| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|---|---|---|---|---|---|---|---|---|---|
Operating activities | ||||||||||
Net Income (Loss) Attributable to Parent | ||||||||||
-64,790 | -59,013 | -60,535 | -75,985 | -53,315 | -52,830 | -16,526 | -19,024 | -22,470 | -16,902 | -19,128 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||
Depreciation and amortization | ||||||||||
4,605 | 5,372 | 7,409 | 6,738 | 4,915 | 4,061 | 2,551 | 2,191 | 1,410 | 1,140 | 1,632 |
Stock-based compensation expense | ||||||||||
11,393 | 11,023 | 9,092 | 13,858 | 16,830 | 20,940 | 6,438 | 4,088 | 2,799 | 1,586 | 2,111 |
Acquisition-related share-based awards acceleration expense | ||||||||||
- | - | - | - | - | 2,648 | 0 | 0 | - | - | - |
Amortization of Intangible Assets | ||||||||||
11,200 | 11,200 | 11,200 | 11,200 | 11,200 | 9,800 | 0 | 0 | - | - | - |
Amortization of debt discounts, premiums and issuance costs | ||||||||||
1,936 | 8,379 | 287 | 278 | - | - | - | - | - | - | - |
Impairment of intangible | ||||||||||
443 | 0 | 0 | - | - | - | - | - | - | - | - |
Gain (Loss) on Extinguishment of Debt | ||||||||||
-12,020 | 0 | 0 | - | - | - | - | - | - | - | - |
Provision for excess and obsolete inventory | ||||||||||
1,449 | 1,026 | 434 | - | - | - | - | - | - | - | - |
Loss from changes in the fair value of convertible preferred stock warrants, net | ||||||||||
- | - | - | - | - | - | - | - | -1,483 | -445 | -135 |
Loss on disposal of property and equipment | ||||||||||
-89 | -141 | -135 | -87 | -87 | -83 | -296 | -26 | 0 | 10 | 97 |
Non-cash charges for sale of inventory revalued at the date of acquisition | ||||||||||
- | - | - | - | - | 856 | 0 | 0 | - | - | - |
Other non-cash items | ||||||||||
-316 | 175 | -890 | -26 | 137 | 0 | - | - | - | - | - |
Gain from escrow settlement | ||||||||||
- | - | - | - | 3,986 | 0 | 0 | - | - | - | - |
Gain from sale of investment in Verinata | ||||||||||
- | - | - | - | 2,330 | 332 | 1,777 | 0 | 0 | - | - |
Gain from extinguishment of convertible preferred stock warrants | ||||||||||
- | - | - | - | - | - | - | - | 765 | 0 | 0 |
Write-off of debt discount upon note repayment | ||||||||||
- | - | - | - | - | - | - | - | 1,157 | 0 | 0 |
Amortization of debt discount and issuance cost | ||||||||||
- | - | - | - | - | - | - | - | 182 | 364 | 308 |
Gain from sublicense of technology | ||||||||||
- | - | - | - | - | - | - | - | - | - | 1,807 |
Changes in assets and liabilities: | ||||||||||
Accounts receivable, net | ||||||||||
2,075 | 1,788 | 554 | -10,521 | 2,762 | 3,393 | -2,412 | 3,702 | 1,222 | -209 | 3,999 |
Inventories | ||||||||||
2,689 | -462 | -4,162 | 3,387 | 3,741 | 6,162 | 1,533 | 1,682 | 1,077 | 961 | -1,510 |
Prepaid expenses and other assets | ||||||||||
1,400 | -178 | -1,583 | 457 | 1,127 | 52 | 882 | -201 | 471 | 1,013 | -91 |
Accounts payable | ||||||||||
2,145 | -294 | 585 | -2,271 | 769 | 107 | 1,802 | -1,815 | 540 | 932 | -637 |
Deferred revenue | ||||||||||
2,129 | 2,574 | 1,636 | -274 | 2,613 | 3,191 | 1,640 | 449 | 916 | 746 | -707 |
Other liabilities | ||||||||||
-11,349 | -4,636 | 1,358 | 580 | -4,023 | -1,540 | 3,988 | 1,790 | -24 | 1,956 | 1,075 |
Net cash used in operating activities | ||||||||||
-35,210 | -25,201 | -24,098 | -39,138 | -34,733 | -22,623 | -1,591 | -17,478 | -17,542 | -11,508 | -19,513 |
Investing activities | ||||||||||
Acquisition, net of cash acquired | ||||||||||
- | - | - | - | - | 113,190 | 0 | 0 | - | - | - |
Purchases of investments | ||||||||||
62,370 | 1,450 | 6,276 | 38,594 | 66,973 | 132,644 | 59,436 | 35,385 | 71,379 | 0 | 0 |
Proceeds from maturities of investments | ||||||||||
25,600 | 6,541 | 25,550 | 86,431 | 103,369 | 74,520 | 33,440 | 51,770 | 29,966 | 0 | 0 |
Proceeds from sale of investment in Verinata | ||||||||||
- | - | - | 2,330 | 0 | 332 | 3,117 | 0 | 0 | - | - |
Purchases of intangible assets | ||||||||||
0 | 0 | 50 | 0 | 6,670 | 0 | 1,240 | 0 | 0 | 0 | 0 |
Purchases of property and equipment | ||||||||||
2,531 | 372 | 1,566 | 5,065 | 3,982 | 7,403 | 3,446 | 2,384 | 1,676 | 1,539 | 799 |
License agreement rights | ||||||||||
- | - | - | - | - | - | - | - | 2,000 | - | - |
Proceeds from disposal of property and equipment | ||||||||||
- | - | - | - | - | - | - | - | - | 10 | 111 |
