| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 |
|---|---|---|---|---|---|---|---|---|---|
Operating expenses: | |||||||||
Research and development | |||||||||
7,467 | 6,471 | 11,721 | 15,325 | 13,114 | 8,425 | 5,688 | 4,527 | 3,552 | 1,066 |
General and administrative | |||||||||
5,971 | 7,131 | 4,526 | 6,156 | 6,965 | 7,005 | 6,416 | 5,372 | 6,857 | 3,817 |
Total operating expenses | |||||||||
13,438 | 13,602 | 16,247 | 21,481 | 20,079 | 15,430 | 12,104 | 9,899 | 10,409 | 4,883 |
Total operating loss | |||||||||
-13,438 | -13,602 | -16,247 | -21,481 | -20,079 | -15,430 | -12,104 | -9,899 | -10,409 | -4,883 |
Other income (expense): | |||||||||
Interest income | |||||||||
231 | 38 | 24 | 45 | 52 | 42 | 16 | 24 | 18 | 6 |
Interest expense | |||||||||
87 | 336 | 12 | - | - | - | - | - | - | - |
Loss from equity method investment in Galectin Sciences, LLC | |||||||||
- | - | - | - | - | -400 | - | - | - | - |
Change in fair value of warrant liabilities | |||||||||
- | - | - | - | - | - | - | - | -524 | -1,241 |
Other income | |||||||||
- | - | - | - | - | - | - | 200 | - | 489 |
Total other income (expense) | |||||||||
144 | -298 | 12 | 45 | 52 | -358 | 16 | 224 | -506 | -746 |
Net loss | |||||||||
-13,294 | -13,900 | -16,235 | -21,436 | -20,027 | -15,788 | -12,088 | -9,675 | -10,915 | -5,629 |
Preferred stock dividends | |||||||||
263 | 1,147 | 1,232 | 741 | 868 | 943 | 867 | 976 | 1,568 | 902 |
Warrant modification (Note 9) | |||||||||
6,622 | - | - | - | - | - | - | - | - | - |
Preferred stock accretion | |||||||||
- | - | - | 173 | 229 | 229 | 229 | 230 | 230 | 2,178 |
Warrant modification | |||||||||
- | - | - | - | - | - | 8,763 | - | - | - |
Net loss applicable to common stockholders | |||||||||
-20,179 | -15,047 | -17,467 | -22,350 | -21,124 | -16,960 | -21,947 | -10,881 | -12,713 | -8,709 |
Net loss per common share — basic and diluted | |||||||||
-0.39 | -0.38 | -0.49 | -0.76 | -0.88 | -0.78 | -1.30 | -0.72 | -1.06 | -0.93 |
Weighted average common shares outstanding — basic and diluted | |||||||||
52,238 | 39,414 | 35,521 | 29,216 | 24,120 | 21,849 | 16,874 | 15,131 | 11,986 | - |
Weighted average common shares outstanding - basic and diluted | |||||||||
- | - | - | - | - | - | - | - | - | 9,384 |