| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 |
|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||
Net loss | ||||||||
-54,074 | -54,698 | -48,500 | -44,498 | -32,611 | -38,794 | -49,402 | -32,736 | -26,037 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||
Depreciation and amortization | ||||||||
329 | 292 | 251 | 205 | 169 | 134 | 125 | 32 | 6 |
Stock-based compensation expense | ||||||||
8,244 | 6,862 | 5,728 | 5,140 | 3,089 | 10,799 | 18,169 | 1,374 | 605 |
In process research and development expenses | ||||||||
2,805 | 1,600 | 0 | 1,000 | 1,000 | 0 | 8,261 | 20,500 | 20,898 |
Amortization of operating lease right-of-use assets | ||||||||
566 | - | - | - | 565 | - | - | - | - |
Amortization of long-term debt discount and issuance costs | ||||||||
89 | - | - | - | - | - | - | - | - |
Amortization of premium on investments, net of accretion of discounts | ||||||||
65 | - | - | - | - | - | - | - | - |
Net realized gain on investments | ||||||||
39 | - | - | - | - | - | - | - | - |
Changes in operating assets and liabilities: | ||||||||
Prepaid expenses and other current assets | ||||||||
1,785 | 1,586 | -1,436 | 771 | 3,472 | 1,385 | 1,151 | 197 | 94 |
Other assets | ||||||||
-925 | 172 | 20 | -762 | -2,144 | -239 | 398 | 0 | 425 |
Operating lease liabilities | ||||||||
566 | - | - | - | 504 | - | - | - | - |
Accounts payable | ||||||||
1,609 | -1,732 | -490 | -1,309 | 2,132 | -1,440 | 2,742 | 237 | 546 |
Accrued expenses | ||||||||
-2,239 | 2,281 | 258 | -229 | -789 | 2,675 | 933 | 1,889 | 441 |
Accrued research and development expenses | ||||||||
-2,461 | 87 | 3,894 | 2,552 | 2,072 | 2,749 | 5,206 | 2,698 | -126 |
Accrued compensation and benefits | ||||||||
-5,633 | 2,917 | 2,075 | 1,757 | -1,569 | - | - | - | 593 |
Accrued interest expense | ||||||||
- | - | - | - | - | 0 | 0 | -2 | -115 |
Net cash used in operating activities | ||||||||
-52,295 | -44,140 | -36,110 | -36,810 | -27,774 | -25,023 | -15,515 | -6,798 | -3,708 |
Cash flows from investing activities | ||||||||
Research and development asset acquisitions, net of cash acquired | ||||||||
2,805 | 1,600 | 0 | 1,000 | 1,000 | 0 | 8,261 | 20,636 | -11,176 |
Purchase of marketable securities | ||||||||
73,778 | - | - | - | 222,295 | - | - | - | - |
Maturities of marketable securities | ||||||||
89,083 | - | - | - | 20,000 | - | - | - | - |
Sales of marketable securities | ||||||||
16,051 | - | - | - | 5,500 | - | - | - | - |
Purchase of property and equipment | ||||||||
513 | 528 | 711 | 1,380 | 347 | 322 | 1,716 | 941 | 511 |
Net cash provided by (used in) investing activities | ||||||||
28,038 | 46,933 | 17,949 | -13,884 | -198,142 | -8,681 | -105,116 | -41,579 | 10,665 |
Cash flows from financing activities | ||||||||
Proceeds from issuance of common stock | ||||||||
- | 0 | 0 | 38 | 291,273 | - | - | - | - |
Proceeds from the exercise of stock options | ||||||||
15 | 1,518 | 369 | 87 | 71 | - | - | - | - |
Proceeds from issuance of convertible preferred stock, net | ||||||||
- | - | - | - | - | - | - | 1,547 | 71,944 |
Repayment of notes payable to related parties | ||||||||
- | - | - | - | - | 0 | 0 | 0 | 40 |
Net cash provided by financing activities | ||||||||
571 | 1,518 | 369 | 28,347 | 291,344 | -2,144 | 229,552 | 1,547 | 71,904 |
Effect of exchange rate changes on cash and cash equivalents | ||||||||
-50 | - | - | - | - | - | - | - | - |
Net increase (decrease) in cash and cash equivalents | ||||||||
-23,686 | 4,311 | -17,792 | -22,347 | 65,428 | -35,848 | 108,921 | -46,830 | 78,861 |
Cash paid for interest | ||||||||
618 | - | - | - | - | - | - | - | - |
Supplemental disclosure of noncash investing and financing activities: | ||||||||
Acquisition of in-process research and development through issuance of stock | ||||||||
- | - | - | - | - | 0 | 0 | 0 | 19,284 |
Issuance of Series A convertible preferred stock to convert debt and accrued interest | ||||||||
- | - | - | - | - | 0 | 0 | 0 | 6,124 |
Right-of-use assets obtained in exchange for lease liabilities | ||||||||
- | - | - | - | 12,458 | - | - | - | - |
Change in unrealized gain (loss) on marketable securities, net of tax | ||||||||
-676 | -179 | -55 | 425 | 140 | - | - | - | - |
Unpaid property and equipment | ||||||||
60 | 56 | -141 | -471 | 739 | - | - | - | 43 |
Conversion of convertible preferred stock to common stock | ||||||||
- | 0 | 0 | 0 | 338,367 | - | - | - | - |
Employee Stock Purchase Plan | ||||||||
Proceeds from issuance of common stock | ||||||||
556 | - | - | - | - | - | - | - | - |