||||||||
- | - | - | - | - | - | -2.65 | -10.99 | - |
Loss from discontinued operations, net of tax - diluted (in dollars per share) | ||||||||
- | - | - | - | - | - | - | -0.04 | - |
Gain on sale of discontinued operations, net of tax - diluted | ||||||||
- | - | - | - | - | - | 0.05 | - | - |
Net loss attributable to non-controlling interest, diluted (in dollars per share) | ||||||||
- | - | - | - | - | - | - | -0.01 | - |
Earnings Per Share, Diluted | ||||||||
-1.45 | -6.67 | -1.18 | -0.85 | -0.70 | -1.12 | -2.60 | -11.04 | - |
Loss from continuing operations - basic and diluted (in dollars per share) | ||||||||
- | - | - | - | - | - | - | - | -0.68 |
Weighted average number of common shares outstanding: | ||||||||
Weighted Average Number of Shares Outstanding, Basic | ||||||||
7,693 | 3,092 | 14,641 | 42,178 | 40,789 | 29,830 | 8,965 | 2,194 | - |
Weighted Average Number of Shares Outstanding, Diluted | ||||||||
7,693 | 3,093 | 14,647 | 42,351 | 40,969 | 30,196 | 9,147 | 2,240 | - |
Loss from discontinued operations - basic and diluted | ||||||||
- | - | - | - | - | - | - | - | 0.00 |
Deemed dividend associated with beneficial conversion of preferred stock | ||||||||
- | - | - | - | - | - | - | - | 0.00 |
Preferred stock dividends | ||||||||
- | - | - | - | - | - | - | - | 0.00 |
Net loss attributable to common shareholders per common share - basic and diluted | ||||||||
- | - | - | - | - | - | - | - | -0.68 |
Weighted average number of basic and diluted common shares outstanding | ||||||||
- | - | - | - | - | - | - | - | 18,757 |
Affiliated Entity | ||||||||
Research and development expense | ||||||||
-34 | 5,720 | - | - | - | - | - | - | - |