| Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 | Dec'14 | Sep'14 | Jun'14 | Mar'14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating Activities | |||||||||||||||||||||||
Net loss | |||||||||||||||||||||||
-28,660 | -28,947 | -27,208 | -31,610 | -27,976 | -25,260 | -22,533 | -21,198 | -24,630 | -22,533 | -28,229 | -39,557 | -37,228 | -42,901 | -39,571 | -32,456 | -36,194 | -39,311 | -33,730 | -36,516 | -41,145 | 0 | 0 | 0 |
Adjustments to reconcile net loss to net cash used in operating activities: | |||||||||||||||||||||||
(Gain) loss from the change in fair value of derivative warrant liability | |||||||||||||||||||||||
14 | 60 | 67 | -3,452 | -2,976 | -3,039 | -3,458 | 2,352 | 5,101 | 11,059 | 12,627 | -239 | 1,783 | 0 | 0 | 0 | - | - | - | - | - | - | - | - |
(Gain) from the change in fair value of derivative warrant liability | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -2,603 | -3,149 | 5,419 | 6,530 | 0 | 0 | 0 |
(Gain) from the change in fair value of the embedded derivative to the 2020 Notes | |||||||||||||||||||||||
394 | 691 | 684 | 25 | 2,637 | 3,569 | 5,760 | 4,609 | 1,751 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | 3,470 | 0 | 0 | 0 |
Loss from the change in fair value of 2017 Notes | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | -339 | -914 | -2,768 | -3,707 | -4,204 | -3,316 | -1,305 | -706 | 3,895 | 0 | 0 | 0 | - | - | - | - |
Loss on exchange or conversion of debt | |||||||||||||||||||||||
- | - | - | - | -2,202 | -2,202 | -2,202 | -3,990 | -4,933 | 0 | 0 | 0 | - | - | - | - | 232 | 0 | 0 | 0 | - | - | - | - |
Loss on extinguishment of warrant liability | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Stock-based compensation | |||||||||||||||||||||||
1,349 | 1,301 | 816 | 819 | 683 | 418 | 433 | 391 | 421 | 397 | 569 | 656 | 886 | 1,506 | 2,491 | 2,603 | 2,647 | 2,451 | 2,055 | 2,397 | 2,860 | 0 | 0 | 0 |
Depreciation and amortization | |||||||||||||||||||||||
6,656 | 6,466 | 6,456 | 6,486 | 6,520 | 6,550 | 6,585 | 6,611 | 6,641 | 6,703 | 6,806 | 6,802 | 6,747 | 6,714 | 6,574 | 6,532 | 6,573 | 6,563 | 6,557 | 5,716 | 4,880 | 0 | 0 | 0 |
Non-cash interest expense | |||||||||||||||||||||||
1,346 | 1,488 | 1,654 | 1,714 | 1,706 | 1,690 | 1,650 | 1,284 | 962 | 1,217 | 2,043 | 3,000 | 3,977 | 4,371 | 4,135 | 3,984 | 3,772 | 4,226 | 4,262 | 7,928 | 7,860 | 0 | 0 | 0 |
Other non-cash expenses | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - |
Changes in operating assets and liabilities: | |||||||||||||||||||||||
Accounts receivable | |||||||||||||||||||||||
609 | -259 | -1,277 | -163 | -528 | -606 | 79 | 84 | -68 | 164 | -310 | 336 | -269 | -55 | -645 | -1,279 | -970 | -909 | -766 | 483 | 1,003 | 0 | 0 | 0 |
Inventories | |||||||||||||||||||||||
35 | -339 | -517 | -1,168 | -1,196 | -1,030 | -450 | 177 | 904 | 1,128 | 1,411 | 1,191 | -29 | 500 | -18 | -1,512 | -805 | -1,324 | -1,339 | 776 | 711 | 0 | 0 | 0 |
Prepaid expenses and other current assets, deposits and other assets | |||||||||||||||||||||||
1,824 | 358 | 827 | 551 | 630 | 180 | 165 | -226 | -137 | -16 | 80 | -148 | 119 | 226 | 312 | 455 | -1 | -243 | -363 | -574 | -431 | 0 | 0 | 0 |
Deposits and other assets | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 |
Accounts payable, accrued expenses and long-term liabilities | |||||||||||||||||||||||
1,294 | -274 | 366 | -1,012 | -425 | -872 | -1,295 | -1,045 | -1,742 | 632 | -36 | -657 | -697 | -2,847 | -2,604 | -2,991 | -2,771 | -724 | -1,525 | -2,132 | -1,580 | 0 | 0 | 0 |
Net cash used in operating activities | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | -23,353 | -24,640 | -24,175 | -28,160 | -27,396 | -28,655 | -35,493 | -38,990 | 0 | 0 | 0 |
Net cash used in operating activities | |||||||||||||||||||||||