Decrease in restricted cash | ||||||||||
- | - | - | - | - | - | - | - | 21 | -196 | 0 |
Net cash provided by (used in) investing activities | ||||||||||
-39,301 | 4,719 | 17,658 | 45,102 | 25,744 | -178,385 | -27,565 | 14,001 | -45,110 | -1,333 | -688 |
Financing activities | ||||||||||
Proceeds from issuance of convertible notes, net | ||||||||||
- | - | - | - | - | 195,213 | 0 | 0 | - | - | 10,510 |
Proceeds from issuance of common stock | ||||||||||
0 | 59,469 | 28,793 | 0 | 0 | - | 0 | 56,008 | 76,946 | 0 | 0 |
Proceeds from debt issuance | ||||||||||
55,000 | 0 | 0 | - | - | - | - | - | - | - | - |
Proceeds from exercise of convertible preferred stock warrants and issuance of convertible preferred stock, net of issuance costs | ||||||||||
- | - | - | - | - | - | - | - | - | 633 | 0 |
Proceeds from issuance of convertible preferred stock, net of issuance costs | ||||||||||
- | - | - | - | - | - | - | - | - | - | 7,410 |
Proceeds from note | ||||||||||
- | - | - | - | - | - | - | - | 5,000 | 0 | 0 |
Repayment of note | ||||||||||
- | - | - | - | - | - | - | - | 5,000 | 0 | 0 |
Repayment of long-term debt | ||||||||||
51,826 | 0 | 0 | - | - | - | 0 | 10,190 | 4,742 | 0 | 1,034 |
Payments of debt issuance cost | ||||||||||
1,888 | 2,862 | 0 | 0 | - | - | - | - | - | - | - |
Proceeds from exercise of stock options | ||||||||||
1,058 | 208 | 100 | 227 | 5,491 | 5,113 | 5,806 | 2,703 | 1,288 | 39 | 53 |
Proceeds from stock issuance from ESPP | ||||||||||
1,075 | 1,203 | 222 | 0 | - | - | - | - | - | - | - |
Payments for taxes related to net share settlement of equity awards and other | ||||||||||
629 | 358 | 118 | 111 | 151 | - | - | - | - | - | - |
Proceeds from line of credit | ||||||||||
- | - | - | - | - | - | 0 | 1,875 | 0 | 3,125 | 0 |
Repayment of line of credit | ||||||||||
- | - | - | - | - | - | 0 | 1,875 | 3,125 | 0 | 0 |
Net cash provided by (used in) financing activities | ||||||||||
2,790 | 57,660 | 28,997 | 116 | 5,340 | 200,326 | 5,806 | 48,521 | 70,367 | 3,797 | 16,939 |
Effect of foreign exchange rate fluctuations on cash and cash equivalents | ||||||||||
56 | 167 | 454 | -152 | -947 | -866 | -38 | 52 | 115 | 165 | 68 |
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||||||
-71,665 | 37,345 | 23,011 | 5,928 | -4,596 | -1,548 | -23,388 | 45,096 | 7,830 | -8,879 | -3,194 |
Supplemental disclosures of cash flow information | ||||||||||
Cash paid for interest | ||||||||||
3,542 | 5,534 | 5,534 | 5,534 | 5,538 | 2,750 | 7 | 579 | 1,715 | 1,771 | 1,940 |
Cash paid for income taxes, net of refunds | ||||||||||
205 | 321 | 245 | 355 | 189 | 187 | 242 | 181 | 42 | - | - |
Unpaid debt and equity issuance costs | ||||||||||
534 | 375 | 0 | - | - | - | - | - | - | - | - |
Asset retirement obligations | ||||||||||
312 | 314 | 203 | - | - | - | - | - | - | - | - |
Non-cash investing and financing activities | ||||||||||
Issuance of common stock and options related to acquisition | ||||||||||
- | - | - | - | - | 78,196 | 0 | 0 | - | - | - |
Conversion of convertible preferred stock to common stock upon initial public offering | ||||||||||
- | - | - | - | - | - | - | - | 184,550 | 0 | - |
Conversion of convertible preferred stock warrants to common stock warrants | ||||||||||
- | - | - | - | - | - | - | - | 1,535 | 0 | 0 |
Issuance of convertible preferred stock warrants in connection with note and warrant agreement and long-term debt | ||||||||||
- | - | - | - | - | - | - | - | 1,157 | 63 | 338 |
Issuance of common stock in connection with net exercise of convertible preferred stock warrants | ||||||||||
- | - | - | - | - | - | - | - | 1,392 | 0 | 0 |
Extinguishment of convertible preferred stock warrants upon initial public offering | ||||||||||
- | - | - | - | - | - | - | - | 765 | 0 | 0 |
Extinguishment of convertible preferred stock warrants as part of preferred stock warrant exchange and exercise | ||||||||||
- | - | - | - | - | - | - | - | - | 72 | 0 |
Conversion of convertible promissory notes and accrued interest into convertible preferred stock | ||||||||||
- | - | - | - | - | - | - | - | - | - | 10,876 |
Preferred stock investment received in exchange for technology license | ||||||||||
- | - | - | - | - | - | - | - | - | - | 1,340 |