| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 | Dec'13 | Sep'13 | Jun'13 | Mar'13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Revenues | ||||||||||||||||||||||||||||
Product revenue, net | ||||||||||||||||||||||||||||
20,127 | 23,654 | 21,786 | 16,953 | 10,564 | 9,543 | 6,990 | 3,797 | 2,194 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Revenue | ||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Operating expenses | ||||||||||||||||||||||||||||
Cost of sales | ||||||||||||||||||||||||||||
2,276 | 3,928 | 2,872 | 1,398 | 1,762 | 2,073 | 1,619 | 946 | 2,698 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Research and development | ||||||||||||||||||||||||||||
21,134 | 17,072 | 20,938 | 16,125 | 15,424 | 14,856 | 13,578 | 13,094 | 11,551 | 15,860 | 12,846 | 11,769 | 10,756 | 11,381 | 9,047 | 8,905 | 11,981 | 8,967 | 7,829 | 9,640 | 6,255 | 5,499 | 4,658 | 3,614 | 4,150 | 2,236 | 2,569 | 3,067 | 3,186 |
Selling, general and administrative | ||||||||||||||||||||||||||||
29,299 | 32,248 | 32,136 | 33,103 | 32,222 | 30,572 | 32,804 | 31,036 | 26,899 | 32,267 | 18,375 | 15,133 | 13,026 | 10,171 | 8,388 | 5,215 | 4,692 | 4,511 | 3,197 | 2,904 | 2,760 | 2,241 | 2,304 | 2,234 | 2,283 | 1,341 | 2,420 | 1,422 | 1,520 |
Total operating expenses | ||||||||||||||||||||||||||||
52,709 | 53,248 | 55,946 | 50,626 | 49,408 | 47,501 | 48,001 | 45,076 | 41,148 | 48,131 | 31,221 | 26,902 | 23,782 | 21,552 | 17,435 | 14,120 | 16,673 | 13,478 | 11,026 | 12,544 | 9,015 | 7,741 | 6,962 | 5,848 | 6,434 | 3,577 | 4,990 | 4,490 | 4,707 |
Loss from operations | ||||||||||||||||||||||||||||
-32,582 | -29,594 | -34,160 | -33,673 | -38,844 | -37,958 | -41,011 | -41,279 | -38,954 | -47,776 | -31,221 | -26,902 | -23,782 | -21,552 | -17,435 | -14,120 | -16,673 | -13,478 | -11,026 | -12,544 | -9,015 | -7,741 | -6,962 | -5,848 | -6,434 | -3,577 | -4,990 | -4,490 | -4,707 |
Other (expense) income | ||||||||||||||||||||||||||||
Interest income | ||||||||||||||||||||||||||||
427 | 649 | 721 | 831 | 1,011 | 995 | 1,157 | 1,254 | 1,161 | 1,269 | 1,095 | 797 | 557 | 469 | 421 | 295 | 336 | 364 | 274 | 440 | 168 | 160 | 153 | 134 | 30 | 15 | 38 | 61 | 118 |
Interest expense | ||||||||||||||||||||||||||||
4,721 | 4,529 | 4,652 | 3,949 | 3,936 | 3,937 | 3,930 | 3,926 | 3,919 | 3,906 | 3,843 | 2,887 | 632 | 709 | 561 | 202 | 276 | 165 | 202 | 0 | 204 | 86 | 96 | 106 | 111 | 113 | 113 | 112 | 108 |
Other expense | ||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | 207 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Other income | ||||||||||||||||||||||||||||
74 | -42 | -141 | 304 | 231 | 325 | 144 | 76 | 143 | -121 | -219 | 112 | -22 | - | - | -158 | -202 | - | -182 | -332 | -123 | -137 | -129 | -110 | -26 | -14 | -35 | -56 | -100 |
Total other (expense) income | ||||||||||||||||||||||||||||
-4,220 | -3,922 | -4,072 | -2,814 | -2,694 | -2,617 | -2,629 | -2,596 | -2,615 | -2,758 | -2,967 | -1,978 | -97 | -1,560 | -347 | -65 | -142 | -91 | -110 | 108 | -159 | -63 | -73 | -81 | -107 | -113 | -110 | -107 | -90 |
Net loss | ||||||||||||||||||||||||||||
-36,802 | -33,516 | -38,232 | -36,487 | -41,538 | -40,575 | -43,640 | -43,875 | -41,569 | -50,534 | -34,188 | -28,880 | -23,879 | -23,112 | -17,782 | -14,185 | -16,815 | -13,569 | -11,136 | -12,436 | -9,174 | -7,805 | -7,035 | -5,930 | -6,542 | -3,690 | -5,100 | -4,597 | -4,798 |
Net loss attributable to common stockholders | ||||||||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -5,100 | -4,597 | -4,798 |
Net loss per common share, basic and diluted | ||||||||||||||||||||||||||||
-0.95 | -0.88 | -1.00 | -0.96 | -1.09 | -1.08 | -1.15 | -1.16 | -1.10 | -1.43 | -1.07 | -0.91 | -0.75 | -0.78 | -0.65 | -0.63 | -0.78 | -0.62 | -0.52 | -0.58 | -0.43 | -0.28 | -0.45 | -0.38 | -0.86 | -4.65 | -6.46 | -5.83 | -6.08 |
Weighted average common shares outstanding, basic and diluted | ||||||||||||||||||||||||||||
38,553 | 38,217 | 38,125 | 38,010 | 37,992 | 37,869 | 37,818 | 37,697 | 37,620 | 36,647 | 31,931 | 31,826 | 31,704 | 29,428 | 27,524 | 22,666 | 21,570 | 21,555 | 21,507 | 21,475 | 21,451 | 16,698 | 15,624 | 15,619 | 7,632 | 792 | 789 | 789 | 789 |
Other comprehensive (loss) income: | ||||||||||||||||||||||||||||
Unrealized (losses) gains from available-for-sale securities, net of tax of $0 | ||||||||||||||||||||||||||||
-56 | -69 | -99 | 125 | 182 | 80 | 153 | 266 | -169 | -346 | 18 | -17 | 9 | 95 | 38 | -18 | -89 | -100 | 9 | -22 | 21 | -5 | -2 | 2 | 0 | -1 | 0 | -2 | 1 |
Total other comprehensive (loss) income | ||||||||||||||||||||||||||||
-56 | -69 | -99 | 125 | 182 | 80 | 153 | 266 | -169 | -346 | 18 | -17 | 9 | 95 | 38 | -18 | -89 | -100 | 9 | -22 | 21 | -5 | -2 | 2 | 0 | -1 | 0 | -2 | 1 |
Comprehensive loss | ||||||||||||||||||||||||||||
-36,858 | -33,585 | -38,331 | -36,362 | -41,356 | -40,495 | -43,487 | -43,609 | -41,738 | -50,880 | -34,170 | -28,897 | -23,870 | -23,017 | -17,744 | -14,203 | -16,904 | -13,669 | -11,127 | -12,458 | -9,153 | -7,811 | -7,038 | -5,928 | -6,541 | -3,691 | -5,100 | -4,600 | -4,796 |