-20,839 | -20,495 | -17,699 | -17,209 | -15,851 | -14,340 | -15,048 | -16,930 | -20,627 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Investing Activities | |||||||||||||||||||||||
Acquisitions of property, plant and equipment | |||||||||||||||||||||||
5,989 | 7,079 | 6,692 | 4,370 | 2,233 | 1,157 | 688 | 1,300 | 1,906 | 2,100 | 2,406 | 4,364 | 5,938 | 6,713 | 6,136 | 3,585 | 1,464 | 612 | 1,232 | 2,151 | 4,894 | 0 | 0 | 0 |
Net cash used in investing activities | |||||||||||||||||||||||
-7,457 | -8,560 | -6,692 | -4,370 | -2,233 | -1,157 | -688 | -1,300 | -1,906 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Financing Activities | |||||||||||||||||||||||
Net cash used in investing activities | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | -6,713 | -6,136 | -3,441 | -1,320 | -468 | -1,088 | -4,762 | -7,505 | 0 | 0 | 0 |
Payments on secured debt | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | 9,791 | 9,791 | 10,036 | 10,036 | 504 | 586 | 271 | 351 | 318 | 340 | 333 | 9,625 | 9,824 | 0 | 0 | 0 |
Debt and equity offering costs | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | 1,095 | 920 | 2,078 | 2,760 | 3,144 | 4,029 | 2,731 | 2,943 | 3,519 | 3,607 | 5,306 | 6,938 | 5,873 | 0 | 0 | 0 |
Proceeds from issuance of common stock upon exercise of stock options and employee stock purchase plan | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 19 | 0 | 0 | 0 |
Proceeds from issuance of common stock and common stock warrants | |||||||||||||||||||||||
11,589 | 12,089 | 26,626 | 49,145 | 39,394 | 36,952 | 22,415 | -107 | 11,044 | 0 | 0 | 0 | - | - | - | - | 33,820 | 0 | 0 | 0 | - | - | - | - |
Proceeds from the exercise of warrants | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | 3,429 | 3,609 | 1,448 | 12,235 | 12,298 | 10,910 | 10,871 | 8,056 | 10,166 | 0 | 0 | 0 | - | - | - | - |
Net cash provided by financing activities | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 44,926 | 30,865 | 31,935 | 40,152 | 30,057 | 46,363 | 36,186 | 28,229 | 0 | 0 | 0 |
Net cash provided by financing activities | |||||||||||||||||||||||
10,864 | 11,683 | 26,516 | 50,016 | 40,265 | 39,049 | 26,463 | 2,255 | 3,587 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Net (decrease) increase in cash and cash equivalents | |||||||||||||||||||||||
-17,432 | -17,372 | 2,125 | 28,437 | 22,181 | 23,552 | 10,727 | -15,975 | -18,946 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Cash paid for interest | |||||||||||||||||||||||
- | - | - | - | 1,945 | 0 | 0 | 0 | - | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Cash paid for interest | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 3,694 | 4,295 | 4,510 | 4,995 | 4,642 | 3,965 | 4,497 | 5,165 | 4,213 | 0 | 0 | 0 |
Non-cash purchase of property, plant and equipment | |||||||||||||||||||||||
368 | 520 | 1,409 | 2,234 | 919 | 317 | -146 | -433 | 27 | 0 | 0 | 0 | - | - | - | 0 | - | - | - | - | 108 | 0 | 0 | 0 |
Net increase (decrease) in cash and cash equivalents | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | 14,860 | 89 | 4,319 | 10,672 | 2,193 | 16,620 | -4,069 | -18,266 | 0 | 0 | 0 |
Conversion and exchanges of convertible debt for common stock | |||||||||||||||||||||||
- | - | - | - | 3,701 | 3,700 | 3,700 | 990 | 8,652 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Accrued debt and equity issuance costs | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |
Accrued offering costs | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - | - | - | - | 0 |
Conversion of convertible debt to common stock | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | - | - | - | - |
Fair value of warrants at issuance and upon exercise, net | |||||||||||||||||||||||
- | - | - | - | - | - | - | - | -4,353 | 0 | 0 | 0 | - | - | - | - | - | - | - | - | - | - | - | - |